5-thio-D-glucose

01/01/2017 - "The oxidative induction of DNA lesions in cancer cells by 5-thio-d-glucose and 6-thio-d-fructopyranose and their genotoxic effects. "
12/01/1984 - "Failure of 5-thio-D-glucose to alter cell survival in irradiated or unirradiated EMT6 tumors."
02/01/1983 - "5-Thio-D-glucose is also known to specifically kill and radiosensitize hypoxic tumor cells. "
01/01/1980 - "Tissue distribution and retention of 5-thio-D-glucose in animal tumor models."
07/01/1979 - "Biodistribution and pharmacokinetics of S-35-labeled 5-thio-D-glucose in hamsters bearing pancreatic tumors."

08/01/1980 - "In continuing our studies on the effects of preinduced hypothermia on the endurance capacities, thermoregulatory responses, and clinical chemical indices of heat injury, 10 mg of 5-thio-D-glucose (5-TG) were administered intravenously to restrained rats kept at 4 degrees C. "

09/01/2000 - "This study examined the effects of one agent, 5-thio-D-glucose (5TG) on renal hypertrophy and transforming growth factor beta1 (TGF-beta1). "

05/01/1987 - "For the present study, 5-thio-D-glucose and cis-platin were chosen for evaluation in an ocular system because they exhibit antitumour activity, and interaction with radiation, particularly in hypoxia. "

02/01/1990 - "Brain glucoprivation induced by 5-thio-D-glucose injection into the 4th ventricle did not increase feeding on orally infused milk until 30 days of age, although hyperglycemia was evoked as early as 9 days by the same treatment. "
10/01/1984 - "5-Thio-D-glucose (200 and 500 mg/kg) produced hyperglycemia and significantly retarded emptying of the pregastric pouch of hamsters. "
07/24/1981 - "If the aqueduct was obstructed and 5-thioglucose was infused into the fourth ventricle, increased feeding and hyperglycemia persisted, whereas feeding and hyperglycemia in response to lateral ventricle infusion were abolished. "
07/24/1981 - "Microinfusion of 5-thioglucose into either the lateral or fourth cerebral ventricle caused increased feeding and hyperglycemia in rats when the cerebral aqueduct was unobstructed. "
12/08/1980 - "Increased feeding and hyperglycemia elicited by intracerebroventricular 5-thioglucose."