HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

picolinamide

degradation product of diquat

Networked: 19 relevant articles (0 outcomes, 3 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyridines: 88
    - Picolinic Acids: 1
      - picolinamide: 19
- Heterocyclic Acids
  - Picolinic Acids: 1
    - picolinamide: 19

Experts

1.	Lan, Xiaoli: 2 articles (11/2017 - 01/2016)
2.	Liu, Qingyao: 2 articles (11/2017 - 01/2016)
3.	Zhang, Yongxue: 2 articles (11/2017 - 01/2016)
4.	McGowan, Patrick C: 2 articles (05/2017 - 12/2009)
5.	Gowrishankar, Shanmugaraj: 1 article (01/2022)
6.	Jothipandiyan, Sowndarya: 1 article (01/2022)
7.	Pandian, Shunmugiah Karutha: 1 article (01/2022)
8.	Paramasivam, Nithyanand: 1 article (01/2022)
9.	Sankaran, Sankaran Venkatachalam: 1 article (01/2022)
10.	Sekaran, Saravanan: 1 article (01/2022)

Related Diseases

1.	Infections 01/01/2022 - "As a whole, the present study showed that the novel thiazolinyl-picolinamide based Pd(II) complexes offer a promising anti-infective strategy to combat biofilm-mediated implant infections." 01/01/2020 - "Overall, the present study demonstrates that thiazolinyl-picolinamide based palladium (II) complexes will be a promising strategy to combat device-mediated UTI infections." 06/01/2022 - "Hence to overcome biofilm mediated implant infections, we developed a novel antibiofilm agent, palladium (II) thiazolinyl picolinamide complex (Pd(II)-E). "
2.	Neoplasms (Cancer) 12/10/2009 - "We show that the binding mode adopted by picolinamide derivatives in organometallic Os(II) and Ru(II) half-sandwich complexes can lead to contrasting cancer cell cytotoxicity. " 05/05/2017 - "Bis-picolinamide Ruthenium(III) Dihalide Complexes: Dichloride-to-Diiodide Exchange Generates Single trans Isomers with High Potency and Cancer Cell Selectivity." 01/01/2011 - "In present study, we designed and synthesized a novel vascular endothelial growth factor receptor (VEGFR) inhibitor N-methyl-4-(4-(3-(trifluoromethyl) benzamido) phenoxy) picolinamide SKLB610 that potently suppresses human tumor angiogenesis. "
3.	Melanoma (Melanoma, Malignant) 02/14/2013 - "Development of 18F-labeled picolinamide probes for PET imaging of malignant melanoma." 06/16/2021 - "Development of Radiofluorinated Nicotinamide/Picolinamide Derivatives as Diagnostic Probes for the Detection of Melanoma." 11/06/2017 - "Although 18F-5-fluoro-N-(2-[diethylamino]ethyl)picolinamide (18F-5-FPN) is considered a promising radiopharmaceutical for PET imaging of melanoma, it accumulates at high concentrations in the liver. " 01/01/2016 - "(18)F-5-Fluoro-N-(2-[diethylamino]ethyl)picolinamide ((18)F-5-FPN), a benzamide analogue, was prepared and its pharmacokinetics and binding affinity evaluated both in vitro and in vivo to assess its clinical potential in the diagnosis and staging of melanoma. "
4.	Islet Cell Adenoma (Islet Cell Tumors) 11/01/1978 - "Pancreatic islet cell tumors were induced in 32 of 49 male Wistar rats (73%) surviving 9 months or longer following treatment with streptozotocin alone, with streptozotocin and nicotinamide, or with streptozotocin and picolinamide. " 04/01/1985 - "Ten to 16 months after the injection of streptozotocin (50 mg/kg body weight i.v.) and 3-aminobenzamide (345 mg/kg i.v.), streptozotocin (50 mg/kg) and nicotinamide (350 mg/kg i.p.), streptozotocin (50 mg/kg) and picolinamide (250 mg/kg i.p.), alloxan (40 mg/kg i.v.) and nicotinamide (350 mg/kg), alloxan (40 mg/kg) and 3-aminobenzamide (345 mg/kg), and alloxan (40 mg/kg) and picolinamide (250 mg/kg), pancreatic islet cell tumors developed in 100, 98, 60, 26, 22, and 20% of surviving rats, respectively. "
5.	Body Weight (Weight, Body) 07/01/1978 - "injection of picolinamide, 250 mg/kg of body weight, 15 min before a single i.v. injection of streptozotocin, 65 mg/kg of body weight. " 04/01/1985 - "Ten to 16 months after the injection of streptozotocin (50 mg/kg body weight i.v.) and 3-aminobenzamide (345 mg/kg i.v.), streptozotocin (50 mg/kg) and nicotinamide (350 mg/kg i.p.), streptozotocin (50 mg/kg) and picolinamide (250 mg/kg i.p.), alloxan (40 mg/kg i.v.) and nicotinamide (350 mg/kg), alloxan (40 mg/kg) and 3-aminobenzamide (345 mg/kg), and alloxan (40 mg/kg) and picolinamide (250 mg/kg), pancreatic islet cell tumors developed in 100, 98, 60, 26, 22, and 20% of surviving rats, respectively. "

Related Drugs and Biologics

1.	Palladium
2.	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)
3.	N- methyl- 4- (4- (3- (trifluoromethyl)benzamido)phenoxy)picolinamide
4.	Niacinamide (Nicotinamide)
5.	Streptozocin (Streptozotocin)
6.	Radiopharmaceuticals
7.	Ruthenium
8.	Ligands
9.	Interferons
10.	Interferon Type I