amiphenazole

used as a respiratory tonic, morphine antagonist, & antidote in barbiturate poisoning; RN given refers to parent cpd; sturcture

Also Known As:

Daptazile; amiphenazole monohydrobromide; amiphenazole monohydrochloride; 2,4-diamino-5-phenylthiazole

Networked: 22 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Sulfur Compounds: 278
  - Thiazoles: 392
    - amiphenazole: 22
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Thiazoles: 392
      - amiphenazole: 22

Related Diseases

1.	Respiratory Insufficiency (Respiratory Failure) 10/01/1963 - "ORAL AMIPHENAZOLE IN CHRONIC RESPIRATORY FAILURE." 01/27/1962 - "Use of amiphenazole in respiratory failure." 01/01/1976 - "It could be proved that with 2,4-diamino-5-phenylthiazol (aminophenazol; Daptazile) respiratory depression associated associated with chronic obstructive pulmonary diseases can be influenced and that here is statistically significant improvement of respiration. " 05/25/1961 - "[The effect of amiphenazole (Daptazole) on the respiratory depression caused by pethidine]." 03/20/1965 - "ORAL RESPIRATORY STIMULANTS IN CHRONIC RESPIRATORY FAILURE: DOUBLE-BLIND CONTROLLED TRIAL OF AMIPHENAZOLE AND DICHLORPHENAMIDE."
2.	Chronic Obstructive Pulmonary Disease (COPD) 01/01/1976 - "It could be proved that with 2,4-diamino-5-phenylthiazol (aminophenazol; Daptazile) respiratory depression associated associated with chronic obstructive pulmonary diseases can be influenced and that here is statistically significant improvement of respiration. "
3.	Poisoning 03/13/1965 - "[CLINICAL REPORT ON THE EFFECTIVENESS OF DAPTAZOLE (AMIPHENAZOLE) IN A CASE OF VALIUM POISONING]." 11/10/1956 - "Arousing effect of megimide and amiphenazole in allypropymal poisoning." 03/29/1958 - "Massive doses of bemegride and amiphenazole in treatment of barbiturate poisoning." 08/24/1957 - "Treatment of acute primidone poisoning with bemegride and amiphenazole." 05/25/1957 - "Bemegride amiphenazole and barbiturate poisoning; the present position."
4.	Intractable Pain 01/01/1958 - "The treatment of intractable pain with large doses of morphine and amiphenazole (daptazole)." 01/21/1956 - "Further experience with amiphenazole and morphine in intractable pain."
5.	Substance-Related Disorders (Drug Abuse) 02/02/1957 - "Amiphenazole in a case of drug addiction."

Related Drugs and Biologics

1.	Respiratory System Agents (Respiratory Stimulants)
2.	Dichlorphenamide (Daranide)
3.	Bemegride
4.	barbituric acid (barbiturate)
5.	Morphine (MS Contin)
6.	Opiate Alkaloids
7.	Primidone (Sertan)
8.	Naloxone (Narcan)
9.	Meperidine (Pethidine)
10.	Levallorphan (Lorfan)

Related Therapies and Procedures

1.	Analgesia