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Anatoly Zhitkovich Selected Research

chromium hexavalent ion

10/2013Chromium(VI) causes interstrand DNA cross-linking in vitro but shows no hypersensitivity in cross-link repair-deficient human cells.
7/2012Undetectable role of oxidative DNA damage in cell cycle, cytotoxic and clastogenic effects of Cr(VI) in human lung cells with restored ascorbate levels.
6/2012Metabolism of Cr(VI) by ascorbate but not glutathione is a low oxidant-generating process.
10/2011Chromium in drinking water: sources, metabolism, and cancer risks.
2/2009Rapid DNA double-strand breaks resulting from processing of Cr-DNA cross-links by both MutS dimers.
1/2008Genetic and epigenetic mechanisms in metal carcinogenesis and cocarcinogenesis: nickel, arsenic, and chromium.
7/2007Cellular vitamin C increases chromate toxicity via a death program requiring mismatch repair but not p53.
1/2007Ascorbate acts as a highly potent inducer of chromate mutagenesis and clastogenesis: linkage to DNA breaks in G2 phase by mismatch repair.
11/2006Lower mutagenicity but higher stability of Cr-DNA adducts formed during gradual chromate activation with ascorbate.
5/2005Mismatch repair proteins are activators of toxic responses to chromium-DNA damage.

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Anatoly Zhitkovich Research Topics

Disease

8Neoplasms (Cancer)
11/2015 - 08/2005
5Anoxia (Hypoxia)
12/2013 - 09/2004
4Chromosome Breakage
10/2011 - 01/2007
3Hypersensitivity (Allergy)
10/2013 - 06/2012
3Lung Neoplasms (Lung Cancer)
07/2007 - 05/2005
1Necrosis
12/2013
1Drug Toxicity (Drug Safety)
12/2013
1Stomach Neoplasms (Stomach Cancer)
10/2011
1Cocarcinogenesis
01/2008
1Microsatellite Instability
05/2005

Drug/Important Bio-Agent (IBA)

10chromium hexavalent ionIBA
10/2013 - 05/2005
5NickelIBA
12/2013 - 09/2004
5DNA (Deoxyribonucleic Acid)IBA
10/2013 - 02/2009
3CarcinogensIBA
07/2012 - 07/2010
3ChromiumIBA
10/2011 - 08/2005
21,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA
01/2015 - 02/2009
2CobaltIBA
12/2013 - 09/2004
2Transcription Factors (Transcription Factor)IBA
11/2011 - 09/2004
1Cisplatin (Platino)FDA LinkGeneric
11/2015
1EuchromatinIBA
01/2015
1Reactive Oxygen Species (Oxygen Radicals)IBA
12/2013
1IonsIBA
12/2013
1CaspasesIBA
12/2013
1Carbon MonoxideIBA
12/2013
1Acetylcysteine (Siran)FDA LinkGeneric
12/2013
1tebufenozide (Mimic)IBA
06/2013
1methoxyamineIBA
06/2012
1DNA AdductsIBA
10/2011
1Crocidolite Asbestos (Blue Asbestos)IBA
12/2010
1ArsenicIBA
01/2008
1N-methylsuccinimideIBA
07/2007
1OxygenIBA
04/2006
1Carbonic Anhydrases (Carbonic Anhydrase)IBA
04/2006
1Proteins (Proteins, Gene)IBA
04/2006