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16-dehydropregnenolone

Also Known As:

3 beta-hydroxypregna-5,16-dien-20-one

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Fused-Ring Compounds
  - Steroids: 70059
    - Pregnanes: 9
      - Pregnenes: 1
        Pregnenolone: 356
        16-dehydropregnenolone: 3
Hormones, Hormone Substitutes, and Hormone Antagonists
- Hormones: 80400
  - Adrenal Cortex Hormones: 62914
    - Hydroxycorticosteroids: 7
      - Pregnenolone: 356
        16-dehydropregnenolone: 3
  - Gonadal Hormones: 716
    - Gonadal Steroid Hormones: 7657
      - Progesterone Congeners: 320
        Pregnenolone: 356
        16-dehydropregnenolone: 3

Experts

1.	Barreira, Luísa: 1 article (01/2017)
2.	Lopes, Susana M M: 1 article (01/2017)
3.	Marques, Cátia: 1 article (01/2017)
4.	Pinho E Melo, Teresa M V D: 1 article (01/2017)
5.	Rodrigues, Maria João: 1 article (01/2017)
6.	Sousa, Emanuel P: 1 article (01/2017)
7.	Bratoeff, Eugene: 1 article (12/2015)
8.	Cabeza, Marisa: 1 article (12/2015)
9.	Heuze, Yvonne: 1 article (12/2015)
10.	Ramírez-Apan, Teresa: 1 article (12/2015)

Related Diseases

1.	Neoplasms (Cancer) 12/15/2015 - "Synthesis and activity of novel 16-dehydropregnenolone acetate derivatives as inhibitors of type 1 5α-reductase and on cancer cell line SK-LU-1." 01/01/2012 - "The natural pregnane steroid 16-dehydropregnenolone (16-DHP) showed the growth inhibitory activity against human tumor cells; however, the mechanisms of actions of 16-DHP were not clarified. "
2.	Lymphoma (Lymphomas) 01/01/2017 - "Hexacyclic steroids bearing a benzyl group at C-22, derived from 16-dehydropregnenolone and 16-dehydroprogesterone, show considerable cytotoxicity against EL4 (murine T-lymphoma) in contrast with the corresponding C-22-unsubstituted derivatives showing low cytotoxicity. "

Related Drugs and Biologics

1.	Steroids
2.	Acetates (Acetic Acid Esters)
3.	16-dehydroprogesterone