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chymostatin

Networked: 34 relevant articles (1 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - chymostatin: 34

Experts

1.	Jonnalagadda, Sreekantha B: 1 article (11/2020)
2.	Moodley, Roshila: 1 article (11/2020)
3.	Ofusori, Adebimpe Esther: 1 article (11/2020)
4.	Dong, Xue-Song: 1 article (02/2018)
5.	Liu, Wei: 1 article (02/2018)
6.	Liu, Zhi: 1 article (02/2018)
7.	Song, Hong-Wei: 1 article (02/2018)
8.	Yang, Chen: 1 article (02/2018)
9.	Baranowska, Iwona: 1 article (09/2015)
10.	Gawryś, Olga: 1 article (09/2015)

Related Diseases

1.	Acute Lung Injury 02/01/2018 - "Protective Effects of Chymostatin on Paraquat-Induced Acute Lung Injury in Mice." 02/01/2018 - "This study aims to evaluate the role of chymostatin in paraquat-induced acute lung injury. "
2.	Carcinogenesis 07/01/1990 - "In the present study, we examined the ability of chymostatin, a highly specific inhibitor of chymotrypsin, to suppress dimethylhydrazine-induced colon carcinogenesis, and the dose-response relationship for an extract of soybeans containing the Bowman-Birk inhibitor (BBI) to suppress dimethylhydrazine-induced colon carcinogenesis, when added to the diet of mice. "
3.	Infarction (Infarctions) 10/01/1983 - "To determine whether future studies on the effects of proteolytic inhibition on infarct size are feasible, the ability of the proteinase inhibitors antipain, leupeptin, pepstatin and chymostatin, given in vivo, to interfere with proteolysis in ischemic myocardium was also evaluated. "
4.	Rupture 06/01/1983 - "Both chymostatin and leupeptin inhibited normal rupture of schizont-infected erythrocytes. " 01/01/2011 - "We used previously reported broad-spectrum inhibitors (E64d, EGTA-AM and chymostatin) to inhibit these proteases and impede rupture to analyze mechanical signatures associated with parasite escape. " 05/01/1990 - "The 190-kDa form of the protein is recovered from the cell pellet in schizont-infected erythrocytes and partitions to the soluble fraction when extracted with detergent; (4) release of soluble EBA-175 into the culture supernatant coincides with schizont rupture; (5) there was no observable change in pI (pI = 6.86) by isoelectric focusing between the cellular and supernatant species of the protein; and (6) release of EBA-175 into the culture supernatant is inhibited by the addition of chymostatin and leupeptin. "
5.	Neoplasms (Cancer) 11/01/1985 - "Using 200 microM chymostatin and low doses (25-40 microM) of the irreversible enzyme inhibitors, the antimetastatogenic effect is revealed to be specific, as primary tumor development is not affected. " 02/01/2018 - "Institute of Cancer Research mice were randomly distributed into the NS, DMSO, chymostatin, paraquat or chymostatin treatment groups. " 05/16/2008 - "Kallikrein 7 (hK7), a chymostatin-like serine protease, is overexpressed in pancreatic adenocarcinomas as well as other human cancers. "

Related Drugs and Biologics

1.	Paraquat
2.	leupeptin
3.	Peptide Hydrolases (Proteases)
4.	Chymotrypsin
5.	Antipain
6.	pepstatin (pepstatin A)
7.	Dimethylhydrazines
8.	Chymases (Chymase)
9.	Protease Inhibitors (Protease Inhibitor)
10.	Serine Proteases (Serine Protease)

Related Therapies and Procedures

1.	Estrogen Replacement Therapy