methylformamide

10/01/1992 - "In vivo and in vitro studies performed on the polar solvent N-methylformamide (NMF), as well as on its association with chemotherapeutic agents or X rays, have clearly demonstrated that this compound is capable of inducing changes in biological characteristics of tumor cells, e.g., cell differentiation. "
05/01/1985 - "Phase I study of N-methylformamide in patients with advanced cancer."
03/01/1995 - "[A modification in the radiation reaction of normal and tumor tissues in mice induced by N-methylformamide]."
04/01/1989 - "The maturational agent N-methylformamide (NMF) is an antitumor agent that also enhances the response of tumor cells in vitro to chemotherapeutic agents. "
01/01/1989 - "[Inhibition of transplantable tumors in mice by monomethylformamide]."

12/01/1987 - "Phase I trial of N-methylformamide in pediatric patients with refractory leukemias."
01/01/1988 - "The relationship between the N-methylformamide (NMF)-induced differentiation of HL-60 human promyelocytic leukemia cells, to myeloid cells, and their proliferative potential was determined in suspension culture. "
06/01/1983 - "Although leukemia with this chromosomal abnormality has been classified as L2 acute lymphoblastic leukemia by the FAB classification, two of our cases appeared to be of myelomonocyte origin as demonstrated by cytochemical, immunologic, and electron microscopic studies and differentiation induction by 12-tetradecanoyl-phorbol-13-acetate and methylformamide. "
01/01/1987 - "Structure-activity studies of a series of polar organic compounds, including N,N-dimethylformamide, N-methylformamide, and related ureas and acetamides, were performed with regard to their ability to promote the terminal differentiation of the human promyelocytic leukemia cell line HL-60 to granulocyte-like cells. "
02/01/1987 - "The influence of sodium ascorbate, menadione sodium bisulfite or pyridoxal hydrochloride on the toxic and antineoplastic action of N-methylformamide in P 388 leukemia or M 5076 sarcoma in mice."

12/01/1987 - "Phase II study on oral N-methylformamide in metastatic colorectal cancer."
05/01/1987 - "Phase II study of N-methylformamide in patients with advanced colorectal cancer."
06/01/1986 - "Phase II trial of N-methylformamide in patients with advanced colorectal carcinoma."

01/01/2001 - "N-Methylformamide in advanced squamous cancer of the uterine cervix: an Eastern Cooperative Oncology Group phase II trial."
05/01/1990 - "Phase II study of N-methylformamide (N-MF) (NSC 3051) in patients with advanced squamous cancer of the cervix. "

02/01/1989 - "N-methylformamide (NMF) (800-1,000 mg/m2 i.v. day 1) was given to 14 patients with measurable, advanced renal cell carcinoma in this Phase II trial. "
05/01/1986 - "Phase II trial of N-methylformamide for advanced renal cell carcinoma."