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1,1,3,3-tetramethylurea

structure

Also Known As:

tetramethylurea

Networked: 7 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amides: 2428
  - Urea: 15015
    - Methylurea Compounds
      - 1,1,3,3-tetramethylurea: 7

Experts

1.	Chen, Jianxin: 1 article (06/2018)
2.	Ding, Bei: 1 article (06/2018)
3.	Gai, Feng: 1 article (06/2018)
4.	Gao, Yiqin: 1 article (06/2018)
5.	Mukherjee, Debopreeti: 1 article (06/2018)
6.	Yang, Lijiang: 1 article (06/2018)

Related Diseases

1.	Experimental Melanoma 04/01/1991 - "The present study indicates that DMTU as well as another growth inhibitory methylurea derivative, tetramethylurea (TMU) significantly decrease ATP content in the B16 melanoma cell line. "
2.	Hyperlipoproteinemias 07/01/1973 - "In this study, we have used polyacrylamide gel electrophoresis of apoprotein components that are soluble in tetramethylurea to show that the very low-density lipoprotein fraction of blood serum from seven patients with hyperlipoproteinemia contains unusually large amounts of an arginine-rich protein. "
3.	Acute Erythroblastic Leukemia (Erythroleukemia) 09/01/1981 - "A series of derivatives of tetramethylurea, a known inducer of the differentiation of Friend erythroleukemia cells, has been synthesized and tested for its capacity to induce erythroid maturation, as measured by the synthesis of hemoglobin. " 11/20/1981 - "Other inducers of differentiation (i.e., dimethylformamide, bis(acetyl)diaminopentane) also inhibited the rate of wheat germ agglutinin-induced agglutination of erythroleukemia cells while, in contrast, the inducer tetramethylurea did not. "
4.	Hypertriglyceridemia 11/01/1985 - "VLDL, intermediate (IDL) and low-density lipoprotein (LDL) apoprotein (apo)-B radioactivity (tetramethylurea insoluble) following injection of 125I-labeled alpha 2- and beta-VLDL decayed biphasically in all subjects, and this decay in normolipidemic subjects was more rapid than in subjects with broad beta disease (P = 0.004) or endogenous hypertriglyceridemia (P = 0.004 for alpha 2- and P = 0.010 for beta-VLDL). "
5.	Neoplasms (Cancer) 01/01/1980 - "Effects of the differentiating agents (inducers) dimethylacetamide, di- and tetramethylurea on epidermal tumor promotion by retinyl (vitamin A) acetate and croton oil in hamster cheek pouch." 01/01/1980 - "The cell-differentiating agents (inducers) dimethylacetamide, dimethylurea and tetramethylurea significantly lowered the yields and/or incidences of total tumors, benign plaques, benign hyperkeratotic lesions and advanced tumors promoted by retinyl acetate or croton oil after initiation by 7,12-dimethylbenz(a)anthracene. "

Related Drugs and Biologics

1.	Apoproteins
2.	Proteins (Proteins, Gene)
3.	VLDL Lipoproteins
4.	Arginine (L-Arginine)
5.	Adenosine Triphosphate (ATP)
6.	1,3-dimethylthiourea
7.	polyacrylamide
8.	methylurea
9.	IDL Lipoproteins (Lipoprotein, IDL)
10.	9,10-Dimethyl-1,2-benzanthracene