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eremanthin

Also Known As:

eremanthine

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Sesquiterpenes: 1370
      - eremanthin: 3

Experts

1.	Kong, Weimin: 1 article (05/2020)
2.	Liu, Tingting: 1 article (05/2020)
3.	Liu, Yao: 1 article (05/2020)
4.	Song, Dan: 1 article (05/2020)
5.	Zhao, Xiaoling: 1 article (05/2020)

Related Diseases

1.	Uterine Cervical Neoplasms (Cancer of the Cervix) 05/01/2020 - "Hence, the current study was designed to investigate the in vitro anticancer potency of Eremanthin against human HeLa cervical cancer cells. " 05/01/2020 - "Anticancer activity of Eremanthin against the human cervical cancer cells is due to G2/M phase cell cycle arrest, ROS-mediated necrosis-like cell death and inhibition of PI3K/AKT signalling pathway." 05/01/2020 - "Eremanthin molecule is a potent anticancer agent against human cervical cancer and may be included as lead molecule in cervical cancer treatment provided further in vitro and in vivo investigations are performed."
2.	Schistosomiasis (Bilharziasis) 11/01/1972 - "Chemoprophylactic agents in schistosomiasis: eremanthine, costunolide, -cyclocostunolide and bisabolol."
3.	Neoplasms (Cancer) 05/01/2020 - "Eremanthin exerted significant cytotoxic effects on HeLa cervival cancer cells. "
4.	Necrosis 05/01/2020 - "Eremanthin induced specific modifications in cellular morphology of HeLa cells, indicating its necrosis-mediated cytotoxicity. " 05/01/2020 - "Anticancer activity of Eremanthin against the human cervical cancer cells is due to G2/M phase cell cycle arrest, ROS-mediated necrosis-like cell death and inhibition of PI3K/AKT signalling pathway."
5.	Chromosome Aberrations (Chromosome Abnormalities) 01/01/1995 - "In the in vitro treatment of human lymphocyte cultures, eremanthine also did not cause any increase in chromosomal aberrations or sister chromatid exchanges at the following concentrations in culture medium: 1.25, 2.50, and 5.00 micrograms/ml. From these results, under our experimental conditions, neither "sucupira" oil nor eremanthine showed clastogenic effects on mammalian cells in vivo or in vitro." 01/01/1995 - "When eremanthine was tested on BALB/c mice following gavage at doses of 100, 200, and 300 mg/kg bw, it did not induce structural or numerical chromosomal aberrations. "

Related Drugs and Biologics

1.	Antineoplastic Agents (Antineoplastics)
2.	bisabolol (levomenol)
3.	cyclocostunolide
4.	costunolide