pluramycin

Also Known As:

10-(4-O-acetyl-2,3,6-trideoxy-3-(dimethylamino)- 3-C-methyl-alpha-L-lyxo-hexopyranosyl)-11-hydroxy-5-methyl-2-(2-methyl-3-(1-propenyl)oxir anyl)-8-(2,3,6-trideoxy-3-(dimethylamino)-beta-D- arabino-hexopyranosyl)-4H-anthra(1,2-b)pyran- 4,7,12-trione

Networked: 7 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Carbohydrates: 22023
- Glycosides: 2119
  - Aminoglycosides: 5131
    - pluramycin: 7

Related Diseases

1.	Neoplasms (Cancer) 09/01/1957 - "Antitumor effect of pluramycin A on experimental animal tumors; studies on antitumor products of Streptomyces. " 04/01/1983 - "In our laboratory, we have studied the mechanism of action of tumor-inhibitory antibiotics, including bleomycin, phleomycin, adriamycin, aclarubicin, neothramycin, macromomycin, auromomycin, chartreusin, pluramycin, neopluramycin, xanthomycin A, angustmycins A and C, blasticidin S and phenomycin. "
2.	Carcinoma (Carcinomatosis) 07/01/1957 - "Effect of pluramycin A on Ehrlich carcinoma of mice; studies on antitumor substance produced by actinomycetes. " 01/01/1956 - "Antitumor effect of pluramycin crude powder on Ehrlich carcinoma of mice. "
3.	Sarcoma (Soft Tissue Sarcoma) 12/01/1956 - "[Cytostatic effect of antibiotics (actinomycin J, sarkomycin and pluramycin) on Yoshida ascites sarcoma cells]."
4.	Decompression Sickness (Bends) 08/20/1996 - "We have used various chemical probes [(+)-CC-1065, a minor-groove-specific agent that alkylates N3 of adenine and traps bends into the minor groove; pluramycin, a minor-major-groove threading intercalator that alkylates N7 of guanine; KMnO4, which reacts more strongly with bases in denatured DNA] to gain more information on the interaction of IHF with the H' site of phage lambda. "
5.	Breast Neoplasms (Breast Cancer) 10/01/2023 - "Rubiflavin G, photorubiflavin G, and photorubiflavin E: Novel pluramycin derivatives from Streptomyces sp. W2061 and their anticancer activity against breast cancer cells."

Related Drugs and Biologics

1.	Anti-Bacterial Agents (Antibiotics)
2.	Cytostatic Agents
3.	Aclarubicin
4.	Powders
5.	Phleomycins
6.	Intercalating Agents
7.	Guanine
8.	Doxorubicin (Adriamycin)
9.	DNA (Deoxyribonucleic Acid)
10.	Dactinomycin (Actinomycin)