acetoxycycloheximide

02/01/1972 - "It has previously been shown that rats trained 5 hr after intracerebral injection of acetoxycycloheximide show a transient amnesia at 24 hr after training. "
06/01/1971 - "Acetoxycycloheximide and transient amnesia in the rat."
02/01/1972 - "Acetoxycycloheximide-induced transient amnesia: protective effects of adrenergic stimulants."
02/01/1973 - "Mice and rats trained after treatment with cycloheximide or acetoxycycloheximide in a conditioned avoidance response develop an amnesia of their training experience. "
07/01/1977 - "We conclude that inhibition of cerebral protein synthesis can best account for amnesia induced by anisomycin, cycloheximide, and acetoxycycloheximide."

02/15/2005 - "In this study we show that a close structural derivative of CHX, acetoxycycloheximide (E-73) induced rapid processing of procaspases and subsequent apoptosis with much higher efficacy than CHX in human leukemia Jurkat T cells. "
02/27/2009 - "The protein synthesis inhibitor acetoxycycloheximide (Ac-CHX) has been previously shown to induce rapid apoptosis mediated by the release of cytochrome c in human leukemia Jurkat cells. "
02/27/2009 - "Caspase-8 mediates mitochondrial release of pro-apoptotic proteins in a manner independent of its proteolytic activity in apoptosis induced by the protein synthesis inhibitor acetoxycycloheximide in human leukemia Jurkat cells."

04/01/2008 - "Nevertheless, we have surprisingly found that CHX, as well as its structural analogue acetoxycycloheximide (Ac-CHX), prevents TNF-alpha-mediated activation of NF-kappaB and caspase-8 in human lung carcinoma A549 cells. "
06/01/2008 - "The protein synthesis inhibitor cycloheximide (CHX) and its structural derivative acetoxycycloheximide (Ac-CHX) have been recently shown to block the TNF-alpha-induced activation of NF-kappaB via ectodomain shedding of TNF receptor 1 (TNF-R1) in human lung carcinoma A549 cells. "

07/16/1971 - "Mature animals that have "outgrown" their genetic susceptibility to audiogenic seizures are made susceptible again by acetoxycycloheximide. "

07/16/1971 - "Acetoxycycloheximide enhances audiogenic seizures in DBA-2J mice."
07/16/1971 - "Mature animals that have "outgrown" their genetic susceptibility to audiogenic seizures are made susceptible again by acetoxycycloheximide. "