HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

menoctone

Also Known As:

2-(8-cyclohexyloctyl)-3-hydroxy-1,4-naphthoquinone; WR 9808; Win 11,530

Networked: 6 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Naphthalenes: 18
        Naphthoquinones: 418
        menoctone: 6
- Quinones: 434
  - Naphthoquinones: 418
    - menoctone: 6
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Naphthalenes: 18
    - Naphthoquinones: 418
      - menoctone: 6

Experts

1.	Blake, Lynn D: 1 article (01/2017)
2.	Iyamu, Iredia D: 1 article (01/2017)
3.	Johnson, Myles E: 1 article (01/2017)
4.	Kyle, Dennis E: 1 article (01/2017)
5.	Manetsch, Roman: 1 article (01/2017)
6.	McQueen, Adonis: 1 article (01/2017)
7.	Shaikh, Abdul Kadar: 1 article (01/2017)
8.	Shultis, Michael W: 1 article (01/2017)
9.	Siegel, Sasha V: 1 article (01/2017)

Related Diseases

1.	Theileriasis 11/01/1981 - "The i/m route was slightly more effective than i/v. The p/o administration of menoctone had only a slight and transient beneficial effect and 10 cattle treated by this route all died of theileriosis. " 11/01/1981 - "Treatment of stabilate-induced East Coast fever with menoctone." 11/01/1983 - "Ten naphthoquinones, including parvaquone (993C) (Clexon; Wellcome) and menoctone, were tested for activity in cattle artificially infected with Theileria parva, the causative organism of East Coast fever (ECF). "
2.	Malaria 01/01/2017 - "Menoctone Resistance in Malaria Parasites Is Conferred by M133I Mutations in Cytochrome b That Are Transmissible through Mosquitoes." 02/01/1979 - "However, since malarial ubiquinones are apparently different from those in the mammal and since menoctone, which is active in vivo in experimental malaria, is a good inhibitor of the malarial enzyme, it could represent a useful target for chemotherapeutic attack. "
3.	Body Weight (Weight, Body) 11/01/1981 - "The disease was rapidly controlled and all the treated cattle (15) recovered following (i/v) or i/m injection of a single dose of menoctone at 10 mg/kg body weight but control was incomplete with lower dosages in single or multiple dose regimens. " 02/01/1992 - "Minimum effective doses (mg base drug/kg of mouse body weight) that prevented mosquitoes from developing sporozoite-infected salivary glands were 0.1563 mg/kg for WR-250547, 0.625 mg/kg for menoctone, 1.25 mg/kg for primaquine, 10 mg/kg for floxacrine, 10 mg/kg for WR-242511, 10 mg/kg for WR-250548, and 25 mg/kg for WR-238605."
4.	Infections 12/01/1968 - "Causal prophylactic effect of Menoctone (a new hydroxynaphthoquinone) against sporozoite-induced Plasmodium berghei infection in mice."

Related Drugs and Biologics

1.	Cytochromes b (Cytochrome b)
2.	Primaquine
3.	Naphthoquinones
4.	Enzymes
5.	Dihydrotachysterol (AT 10)
6.	WR 242511
7.	tafenoquine
8.	parvaquone (993C)
9.	floxacrine