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polystyrene sulfonic acid (sodium polystyrene sulfonate)

Subscribe to New Research on polystyrene sulfonic acid

RN given refers to homopolymer with locant for ethenyl moiety in position 4; Ca salt is potassium absorbing resin administered orally for treatment of hyperkalemia

Also Known As:

sodium polystyrene sulfonate; polystyrene sulfonate; Kalimate; Kayexalate; PSSO3; Resonium-A; calcium polystyrene sulfonate; calcium resonium; poly(styrenesulfonate); polystyrene sulfonic acid, homopolymer, calcium salt; polystyrene sulfonic acid, homopolymer, sodium salt

Networked: 128 relevant articles (6 outcomes, 9 trials/studies)

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Drug Context: Research Results

Experts

1.	Yuan, Christina M: 3 articles (04/2014 - 09/2012)
2.	Abbott, Kevin C: 3 articles (04/2014 - 09/2012)
3.	Nee, Robert: 2 articles (04/2014 - 09/2013)
4.	Watson, Maura A: 2 articles (04/2014 - 09/2012)
5.	Little, Dustin J: 2 articles (04/2014 - 09/2013)
6.	Anderson, Robert A: 2 articles (06/2004 - 08/2002)
7.	Zaneveld, Lourens J D: 2 articles (06/2004 - 08/2002)
8.	Waller, Donald P: 2 articles (06/2004 - 08/2002)
9.	Anderson, R A: 2 articles (12/2001 - 11/2000)
10.	Zaneveld, L J: 2 articles (12/2001 - 11/2000)

Related Diseases

1.	Hyperkalemia 01/01/2015 - "Sodium polystyrene sulfonate – is it truly effective treatment for hyperkalemia?" 12/07/2015 - "This study aimed to evaluate the efficacy of sodium polystyrene sulfonate in the treatment of mild hyperkalemia. " 12/07/2015 - "Sodium polystyrene sulfonate has long been prescribed for this condition, although evidence is lacking on its efficacy for the treatment of mild hyperkalemia over several days. " 04/01/2014 - "This analysis may guide decisions regarding adoption of alternative agents for chronic hyperkalemia control, and suggests that sodium polystyrene sulfonate be employed as an active control in clinical trials of these agents." 01/01/2016 - "The primary objective of this review is to analyze the efficacy and safety of patiromer to treat hyperkalemia and compare its pharmacokinetics to currently available sodium polystyrene sulfonate (SPS) therapy. "
2.	Keratitis 01/01/1996 - "We present here the results of experiments designed to assess the efficacy of a BAC-free and EDTA-free formulation of ciprofloxacin, Ciprofloxacin-polystyrene sulfonate (PSS), in experimental models of Pseudomonas aeruginosa and Staphylococcus aureus keratitis. " 08/01/1998 - "This study, employing an experimental rabbit model of Staphylococcus keratitis, compared the effectiveness of two commonly prescribed formulations of fluoroquinolones to an experimental formulation, ciprofloxacin with polystyrene sulfonate (ciprofloxacin-PSS). " 08/01/1998 - "Effectiveness of ciprofloxacin-polystyrene sulfonate (PSS), ciprofloxacin and ofloxacin in a Staphylococcus keratitis model."
3.	Hemorrhage 04/01/2015 - "We report two cases of patients with chronic renal failure showing rectal bleeding due to digestive ulcers, associated with Kayexalate(®) alone. " 09/01/1999 - "We conclude that to use early continuous regular insulin infusion therapy for the treatment of non-oliguric hyperkalemia in VLBW infants is more effective than kayexalate in decreasing the duration of hyperkalemia and reducing the incidence of intraventricular hemorrhage."
4.	Thrombocytopenia (Thrombopenia) 11/01/1997 - "This thrombocytopenia rapidly improved after cessation of Kayexalate administration. " 11/01/1997 - "This is the first reported case of thrombocytopenia caused by Kayexalate administration." 11/01/1997 - "The complication of thrombocytopenia associated with Kayexalate has not been reported. " 11/01/1997 - "However, after 7 days from the start of Kayexalate therapy, thrombocytopenia progressed gradually, and 12 days later the initial platelet count of 20.7 x 10(4)/microliter decreased to 8.6 x 10(4)/microliter. " 11/01/1997 - "[Thrombocytopenia associated with sodium polystyrene sulfonate]."
5.	Heart Diseases (Heart Disease) 10/01/1991 - "Supportive treatment consisted of intravenous catecholamines, sodium polystyrene sulfonate, and dialysis, and all patients recovered completely without any residual hepatic or cardiac disease. "

Related Drugs and Biologics

1.	Ciprofloxacin (Cipro)
2.	Insulin (Novolin)
3.	Edetic Acid (EDTA)
4.	Catecholamines
5.	Sorbitol (Yal)
6.	Potassium
7.	Lithium
8.	sevelamer (RenaGel)
9.	Pertussis Toxin
10.	Fluoroquinolones

Related Therapies and Procedures

1.	Enema (Enemas)
2.	Transplants (Transplant)
3.	Renal Dialysis (Hemodialysis)
4.	Rectal Administration
5.	Kidney Transplantation