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tripdiolide

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structure

Also Known As:

NSC-163063; (2 beta)-2-hydroxytriptolide

Networked: 2 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 58
- Hydrocarbons: 412
  - Terpenes: 260
    - Diterpenes: 237
      - tripdiolide: 2

Experts

1.	Matławska, Irena: 1 article (08/2012)
2.	Grzegorzewska, Alicja E: 1 article (08/2012)
3.	Frankiewicz, Dorota: 1 article (08/2012)
4.	Bylka, Wiesława: 1 article (08/2012)
5.	Bręborowicz, Danuta: 1 article (08/2012)
6.	Fan, Fred: 1 article (06/2008)
7.	Gao, Chun Y: 1 article (06/2008)
8.	Longo, Nancy S: 1 article (06/2008)
9.	Zerfas, Patricia: 1 article (06/2008)
10.	Hoffmann, Victoria: 1 article (06/2008)

Related Diseases

1.	Lupus Nephritis 06/01/2008 - "Triptolide and tripdiolide are thought to be active components of the Chinese antirheumatic herbal remedy Tripterygium wilfordii Hook F, which has been shown to be effective in treating murine lupus nephritis. " 06/01/2008 - "This study was undertaken to examine the therapeutic effect of triptolide and tripdiolide on established lupus nephritis in (NZB x NZW)F1 mice. " 06/01/2008 - "Therapy with triptolide or tripdiolide significantly ameliorated lupus nephritis in (NZB x NZW)F1 mice, reduced cytokine and chemokine production, and prolonged survival." 06/01/2008 - "(NZB x NZW)F1 mice were treated with vehicle, triptolide, or tripdiolide for 15 weeks beginning at the age of 29 weeks (after the development of lupus nephritis). "
2.	Kaposi Sarcoma (Kaposi's Sarcoma) 08/01/2012 - "Triptolide/tripdiolide could contribute to development of Kaposi sarcoma by reactivation of latent human herpesvirus 8, permitted by immunosuppression induced by triptolide." 08/01/2012 - "This case indicates a possible association between triptolide/tripdiolide chronic intake and development of human herpesvirus 8-associated Kaposi sarcoma. " 08/01/2012 - "Disseminated cutaneous Kaposi sarcoma in a patient receiving triptolide/tripdiolide for rheumatoid arthritis." 08/01/2012 - "To date, Kaposi sarcoma has not been mentioned among the adverse effects of triptolide/tripdiolide, ethyl acetate extracts or polyglycosides of the Chinese herbal remedy Tripterygium wilfordii Hook F. "
3.	Proteinuria 06/01/2008 - "In contrast, proteinuria and BUN levels were significantly reduced in mice treated with either triptolide or tripdiolide as compared with those treated with vehicle. "
4.	Nephritis 06/01/2008 - "Effective therapy for nephritis in (NZB x NZW)F1 mice with triptolide and tripdiolide, the principal active components of the Chinese herbal remedy Tripterygium wilfordii Hook F."
5.	Rheumatoid Arthritis 08/01/2012 - "Disseminated cutaneous Kaposi sarcoma in a patient receiving triptolide/tripdiolide for rheumatoid arthritis."

Related Drugs and Biologics

1.	triptolide
2.	ethyl acetate