triptolide

06/01/2015 - "Triptolide, a natural compound isolated from the Chinese herb Tripterygium wilfordii, is effective against multiple cancers. "
10/01/2010 - "We recently observed that triptolide (a diterpenoid triepoxide) is effective in inducing apoptosis in pancreatic tumors. "
01/01/2012 - "Our findings will offer new strategies to develop improved triptolide analogs for cancer therapy."
10/01/2014 - "In the present study, we investigated the ability of triptolide, a diterpenoid isolated from Thunder of God Vine, to inhibit signaling by receptor activator of NF-κB (RANK) and its ligand (RANKL) and to modulate osteoclastogenesis induced by RANKL and human cancer cells. "
02/01/2013 - "Numerous studies have demonstrated that triptolide induces cell cycle arrest and apoptosis in human cancer cell lines. "

06/28/2014 - "A combination of TRAIL and the diterpene triepoxide, triptolide, is effective in inducing pancreatic cancer cell death. "
10/17/2012 - "We have previously shown that triptolide, a diterpenoid, is effective against pancreatic cancer cells in vitro as well as in vivo. "
05/01/2015 - "Triptolide, a diterpene triepoxide that was derived from a Chinese herb, has shown great promise in preclinical testing against pancreatic cancer using immunocompromised animals. "
06/01/2015 - "We have synthesized a water soluble analog of triptolide, named Minnelide, which is currently in phase I trial against pancreatic cancer. "
06/28/2014 - "Our study provides a mechanism by which triptolide sensitizes TRAIL resistant cells, which may become a novel therapeutic strategy against pancreatic cancer. "

01/01/2015 - "Retraction note: Triptolide ameliorates lipopolysaccharide-induced acute lung injury in rats."
01/01/2013 - "Triptolide ameliorates lipopolysaccharide-induced acute lung injury in rats."
12/01/2014 - "The aim of this study was to investigate the effect of triptolide on ATP‑binding cassette transporter A1 (ABCA1) expression in lipopolysaccharide (LPS)‑induced acute lung injury (ALI) in rats. "
08/01/2014 - "The aim of this study was to investigate the effects of triptolide on lipopolysaccharide (LPS)-induced acute lung injury (ALI) in mice and to clarify the possible mechanisms. "
07/01/2014 - "The aim of this study was to investigate the effects of triptolide on lipopolysaccharide (LPS)‑induced acute lung injury (ALI) in mice and to explore the possible mechanisms. "

10/01/2008 - "Triptolide, a diterpenoid isolated from the Chinese herb Tripterygium wilfordii Hook F, has been demonstrated to be effective in the treatment of a variety of autoimmune diseases. "
04/01/2010 - "This study provides mechanistic insights into the immunomodulatory capacity of triptolide and has strong implications for its therapeutic applications in autoimmune diseases."
12/01/2013 - "Triptolide (TP), a main bioactive component of Tripterygium wilfordii Hook F., is a promising agent for treatment of autoimmune diseases. "
10/01/2010 - "Triptolide has been used for treating various autoimmune diseases. "
02/01/2007 - "Triptolide (TP), a traditional Chinese medicine, has been reported to be effective in the treatment of autoimmune diseases and exerting antineoplastic activity in several human tumor cell lines. "

01/01/2010 - "To study the effect of programmed cell death 5 (PDCD5) on apoptosis of rheumatoid arthritis fibroblast-like synoviocyte (RAFLS) induced by triptolide. "
06/01/2014 - "[Triptolide inhibits the inflammatory response of monocytes from rheumatoid arthritis patients by regulating miR-155]."
01/01/2013 - "Anti-angiogenic effect of triptolide in rheumatoid arthritis by targeting angiogenic cascade."
06/01/2012 - "Triptolide (TP) has been used in the treatment of rheumatoid arthritis (RA), but its mechanism of action is not understood. "
01/01/2010 - "Programmed cell death 5 factor enhances triptolide-induced fibroblast-like synoviocyte apoptosis of rheumatoid arthritis."