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trimethyl phosphate

request from searcher; structure

Also Known As:

trimethylphosphate; phosphoric acid trimethyl ester

Networked: 8 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Organophosphorus Compounds: 300
  - Organophosphates: 1942
    - trimethyl phosphate: 8

Related Diseases

1.	Infertility (Sterility) 03/01/1976 - "A proposed mechanism for trimethylphosphate-induced sterility." 06/01/1994 - "Both dimethyl methylphosphonate (DMMP) and trimethylphosphate (TMP) are organophosphorous compounds that can evoke sterility in male rodents. "
2.	Chromosome Aberrations (Chromosome Abnormalities) 01/01/1975 - "5. Tests with 2 times 500 or 5 times 1000 mg/kg trimethylphosphate orally showed an increase in chromosome aberrations compared with controls indicating mutagenic effects in both cases; with 5 times 1000 mg/kg p.o., however, the figures were low as a result of marked mitotic inhibition. " 09/01/1986 - "Conversely, it appeared that with MMS-type mutagens (MMS; dimethyl sulfate, DMS; trimethyl phosphate, TMP), alkylation products such as 7-methylguanine and 3-methyladenine, if unrepaired or misrepaired, are potentially mutagenic lesions causing both mutations and chromosomal aberrations."
3.	Body Weight (Weight, Body) 01/01/1978 - "Groups of 50 rats and 50 mice of each sex were administered trimethylphosphate in distilled water three times per week at one of two doses, either 50 or 100 mg/kg body weight for the rats and either 250 or 500 mg/kg body weight for the mice. " 11/01/1997 - "Trimethylphosphate (TMPO) was administered to 50 male and 50 female Wistar rats through their drinking water at doses of 0, 1, 10, or 100 mg/kg body weight up to 30 months. "
4.	Aspermia 10/01/1980 - "Trimethylphosphate (TMP) causes aspermia in D. "
5.	Fibroma (Fibromatosis) 01/01/1978 - "Trimethylphosphate was associated with the induction of benign fibromas of the subcutaneous tissue in male Fischer 344 rats. "

Related Drugs and Biologics

1.	Thymidine Monophosphate (TMP)
2.	Drinking Water
3.	Mutagens
4.	Chemosterilants
5.	alpha-Chlorohydrin
6.	3,3,5,5-tetramethyl-1-pyrroline N-oxide (TMPO)
7.	dimethyl methylphosphonate
8.	3-methyladenine
9.	7-methylguanine
10.	dimethyl sulfate