Innovar

combination drug containing fentanyl citrate & droperidol

Also Known As:

Innovar-Vet; Thalamonal; fentanyl-droperidol; leptofen; talamonal; N-phenyl-N-(1-(2-phenylethyl)-4-piperidinyl)propanamide. 2-hydroxy-1,2,3-propanetricarboxylate mixt. with 1-(1-(4-(4-fluorophenyl)-4-oxobutyl)-1,2,3,6- tetrahydro-4-pyridinyl)-1,3-dihydro-2H-benzimidazol- 2-one

Networked: 70 relevant articles (1 outcomes, 4 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1.	Drion, Pierre: 1 article (11/2013)
2.	Sandersen, Charlotte: 1 article (11/2013)
3.	Serteyn, Didier: 1 article (11/2013)
4.	Sonea, Alexandru: 1 article (11/2013)
5.	Tutunaru, Alexandru C: 1 article (11/2013)
6.	Reinsfelt, B: 1 article (01/2011)
7.	Ricksten, S-E: 1 article (01/2011)
8.	Westerlind, A: 1 article (01/2011)
9.	Baudelet, Christine: 1 article (09/2004)
10.	Gallez, Bernard: 1 article (09/2004)

Related Diseases

1.	Vomiting 07/01/1976 - "Innovar appeared to be effective in the amelioration of vomiting although the population was too small to demonstrate statistical significance in this regard. " 03/01/1997 - "Emesis rate in the acetaminophen group was 9%, and the fentanyl-droperidol group was 13% (not statistically significant). " 03/01/1997 - "A prospective, comparative, randomized study to assess rectal acetaminophen (n = 45) to intravenous fentanyl-droperidol (n = 45) to resolve recovery profile, emesis rate, and adequacy of analgesia in a pediatric strabismus repair population was performed, with standardization of the anesthetic technique. "
2.	Vertigo (Positional Vertigo) 03/01/1999 - "Patients with intractable vertigo due to clinical Meniere's disease were offered treatment with Innovar, a neurolept analgesic. " 07/01/1976 - "Innovar administered in a single dose (droperidol 5 mg, fentanyl 0.1 mg) to patients undergoing acute episodes of vestibular disease (vestibular neuronitis and Ménière's disease) was found effective in the following symptoms and/or signs: nausea, vertigo, nystagmus, the positive past-pointing test and the Romberg test. "
3.	Meniere Disease (Menieres Disease) 03/01/1999 - "Innovar treatment for Meniere's disease." 07/01/1976 - "This mixture (also called Innovar) is rapid in action and results in complete suppression of vestibular activity of both normal subjects and those with Ménière's disease as described by Dowdy, et al., in a preliminary report. " 03/01/1999 - "Innovar is a safe, cost-effective second-line therapy for patients with Meniere's disease who have failed conventional first-line medical therapy." 03/01/1999 - "Patients with intractable vertigo due to clinical Meniere's disease were offered treatment with Innovar, a neurolept analgesic. " 07/01/1976 - "Innovar administered in a single dose (droperidol 5 mg, fentanyl 0.1 mg) to patients undergoing acute episodes of vestibular disease (vestibular neuronitis and Ménière's disease) was found effective in the following symptoms and/or signs: nausea, vertigo, nystagmus, the positive past-pointing test and the Romberg test. "
4.	Vestibular Neuronitis (Vestibular Neuritis) 07/01/1976 - "Innovar administered in a single dose (droperidol 5 mg, fentanyl 0.1 mg) to patients undergoing acute episodes of vestibular disease (vestibular neuronitis and Ménière's disease) was found effective in the following symptoms and/or signs: nausea, vertigo, nystagmus, the positive past-pointing test and the Romberg test. "
5.	Vestibular Diseases 07/01/1976 - "Since the above findings confirmed the marked effectiveness of the fentanyl-droperidol mixture in the management of vestibular disease, it was decided to determine the relative effectiveness of the droperidol component alone and this was determined by comparing the effectiveness of the drug with placebo in a double-blind study. " 07/01/1976 - "Innovar administered in a single dose (droperidol 5 mg, fentanyl 0.1 mg) to patients undergoing acute episodes of vestibular disease (vestibular neuronitis and Ménière's disease) was found effective in the following symptoms and/or signs: nausea, vertigo, nystagmus, the positive past-pointing test and the Romberg test. "

Related Drugs and Biologics

1.	Fentanyl (Sublimaze)
2.	Droperidol
3.	Pentobarbital (Nembutal)
4.	Anesthetics (Anesthetic Agents)
5.	Nifedipine (Adalat)
6.	Acetaminophen (Paracetamol)
7.	Ketamine
8.	Xylazine (Xylazin)
9.	Atropine
10.	Nitrous Oxide (Laughing Gas)

Related Therapies and Procedures

1.	Analgesia
2.	Anesthesia
3.	Therapeutics
4.	Premedication
5.	Neuroleptanalgesia