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sodium pyrophosphate (disodium pyrophosphate)

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RN refers to diphosphoric acid, tetra-Na salt; structure
Also Known As:
disodium pyrophosphate; sodium diphosphate; anhydrous sodium pyrophosphate; tetrasodium pyrophosphate; tetrasodium pyrophosphate, 32P2-labeled cpd; tetrasodium pyrophosphate, decahydrate; trisodium pyrophosphate; diphosphoric acid, tetrasodium salt
Networked: 24 relevant articles (2 outcomes, 12 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1. Proskin, H M: 3 articles (01/2000 - 01/2000)
2. DeVizio, W: 3 articles (01/2000 - 01/2000)
3. Petrone, M E: 3 articles (01/2000 - 01/2000)
4. Volpe, A R: 3 articles (01/2000 - 01/2000)
5. Sowinski, J: 2 articles (01/2000 - 01/2000)
6. Battista, G: 2 articles (01/2000 - 01/2000)
7. Petrone, D M: 2 articles (01/2000 - 01/2000)
8. Abbasi, Imtiaz Ahmed: 1 article (08/2012)
9. Yan, Dickson Y S: 1 article (01/2012)
10. Lo, Irene M C: 1 article (01/2012)

Related Diseases

1. Calculi (Calculus)
01/01/1998 - "This clinical study compared the effect of a dental floss containing 0.25 mg tetrasodium pyrophosphate per cm and a placebo floss on supragingival calculus formation using a 6-week, partial-mouth toothshield model. "
01/01/1990 - "A two phase, six month, double blind clinical study was conducted to compare the effect on supragingival calculus deposits of a dentifrice containing 1.30% soluble pyrophosphate (from 2.0% tetrasodium pyrophosphate) with and without the presence of 1.50% of a copolymer of methoxyethylene and maleic acid. "
01/01/1990 - "A six-month, double blind, clinical study was conducted to determine the effect on supragingival calculus formation of a dentifrice containing 1.30% soluble pyrophosphate (from 2.0% tetrasodium pyrophosphate) and 1.50% of a copolymer of methoxyethylene and maleic acid, as compared to a dentifrice containing the same amount of soluble pyrophosphate but without the copolymer. "
01/01/2000 - "The results of this clinical study support the conclusion that a new calculus-inhibiting dentifrice, containing tetrasodium pyrophosphate, sodium tripolyphosphate, and a copolymer in a 0.243% sodium fluoride/silica base, is efficacious for the control of the development of supragingival calculus, and provides a level of benefit greater than that provided by a commercially available calculus-inhibiting dentifrice containing tetrasodium pyrophosphate and a copolymer in a 0.243% sodium fluoride/silica base."
01/01/2000 - "The objective of this double-blind clinical study, conducted using the Volpe-Manhold evaluation method for dental calculus, was to compare the effect on supragingival calculus formation of a dentifrice containing tetrasodium pyrophosphate, sodium tripolyphosphate, and a copolymer in a 0.243% sodium fluoride/silica base (Test Dentifrice), to that of a commercially available calculus-inhibiting dentifrice containing tetrasodium pyrophosphate and a copolymer in a 0.243% sodium fluoride/silica base (Positive Control Dentifrice). "
2. Dental Calculus
09/01/1989 - "A double-blind clinical study was conducted to evaluate the effect of a tartar-control dentifrice containing 1% sodium polyphosphate as tartar control agent compared with dentifrice A containing 5% sodium pyrophosphate and a placebo dentifrice. "
05/01/1997 - "Thirty-eight students were randomly assigned to either the experimental group using a tartar-control dentifrice (containing tetrapotassium pyrophosphate, PEG-6, disodium pyrophosphate, and tetrasodium pyrosulphate in a 5.0% soluble pyrophosphate formulation) or the control group using a regular dentifrice. "
01/01/2000 - "The objective of this double-blind clinical study, conducted using the Volpe-Manhold evaluation method for dental calculus, was to compare the effect on supragingival calculus formation of a dentifrice containing tetrasodium pyrophosphate, sodium tripolyphosphate, and a copolymer in a 0.243% sodium fluoride/silica base (Test Dentifrice), to that of a commercially available calculus-inhibiting dentifrice containing tetrasodium pyrophosphate and a copolymer in a 0.243% sodium fluoride/silica base (Positive Control Dentifrice). "
01/01/1998 - "The objective of this double-blind clinical study was to investigate the anticalculus efficacy of a new improved tartar control dentifrice formulation containing tetrasodium pyrophosphate, sodium tripolyphosphate, PVM/MA copolymer and 0.243% sodium fluoride in a silica base (New and Improved Colgate Tartar Control Fluoride Toothpaste with Micro-Cleaning Crystals) as the test dentifrice, compared to a previously marketed, American Dental Association-accepted, tartar control dentifrice formulation containing tetrasodium pyrophosphate, PVM/MA copolymer and 0.243% sodium fluoride in a silica base (Colgate Tartar Control Fluoride Toothpaste with Micro-Cleaning Crystals), as the positive control dentifrice. "
01/01/2000 - "The objective of this double-blind clinical study, conducted in harmony with the Volpe-Manhold design for studies of dental calculus, was to compare the effect on supragingival calculus formation of a dentifrice containing pyrophosphate, tripolyphosphate and a copolymer in a 0.243% sodium fluoride/silica base (Test Dentifrice), to that of a commercially available calculus-inhibiting dentifrice containing tetrapotassium pyrophosphate, disodium pyrophosphate and tetrasodium pyrophosphate in a 0.243% sodium fluoride/silica base (Positive Control Dentifrice). "
3. Neoplasms (Cancer)
4. Pain (Aches)
5. Flushing

Related Drugs and Biologics

1. Dentifrices (Dentifrice)
2. Sodium Fluoride (Ossin)
3. Silicon Dioxide (Sand)
4. triphosphoric acid (triphosphate)
5. methoxyethylene-maleic anhydride copolymer
6. Toothpastes
7. Fluorides
8. hydrated silica gel-based toothpaste
9. sodium pyrophosphate (disodium pyrophosphate)
10. tetrapotassium pyrophosphate

Related Therapies and Procedures

1. Tooth Bleaching
2. Home Care Dental Devices (Dental Floss)