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John H Zhang Selected Research

Ligation

1/2016Osteopontin-Rac1 on Blood-Brain Barrier Stability Following Rodent Neonatal Hypoxia-Ischemia.
10/2015G-CSF attenuates neuroinflammation and stabilizes the blood-brain barrier via the PI3K/Akt/GSK-3β signaling pathway following neonatal hypoxia-ischemia in rats.
1/2015G-CSF ameliorates neuronal apoptosis through GSK-3β inhibition in neonatal hypoxia-ischemia in rats.
9/2014Anti-neutrophil antibody enhances the neuroprotective effects of G-CSF by decreasing number of neutrophils in hypoxic ischemic neonatal rat model.
4/2013Granulocyte-colony stimulating factor in combination with stem cell factor confers greater neuroprotection after hypoxic-ischemic brain damage in the neonatal rats than a solitary treatment.
7/2012Role of the pituitary–adrenal axis in granulocyte-colony stimulating factor-induced neuroprotection against hypoxia–ischemia in neonatal rats.
9/2011Prolonged exposure to isoflurane ameliorates infarction severity in the rat pup model of neonatal hypoxia-ischemia.
3/2011Osteopontin reduced hypoxia-ischemia neonatal brain injury by suppression of apoptosis in a rat pup model.
2/2011Remote limb ischemic postconditioning protects against neonatal hypoxic-ischemic brain injury in rat pups by the opioid receptor/Akt pathway.
1/2011Capsaicin pre-treatment provides neurovascular protection against neonatal hypoxic-ischemic brain injury in rats.
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John H Zhang Research Topics

Disease

113Brain Injuries (Brain Injury)
01/2016 - 09/2002
74Brain Edema (Cerebral Edema)
01/2016 - 08/2004
67Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage)
01/2016 - 02/2002
53Ischemia
10/2015 - 02/2002
51Anoxia (Hypoxia)
01/2016 - 09/2002
40Hemorrhage
01/2016 - 02/2002
39Stroke (Strokes)
01/2016 - 09/2003
38Brain Ischemia (Cerebral Ischemia)
08/2015 - 02/2002
30Inflammation
12/2015 - 07/2005
29Cerebral Hemorrhage
01/2016 - 10/2004
19Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
01/2016 - 07/2006
18Intracranial Vasospasm
12/2012 - 02/2002
11Wounds and Injuries (Trauma)
01/2016 - 01/2007
10Edema
01/2016 - 04/2005
10Body Weight (Weight, Body)
04/2013 - 03/2007
9Atrophy
09/2014 - 11/2009
8Hematoma
10/2015 - 05/2004
8Infarction
10/2014 - 07/2003
8Reperfusion Injury
01/2012 - 05/2004
7Hyperglycemia
01/2016 - 03/2007
6Hydrocephalus (Hydrocephaly)
01/2016 - 01/2011
4Hypotension (Low Blood Pressure)
01/2016 - 01/2005
4Intracranial Hemorrhages (Intracranial Hemorrhage)
01/2016 - 01/2008
4Spinal Cord Injuries (Spinal Cord Injury)
11/2015 - 01/2003
4Neoplasms (Cancer)
08/2013 - 01/2005
4Neurologic Manifestations (Neurological Manifestations)
05/2013 - 07/2003
4Hyperoxia
06/2012 - 09/2004
4Necrosis
07/2011 - 07/2002
4Muscle Spasticity (Spastic)
11/2010 - 07/2002
3Pulmonary Edema
01/2016 - 12/2009
3Carbon Monoxide Poisoning (Poisoning, Carbon Monoxide)
01/2014 - 03/2007
3Rupture
02/2013 - 01/2011
3Herpes Zoster
01/2011 - 12/2009
3Cerebral Palsy (Spastic Diplegia)
01/2011 - 01/2011
3Mental Retardation (Idiocy)
01/2011 - 01/2011

Drug/Important Bio-Agent (IBA)

