imipramine N-oxide

RN given refers to parent cpd; structure

Also Known As:

5-(3-(dimethylamino)propyl)-10,11-dihydro-5H- dibenz(b,f)azepine 5-(3-N-oxide); imipramine N-oxide hydrochloride; imipramine-N-oxide; 10,11-dihydro- N,N-dimethyl-5H-dibenz(b,f)azepine-5-propanamine N-oxide

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 3-Ring Heterocyclic Compounds
    - Dibenzazepines: 4
      - Imipramine: 2067
        imipramine N-oxide: 2

Experts

1.	Chandan, Pritpal: 1 article (04/2009)
2.	Hernandez, Diana: 1 article (04/2009)
3.	Janmohamed, Azara: 1 article (04/2009)
4.	Omar, Bilal A: 1 article (04/2009)
5.	Phillips, Ian R: 1 article (04/2009)
6.	Shephard, Elizabeth A: 1 article (04/2009)

Related Diseases

1.	Depressive Disorder (Melancholia) 01/01/1973 - "Comparative trial of imipramine N-oxide and imipramine in the treatment of out-patients with depressive syndromes."
2.	Tremor (Tremors) 04/01/2009 - "In contrast, knockout mice did not produce imipramine N-oxide, but showed exaggerated pharmacological behavioural responses, such as tremor and body spasm, and had a higher concentration of the parent compound imipramine in the serum and kidney and there was an increase in desipramine in the brain. "
3.	Spasm (Spasms) 04/01/2009 - "In contrast, knockout mice did not produce imipramine N-oxide, but showed exaggerated pharmacological behavioural responses, such as tremor and body spasm, and had a higher concentration of the parent compound imipramine in the serum and kidney and there was an increase in desipramine in the brain. "

Related Drugs and Biologics

1.	Imipramine (Janimine)
2.	Desipramine (Pertofrane)