2-amino-4-methoxy-3-butenoic acid

bacterial toxin isolated from Pseudomonas aeruginosa; RN given refers to (S-(E))-isomer

Also Known As:

2-amino-4-methoxy-3-butenoic acid, (E)-isomer; L-2-amino-4-methoxy-trans-3-butenoic acid

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

1.	Carcinosarcoma 02/15/1980 - "The effect of the methionine antagonist L-2-amino-4-methoxy-trans-3-butenoic acid on the growth and metabolism of Walker carcinosarcoma in vitro."
2.	Carcinoma (Carcinomatosis) 02/01/1981 - "The tumour growth inhibitor L-2-amino-4-methoxy-trans-3-butenoic acid (Ro07-7957) inhibits serine hydroxymethyltransferase in cytosolic extracts of Walker carcinoma non-competitively with respect to L-serine with an apparent inhibition constant similar to the Km-value for L-serine. "

1.	Glycine Hydroxymethyltransferase (Serine Hydroxymethyltransferase)
2.	Serine (L-Serine)
3.	Methionine (L-Methionine)
4.	Growth Inhibitors