55OxygenIBA
01/2016 - 02/2002
33salicylhydroxamic acid (SHAM)IBA
01/2016 - 09/2003
21HydrogenIBA
05/2013 - 08/2008
17Caspase 3 (Caspase-3)IBA
01/2016 - 07/2003
14Collagenases (Collagenase)FDA Link
06/2015 - 10/2004
12Granulocyte Colony-Stimulating Factor (G-CSF)IBA
10/2015 - 01/2007
10OsteopontinIBA
01/2016 - 02/2010
10Small Interfering RNA (siRNA)IBA
10/2015 - 03/2009
10Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2013 - 08/2004
9Evans Blue (Blue, Evans)FDA Link
01/2016 - 07/2006
9Glucose (Dextrose)FDA LinkGeneric
01/2016 - 03/2007
9Cyclooxygenase 2 (Cyclooxygenase-2)IBA
01/2016 - 02/2002
9Messenger RNA (mRNA)IBA
01/2012 - 02/2002
8IsofluraneFDA LinkGeneric
02/2014 - 07/2010
7CytokinesIBA
01/2016 - 11/2003
7ErythropoietinFDA Link
01/2015 - 02/2004
7Peroxidase (Myeloperoxidase)IBA
02/2014 - 06/2008
7Protein Kinases (Protein Kinase)IBA
12/2013 - 03/2002
7glucuronyl glucosamine glycan sulfate (Vessel)IBA
07/2012 - 09/2003
7Matrix Metalloproteinase 9 (Gelatinase B)IBA
01/2011 - 10/2004
6Reactive Oxygen Species (Oxygen Radicals)IBA
12/2015 - 05/2004
6ThrombinFDA Link
06/2015 - 04/2009
6MelatoninIBA
01/2011 - 01/2008
6NADPH Oxidase (NAD(P)H oxidase)IBA
08/2007 - 02/2004
5Phosphotransferases (Kinase)IBA
06/2015 - 08/2004
5N- (2- cyclohexyloxy- 4- nitrophenyl)methanesulfonamideIBA
06/2015 - 09/2009
5DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA
06/2015 - 07/2003
5Matrix MetalloproteinasesIBA
09/2013 - 07/2006
5HormonesIBA
01/2013 - 03/2007
5Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
02/2011 - 02/2002
4Hemoglobins (Hemoglobin)IBA
01/2016 - 02/2011
4InterleukinsIBA
05/2015 - 07/2009
4Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
02/2014 - 11/2003
4SphingosineIBA
02/2014 - 07/2010
4Proteins (Proteins, Gene)IBA
01/2014 - 09/2004
4fingolimod (FTY720)FDA Link
10/2013 - 02/2010
4Anesthetics (Anesthetic Agents)IBA
09/2012 - 03/2009
4Free RadicalsIBA
01/2011 - 04/2005
4Laminin (Merosin)IBA
01/2011 - 02/2010
3Sirolimus (Rapamycin)FDA Link
01/2016 - 07/2012
3Cannabinoid Receptors (Cannabinoid Receptor)IBA
01/2016 - 11/2014
3Glycoproteins (Glycoprotein)IBA
10/2014 - 02/2010
3P-SelectinIBA
02/2014 - 02/2004
3JNK Mitogen-Activated Protein KinasesIBA
02/2014 - 07/2005
32-methoxyestradiolIBA
09/2013 - 04/2008
3Vanadates (Orthovanadate)IBA
03/2012 - 01/2011
3SodiumIBA
03/2012 - 01/2011
3Minocycline (Cyclops)FDA LinkGeneric
12/2011 - 01/2011
3Arginine Vasopressin (Argipressin)IBA
03/2011 - 01/2011
3Brain-Derived Neurotrophic Factor (BDNF)IBA
02/2011 - 01/2008
3Oxyhemoglobins (Oxyhemoglobin)IBA
01/2011 - 07/2002
3Immunoglobulin G (IgG)IBA
11/2009 - 04/2008
3Adenosine Triphosphate (ATP)IBA
05/2009 - 07/2002
3Superoxide DismutaseIBA
03/2009 - 11/2004
3Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
04/2007 - 07/2002
2Insulin-Like Growth Factor I (IGF-1)IBA
01/2016 - 01/2005
2Blood Glucose (Blood Sugar)IBA
01/2016 - 01/2011
2Epidermal Growth Factor (EGF)IBA
10/2015 - 12/2014
2milk fat globuleIBA
10/2015 - 12/2014

Therapy/Procedure

27Ligation
01/2016 - 09/2002
16Hyperbaric Oxygenation
01/2015 - 09/2002
8Neurosurgical Procedures
01/2016 - 03/2007
8Electrocoagulation (Electrocautery)
07/2012 - 01/2007
5Sutures (Suture)
01/2016 - 07/2006
3Therapeutics
01/2016 - 06/2011