tocopherylquinone

RN refers to (3R-(3R*,7R*,11R*))-isomer; structure

Also Known As:

2 (3-hydroxy-3,7,11,15-tetramethylhexadecyl)- 3,5,6-trimethyl-1,4-benzoquinone; Eutrophyl; alpha-tocopherol quinone; alpha-tocopherolquinone; alpha-tocopheryl quinone; alpha-tocoquinone; delta-tocopherylquinone; gamma-tocopherylquinone; tocopherolquinone; tocopherylquinone, ((3R*,7R*,11R*)-(+-))-isomer; vitamin E quinone

Networked: 35 relevant articles (2 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Benzopyrans: 195
      - Vitamin E: 8680
        tocopherylquinone: 35
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzopyrans: 195
      - Vitamin E: 8680
        tocopherylquinone: 35

Experts

1.	Fajardo, Alexandra M: 1 article (01/2016)
2.	MacKenzie, Debra A: 1 article (01/2016)
3.	Olguin, Sarah L: 1 article (01/2016)
4.	Rabinowitz, Ian: 1 article (01/2016)
5.	Scariano, John K: 1 article (01/2016)
6.	Thompson, Todd A: 1 article (01/2016)
7.	Hawi, Amale: 1 article (01/2012)
8.	Heald, Sarah: 1 article (01/2012)
9.	Sciascia, Thomas: 1 article (01/2012)
10.	Aalbersberg, William: 1 article (10/2010)

Related Diseases

1.	Ulcerative Colitis 11/01/1986 - "Use of alpha-tocopherylquinone in ulcerative colitis." 06/01/1986 - "Use of alpha-tocopherylquinone in the treatment of ulcerative colitis." 06/01/1986 - "The effect of alpha-tocopherylquinone (alpha-TQ) and a low fat diet on a patient with chronic continuous ulcerative colitis was described. " 06/01/1986 - "Since the responsible bacterial reactions may be dependent on vitamin K as an electron acceptor it is suggested that poorly absorbed vitamin K antagonists, specifically alpha-tocopherylquinone, may be capable of inhibiting these reactions and may therefore prove effective in treating ulcerative colitis and in preventing the development of colon cancer."
2.	Inflammation (Inflammations) 09/15/2023 - "Alpha-tocopherylquinone-mediated activation of the Aryl Hydrocarbon Receptor regulates the production of inflammation-inducing cytokines and ameliorates intestinal inflammation."
3.	Colonic Neoplasms (Colon Cancer) 06/01/1986 - "Since the responsible bacterial reactions may be dependent on vitamin K as an electron acceptor it is suggested that poorly absorbed vitamin K antagonists, specifically alpha-tocopherylquinone, may be capable of inhibiting these reactions and may therefore prove effective in treating ulcerative colitis and in preventing the development of colon cancer."
4.	Hypertension (High Blood Pressure) 09/21/1961 - "[Trial treatment of hypertension with a new hypotensive drug (trimethyl-tetramethyl-hexadecanone-olbenzoquinone or tocopherylquinone)]." 03/31/1965 - "[CLINICAL CONSIDERATIONS ON THE USE OF TOCOPHERYLQUINONE IN THE TREATMENT OF ARTERIAL HYPERTENSION]." 11/01/1963 - "[ACTION OF TOCOPHERYLQUINONE IN ARTERIAL HYPERTENSION OF THE FIFTIES]." 01/28/1961 - "[Use of tocopherylquinone in the ambulatory therapy of arterial hypertension]."
5.	Muscular Diseases (Myopathy) 04/26/1968 - "[Clinical and biological study of the application of alpha-tocopheryl-quinone for 5 years of primary and secondary muscular diseases and for 1 case of scleroderma]."

Related Drugs and Biologics

1.	Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)
2.	Cytokines
3.	Vitamin K
4.	alpha-Tocopherol
5.	Antioxidants
6.	Vitamin E
7.	Lipids
8.	Ubiquinone
9.	Fatty Acid Desaturases
10.	Glutathione Disulfide (GSSG)

Related Therapies and Procedures

1.	Fat-Restricted Diet (Diet, Fat Restricted)
2.	Therapeutics
3.	Injections