marmesin

01/01/2022 - "The study aimed to explore the anti-cancer role of marmesin using EC cell lines in vitro. "
01/01/2022 - "Marmesin exerted anti-cancer activity in EC cells by inhibiting the PI3K/Akt pathway."
05/01/2019 - "The effects of the Nodakenetin were also investigated in vivo in xenografted mice models and it was found that this molecule could inhibit the growth of xenografted tumors. "
02/01/2018 - "Remarkably, marmesin prevent tumor growth significantly in vivo at the dosage of 30 mg/kg in vivo. "
01/01/2017 - "Collectively, these findings demonstrate the pharmacological roles and molecular targets of marmesin in regulating NSCLC cell responses and tumor angiogenesis."

05/01/2019 - "These results indicate Nodakenetin significantly inhibits the growth of leukemia cells in vitro and in vivo and may be a valuable molecule in the management of leukemia, and as such needs further in depth investigations."
05/01/2019 - "It was also observed that Nodakenetin could inhibit the migration and invasion of the leukemia cells in a concentration-dependent manner. "
05/01/2019 - "Nodakenetin could significantly inhibit the proliferation of the all the leukemia cells. "
05/01/2019 - "In vitro and in vivo growth inhibition of human leukemia cells by Nodakenetin are mediated via mitochondrial apoptosis, cell cycle arrest and inhibition of cell migration and invasion."
02/01/2018 - "These results strongly indicate that marmesin may prove to be a novel anticancer lead for the management of leukemia."

05/01/2019 - "To study the anticancer potential of a plant-derived coumarin, Nodakenetin, against acute lymphocytic leukemia HL-60 cells. "

01/01/2017 - "In the present study, we investigated the effects and molecular mechanism of marmesin, a natural coumarin compound isolated from Broussonetia kazinoki, on non-small cell lung cancer (NSCLC) cell responses and tumor angiogenesis. "
01/01/2017 - "Marmesin-mediated suppression of VEGF/VEGFR and integrin β1 expression: Its implication in non-small cell lung cancer cell responses and tumor angiogenesis."

01/01/2023 - "Our previous studies have shown that bael fruit extract, containing marmesin and marmelosin, inhibits the HSULF-2 activity and kills breast tumor cells, but the mechanism of these processes remains fairly known mainly because the HSULF-2's 3D structure is partially known. "