lotaustralin

higher homologue of linamarin from flax; a cyanogenic glycoside; RN given refers to (R)-isomer; structure

Also Known As:

2(R)-hydroxy-2-methylbutyronitrile-beta-D- glucopyranoside; lotaustralin, (S)-isomer

Networked: 6 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Rivadeneyra-Domínguez, Eduardo: 3 articles (01/2020 - 09/2013)
2.	Rodríguez-Landa, Juan Francisco: 3 articles (01/2020 - 09/2013)
3.	Díaz-Sobac, Rafael: 2 articles (09/2019 - 09/2013)
4.	Vázquez-Luna, Alma: 2 articles (09/2019 - 09/2013)
5.	Hernandez-Baltazar, Daniel: 1 article (01/2020)
6.	León-Chávez, Bertha Alicia: 1 article (01/2020)
7.	Nadella, Rasajna: 1 article (01/2020)
8.	Rembao-Bojórquez, Daniel: 1 article (01/2020)
9.	Rivadeneyra-Domínguez, E: 1 article (01/2020)
10.	Rodríguez-Landa, J F: 1 article (01/2020)

Related Diseases

1.	Nervous System Diseases (Neurological Disorders) 01/01/2020 - "Cassava (Manihot esculenta Crantz) contains cyanogenic glycosides (linamarin and lotaustralin) that have been associated with neurological disorders in humans and rats. " 01/01/2020 - "However, cassava contains cyanogenic glycosides, such as linamarin and lotaustralin, that can trigger severe toxic effects and some neurological disorders, including motor impairment, cognitive deterioration, and symptoms that characterize tropical ataxic neuropathy and spastic epidemic paraparesis (Konzo). "
2.	Neoplasms (Cancer) 08/15/2023 - "Cassava (Manihot esculenta Crantz) contains cyanogenic glycosides such as, linamarin and lotaustralin, can be enzymatically cleaved by linamarase to release hydrogen cyanide (HCN), which can have therapeutic benefits against hypertension, asthma, and cancer. " 01/01/2020 - "Other substances in these groups with pronounced biological activity (including anti-tumor) are the hydrolyzed nitrile groups by Prunasin, Lucumin, Vicianin, Sambunigrin, Dhurrin, Taxiphyllin, Zierin, Preteacin, p-Glucosyloxymandelonitrile, Linamarin, Lotaustralin, Acaciapetalin, Triglochinin, Dejdaclin, Tetraphyllin A, Tetrallin B, Gynocardin etc., to their amide/carboxylic acid."
3.	Cognitive Dysfunction 01/01/2020 - "However, cassava contains cyanogenic glycosides, such as linamarin and lotaustralin, that can trigger severe toxic effects and some neurological disorders, including motor impairment, cognitive deterioration, and symptoms that characterize tropical ataxic neuropathy and spastic epidemic paraparesis (Konzo). "
4.	Malnutrition (Nutritional Deficiencies) 09/01/2013 - "However, if it is not adequately processed or the consumer has nutritional deficiencies, then its cyanogenic glycoside (i.e., linamarin and lotaustralin) content makes it potentially neurotoxic. "
5.	Paraparesis 01/01/2020 - "However, cassava contains cyanogenic glycosides, such as linamarin and lotaustralin, that can trigger severe toxic effects and some neurological disorders, including motor impairment, cognitive deterioration, and symptoms that characterize tropical ataxic neuropathy and spastic epidemic paraparesis (Konzo). "

Related Drugs and Biologics

1.	linamarin
2.	cyanogenic glycosides
3.	Nitriles
4.	Hydrogen Cyanide (Zyklon B)
5.	Glycosides
6.	Glucosides
7.	Enzymes
8.	Carboxylic Acids
9.	Amides
10.	6-O-arabinopyranosylglucopyranoside