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2- ethyl- 8- methyl- 2,8- diazaspiro(4,5)decane- 1,3- dione (RS 86)

RN given refers to parent cpd
Also Known As:
RS 86; 2-ethyl-8-methyl-2,8-diazaspiro(4,5)decane-1,3-dione fumarate; 2-ethyl-8-methyl-2,8-diazaspiro(4,5)decane-1,3-dione fumarate (2:1); 2-ethyl-8-methyl-2,8-diazaspiro(4,5)decane-1,3-dione hydrobromide; 2-ethyl-8-methyl-2,8-diazaspiro(4,5)decane-1,3-dione hydrochloride; 2-ethyl-8-methyl-2,8-diazaspiro(4,5)decane-1,3-dione monofumarate; 2-ethyl-8-methyl-2,8-diazaspiro(4,5)decane-1,3-dione monohydrobromide; RS-86; spiro-(N'-methylpiperidyl-4')-N-ethylsuccinimide fumarate
Networked: 26 relevant articles (3 outcomes, 6 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Soares-Weiser, Karla: 2 articles (01/2018 - 11/2004)
2. McGrath, J J: 2 articles (01/2002 - 01/2000)
3. Baksh, Brandon S: 1 article (01/2022)
4. Felix, Elizabeth: 1 article (01/2022)
5. Galor, Anat: 1 article (01/2022)
6. Karp, Carol L: 1 article (01/2022)
7. Morkin, Melina: 1 article (01/2022)
8. Asher, Rosie: 1 article (01/2018)
9. Bergman, Hanna: 1 article (01/2018)
10. Tammenmaa-Aho, Irina: 1 article (01/2018)

Related Diseases

1. Schizophrenia (Dementia Praecox)
2. Tardive Dyskinesia
3. Mental Disorders (Mental Disorder)
07/01/1992 - "The influence of the cholinergic agonist RS 86 on electroencephalographic (EEG) sleep was investigated in 21 healthy members of families identified as being at high risk for psychiatric disorders and in 17 healthy control subjects without any personal or family history of a psychiatric illness. "
05/01/1992 - "Comparative studies with the cholinergic agonist RS 86 in depressed patients, schizophrenic patients and patients with other psychiatric disorders revealed the most pronounced REM sleep response in the depressed group. "
01/01/2000 - "To determine whether the use of cholinergic agents (arecoline, choline, deanol, lecithin, meclofenoxate, physostigmine, RS 86) were associated with clinical improvement in neuroleptic-induced TD in people with schizophrenia or other chronic mental illnesses. "
01/01/2018 - "To determine the effects of cholinergic drugs (arecoline, choline, deanol, lecithin, meclofenoxate, physostigmine, RS 86, tacrine, metoxytacrine, galantamine, ipidacrine, donepezil, rivastigmine, eptastigmine, metrifonate, xanomeline, cevimeline) for treating antipsychotic-induced TD in people with schizophrenia or other chronic mental illness. "
01/01/2002 - "To determine the effects of cholinergic drugs (arecoline, choline, deanol, lecithin, meclofenoxate, physostigmine, RS 86, tacrine, metoxytacrine, galantamine, ipidacrine, donepezil, rivastigmine, eptastigmine, metrifonate, xanomeline, cevimeline) for treating neuroleptic-induced tardive dyskinesia in people with schizophrenia or other chronic mental illness. "
4. Dementia (Dementias)
5. Alzheimer Disease (Alzheimer's Disease)

Related Drugs and Biologics

1. Cholinergic Agents (Cholinergics)
2. Physostigmine
3. Arecoline (Arecolin)
4. Lecithins
5. Antipsychotic Agents (Antipsychotics)
6. Deanol (Dimethylethanolamine)
7. Choline (Choline Chloride)
8. Meclofenoxate (Centrophenoxine)
9. Muscarinic Agonists
10. Trichlorfon (Metrifonate)

Related Therapies and Procedures

1. Analgesia