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Daling Zhu Selected Research

15-hydroxy-5,8,11,13-eicosatetraenoic acid

5/2015STAT3-mediated MMP-2 expression is required for 15-HETE-induced vascular adventitial fibroblast migration.
1/2015PGC-1α plays a major role in the anti-apoptotic effect of 15-HETE in pulmonary artery endothelial cells.
1/2015Modulation of Pulmonary Vascular Remodeling in Hypoxia: Role of 15-LOX-2/15-HETE-MAPKs Pathway.
8/2014NFATc3 pathway participates in the process that 15-LO/15-HETE protects pulmonary artery smooth muscle cells against apoptosis during hypoxia.
2/201415-LO/15-HETE mediated vascular adventitia fibrosis via p38 MAPK-dependent TGF-β.
9/2013Placenta growth factor mediates angiogenesis in hypoxic pulmonary hypertension.
6/201315-lipoxygenase-1/15-hydroxyeicosatetraenoic acid promotes hepatocellular cancer cells growth through protein kinase B and heat shock protein 90 complex activation.
5/201315-Lipoxygenase promotes chronic hypoxia-induced pulmonary artery inflammation via positive interaction with nuclear factor-κB.
1/2013Positive feedback-loop of telomerase reverse transcriptase and 15-lipoxygenase-2 promotes pulmonary hypertension.
12/2012Reciprocal regulation of HIF-1α and 15-LO/15-HETE promotes anti-apoptosis process in pulmonary artery smooth muscle cells during hypoxia.
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Daling Zhu Research Topics

Disease

41Anoxia (Hypoxia)
09/2015 - 05/2003
13Pulmonary Hypertension (Ayerza Syndrome)
09/2015 - 02/2011
5Neoplasms (Cancer)
06/2013 - 03/2008
3Hypertrophy
02/2014 - 10/2011
3Hypertension (High Blood Pressure)
01/2012 - 01/2008
2Premature Birth (Birth, Premature)
03/2015 - 07/2014
2Fibrosis (Cirrhosis)
02/2014 - 07/2003
2Pathologic Processes
08/2013 - 12/2012
2Inflammation
05/2013 - 01/2007
2Ovarian Neoplasms (Ovarian Cancer)
01/2010 - 11/2009
1Thrombosis (Thrombus)
09/2015
1Heart Failure
09/2015
1Neointima
05/2015
1Birth Weight (Birth Weights)
01/2015
1Pulmonary Fibrosis (Hamman Rich Syndrome)
02/2014
1Pathologic Neovascularization
09/2013
1Hepatocellular Carcinoma (Hepatoma)
06/2013
1Neoplasm Metastasis (Metastasis)
06/2013
1Arteritis
05/2013
1Vascular System Injuries
01/2013
1Hyperglycemia
11/2012
1Diabetes Mellitus
11/2012
1Wounds and Injuries (Trauma)
11/2012
1Diabetes Complications
11/2012
1Rare Diseases (Rare Disease)
05/2012
1Asthma (Bronchial Asthma)
03/2012
1Cough
03/2012
1Pre-Eclampsia (Preeclampsia)
01/2012
1Sepsis (Septicemia)
01/2012
1Acute Lung Injury
04/2011

Drug/Important Bio-Agent (IBA)

2515-hydroxy-5,8,11,13-eicosatetraenoic acidIBA
05/2015 - 05/2003
23Arachidonate 15-Lipoxygenase (Arachidonate 15 Lipoxygenase)IBA
09/2015 - 05/2003
16Hydroxyeicosatetraenoic Acids (HETE)IBA
09/2015 - 06/2008
8Small Interfering RNA (siRNA)IBA
07/2015 - 01/2010
7Idiopathic pulmonary hypertensionIBA
09/2015 - 05/2012
6Bromodeoxyuridine (BrdU)IBA
07/2015 - 10/2011
5Arachidonic Acid (Vitamin F)IBA
05/2013 - 06/2008
4Proliferating Cell Nuclear Antigen (PCNA)IBA
08/2015 - 08/2012
4DNA (Deoxyribonucleic Acid)IBA
08/2015 - 11/2012
3Nordihydroguaiaretic Acid (Masoprocol)FDA Link
09/2015 - 01/2010
3Phosphotransferases (Kinase)IBA
01/2015 - 02/2011
3OxygenIBA
05/2013 - 04/2011
3CalciumIBA
05/2012 - 08/2010
2Cyclin AIBA
07/2015 - 11/2012
2p38 Mitogen-Activated Protein KinasesIBA
01/2015 - 02/2014
2PPAR gammaIBA
01/2015 - 08/2012
2Annexin A5IBA
08/2014 - 05/2009
2Transcription Factors (Transcription Factor)IBA
08/2014 - 08/2012
215-hydroxyprostaglandin dehydrogenaseIBA
07/2014 - 07/2014
2Messenger RNA (mRNA)IBA
08/2013 - 01/2009
2IsoenzymesIBA
01/2012 - 01/2009
2Estrogen Receptor alphaIBA
11/2009 - 01/2007
1Dynamins (Dynamin)IBA
09/2015
1bindaritIBA
09/2015
1Chemokine CXCL12IBA
08/2015
1JM 3100FDA Link
08/2015
1CXCR ReceptorsIBA
08/2015
1Cyclin DIBA
07/2015
1Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA
07/2015
1TubulinIBA
07/2015
1Particulate MatterIBA
03/2015
1CoalIBA
01/2015
1Mitogen-Activated Protein KinasesIBA
01/2015
1transcription factor NF-AT c3IBA
08/2014
1Protein Isoforms (Isoforms)IBA
08/2014
1ChromatinIBA
08/2014
1Tobacco Smoke Pollution (Passive Smoking)IBA
07/2014
115-keto-5,8,11,13-eicosatetraenoic acidIBA
07/2014
1tebufenozide (Mimic)IBA
06/2014
1Fibronectins (Fibronectin)IBA
02/2014
1CollagenIBA
02/2014
1placenta growth factorIBA
09/2013
1BilirubinIBA
08/2013
1biliverdin reductaseIBA
08/2013
1Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA
06/2013
1Lipoxygenase (Lipoxygenase-1)IBA
06/2013
1Heat-Shock Proteins (Heat-Shock Protein)IBA
06/2013
1Cell Adhesion MoleculesIBA
05/2013
1Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA
05/2013
1Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA
05/2013
1Heme Oxygenase-1IBA
05/2013
1MonocrotalineIBA
01/2013
1Telomerase (Telomerase Reverse Transcriptase)IBA
01/2013
1Pyruvaldehyde (Methylglyoxal)IBA
11/2012
1Proteins (Proteins, Gene)IBA
11/2012
1LipidsIBA
11/2012
1imatinib (Gleevec)FDA Link
10/2012
1platelet-derived growth factor BB (becaplermin)FDA Link
10/2012
1Platelet-Derived Growth FactorIBA
10/2012
1TGF-beta type I receptorIBA
07/2012
1MicroRNAs (MicroRNA)IBA
05/2012
1Insulin (Novolin)FDA Link
05/2012
1LuciferasesIBA
05/2012
1Theophylline (Theon)FDA LinkGeneric
03/2012
1Cytochrome P-450 CYP1A2 (CYP1A2)IBA
03/2012
1TabletsIBA
03/2012
1Protein Kinases (Protein Kinase)IBA
01/2012
1tanshinoneIBA
01/2012
1Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
01/2012
1rho-Associated KinasesIBA
10/2011