C 684

RN given refers to parent cpd; structure in second source

Also Known As:

1-nitro-9-(3-dimethylaminopropylamino)acridine N-10-oxide; 1-nitro-9-(dimethylaminopropylamino)acridine N-oxide; C 666; C-666; C-684; SN 24030; SN-24030; VAN of C 684; di-HCl of C 684; nitracrine N-oxide; 1,3-propanediamine, N,N-dimethyl-N'-(1-nitro-9-acridinyl)-, N-oxide

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 3-Ring Heterocyclic Compounds
    - Acridines: 325
      - Aminoacridines: 3
        Nitracrine: 46
        C 684: 4

Experts

1.	Li, Tianjiao: 2 articles (10/2021 - 01/2020)
2.	Luo, Mingyao: 2 articles (10/2021 - 01/2020)
3.	Ma, Baihui: 2 articles (10/2021 - 01/2020)
4.	Shu, Chang: 2 articles (10/2021 - 01/2020)
5.	Yang, Hang: 2 articles (10/2021 - 01/2020)
6.	Zhou, Zhou: 2 articles (10/2021 - 01/2020)
7.	Zhu, Guoyan: 1 article (10/2021)
8.	Chen, Guokai: 1 article (01/2020)
9.	Liu, Weiwei: 1 article (01/2020)
10.	Xu, Faxiang: 1 article (01/2020)

Related Diseases

1.	Marfan Syndrome (Marfan's Syndrome) 10/01/2021 - "Patient-specific hiPSCs (NCCDFWi001-A) were generated from a patient with Marfan syndrome carrying a compound heterozygous variant (c.684_736 + 4del, p.Pro228fs and c.2613A>C, p.Leu871Phe). " 01/01/2020 - "The human induced pluripotent stem cell line NCCDFWi001-A was derived from peripheral blood mononuclear cells (PBMC) of a 26-year-old female Marfan syndrome patient carrying two compound heterozygous variants FBN1c.2613A > C, (p.Leu871Phe) and c.684_736 + 4del. " 01/01/2020 - "Generation of a human induced pluripotent stem cell line (NCCDFWi001-A) from a Marfan syndrome patient carrying two FBN1 variants (c.2613A > C and c.684_736 + 4del)."
2.	Hypoxia (Hypoxemia) 06/21/1996 - "A series of nuclear-substituted derivatives of nitracrine N-oxide (2; a bis-bioreductive hypoxia-selective cytotoxin) were prepared and evaluated, seeking analogues of lower nitroacridine reduction potential. " 06/21/1996 - "Effects of acridine substitution on the hypoxia-selective cytotoxicity and metabolic reduction of the bis-bioreductive agent nitracrine N-oxide." 01/01/1992 - "Bis-bioreductive agents as hypoxia-selective cytotoxins: nitracrine N-oxide."

Related Drugs and Biologics

1.	Cytotoxins (Cytolysins)
2.	Acridines