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Carlos A Zarate Selected Research

Ketamine

6/2015A single infusion of ketamine improves depression scores in patients with anxious bipolar depression.
5/2015Neural correlates of change in major depressive disorder anhedonia following open-label ketamine.
2/2015Rating depression over brief time intervals with the Hamilton Depression Rating Scale: standard vs. abbreviated scales.
1/2015Lithium and Valproate Levels Do Not Correlate with Ketamine's Antidepressant Efficacy in Treatment-Resistant Bipolar Depression.
1/2015Neural correlates of suicidal ideation and its reduction in depression.
1/2015Ketamine's antidepressant efficacy is extended for at least four weeks in subjects with a family history of an alcohol use disorder.
11/2014Improvement in suicidal ideation after ketamine infusion: relationship to reductions in depression and anxiety.
9/2014Effect of baseline anxious depression on initial and sustained antidepressant response to ketamine.
5/2014Clinical predictors of ketamine response in treatment-resistant major depression.
4/2014Do the dissociative side effects of ketamine mediate its antidepressant effects?
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Carlos A Zarate Research Topics

Disease

63Bipolar Disorder (Mania)
09/2015 - 01/2002
33Major Depressive Disorder (Major Depressive Disorders)
06/2015 - 01/2006
25Mood Disorders (Mood Disorder)
03/2015 - 01/2002
4Depressive Disorder (Melancholia)
01/2015 - 07/2004
4Substance-Related Disorders (Drug Abuse)
01/2014 - 08/2003
4Sleep Deprivation
06/2013 - 11/2002
4Weight Gain
11/2006 - 01/2002
2Alcoholism (Alcohol Abuse)
05/2014 - 12/2006
2Inflammation
05/2014 - 01/2010
2Post-Traumatic Stress Disorders (PTSD)
06/2013 - 03/2011
2Neurodegenerative Diseases (Neurodegenerative Disease)
01/2010 - 06/2009
2Anxiety Disorders (Anxiety Disorder)
09/2008 - 12/2006
2Nausea
07/2003 - 06/2002
1Temporal Lobe Epilepsy
04/2015
1Pervasive Child Development Disorders
05/2014
1Obsessive-Compulsive Disorder (Disorder, Obsessive-Compulsive)
05/2014
1Pancreatitis
05/2014
1Shock
01/2013
1B-Cell Lymphoma (Lymphoma, B Cell)
01/2010
1Nervous System Diseases (Neurological Disorders)
06/2009
1Psychotic Disorders (Schizoaffective Disorder)
06/2009
1Atrophy
06/2009
1Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
09/2008

Drug/Important Bio-Agent (IBA)

29KetamineFDA LinkGeneric
06/2015 - 12/2007
23LithiumIBA
06/2015 - 01/2002
16N-Methylaspartate (NMDA)IBA
01/2015 - 11/2003
13Valproic Acid (Valproate, Semisodium)FDA LinkGeneric
06/2015 - 01/2002
10Antidepressive Agents (Antidepressants)IBA
06/2015 - 11/2002
9Glutamic Acid (Glutamate)FDA Link
08/2014 - 11/2003
7olanzapine (Zyprexa)FDA Link
07/2010 - 01/2002
6Serotonin (5 Hydroxytryptamine)IBA
08/2014 - 11/2010
5Biological Markers (Surrogate Marker)IBA
06/2015 - 02/2009
5Scopolamine (Hyoscine)FDA Link
06/2015 - 03/2012
5RiluzoleFDA LinkGeneric
05/2014 - 04/2004
4Neurotransmitter Agents (Neurotransmitter)IBA
08/2014 - 01/2008
4Protein Kinase CIBA
01/2010 - 09/2007
3Sertraline (Zoloft)FDA LinkGeneric
01/2015 - 04/2014
3Dopamine (Intropin)FDA LinkGeneric
08/2014 - 11/2010
3Norepinephrine (Noradrenaline)FDA LinkGeneric
08/2014 - 11/2010
3CalciumIBA
02/2014 - 02/2011
3pramipexol (pramipexole)FDA LinkGeneric
07/2013 - 07/2004
3Dopamine Agonists (Dopamine Agonist)IBA
07/2013 - 11/2010
3Glycogen Synthase Kinase 3IBA
01/2010 - 01/2004
3TamoxifenFDA LinkGeneric
01/2009 - 09/2007
3lamotrigine (Lamictal)FDA LinkGeneric
04/2007 - 02/2004
2Carbon MonoxideIBA
06/2015 - 12/2006
2Glucose (Dextrose)FDA LinkGeneric
04/2015 - 03/2014
2salicylhydroxamic acid (SHAM)IBA
07/2014 - 04/2014
2EnzymesIBA
05/2014 - 03/2014
2GlucocorticoidsIBA
02/2014 - 11/2010
2RolipramIBA
01/2014 - 11/2012
25-HT1A Serotonin ReceptorIBA
10/2013 - 08/2013
2Brain-Derived Neurotrophic Factor (BDNF)IBA
03/2013 - 01/2010
2Excitatory Amino Acid AgentsIBA
02/2012 - 05/2008
2Adenosine Monophosphate (AMP)IBA
01/2010 - 06/2006
2alpha- Amino- 3- hydroxy- 5- methyl- 4- isoxazolepropionic Acid (AMPA)IBA
01/2009 - 11/2003
2Antipsychotic Agents (Antipsychotics)IBA
08/2008 - 12/2006
2Anticonvulsants (Antiepileptic Drugs)IBA
04/2007 - 12/2006
1OxygenIBA
06/2015
1Messenger RNA (mRNA)IBA
04/2015
1Flumazenil (Romazicon)FDA LinkGeneric
04/2015
1Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA
01/2015
1Nitric Oxide (Nitrogen Monoxide)FDA Link
08/2014
1Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
05/2014
1TransaminasesIBA
05/2014
1CytokinesIBA
02/2014
1Cocaine (Cocaine HCl)IBA
01/2014
1gamma-Aminobutyric Acid (GABA)IBA
10/2013
1Glutamate Receptors (Glutamate Receptor)IBA
10/2013
1Aminobutyric Acids (Aminobutyric Acid)IBA
10/2013
1norketamineIBA
08/2012
1ChromatinIBA
12/2011
1Transcription Factors (Transcription Factor)IBA
12/2011
1Histone Deacetylases (Histone Deacetylase)IBA
12/2011
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
08/2011
1GR 205171IBA
03/2011
1Neurokinin-1 Receptors (Neurokinin 1 Receptor)IBA
03/2011
1Inositol 1,4,5-TrisphosphateIBA
02/2011
1Adrenal Cortex Hormones (Corticosteroids)IBA
11/2010
1Tricyclic Antidepressive Agents (Tricyclic Antidepressants)IBA
11/2010
1Amphetamine (Amfetamine)FDA LinkGeneric
11/2010
1Uric Acid (Urate)IBA
08/2010
1quetiapine (Seroquel)FDA Link
07/2010
1Fluoxetine (Prozac)FDA LinkGeneric
08/2009
1Nerve Growth Factors (Neurotrophins)IBA
06/2009
1Proteins (Proteins, Gene)IBA
06/2009
1Amino Acid Transport System X-AG (Glutamate Transporter)IBA
01/2009
1Antimanic AgentsIBA
12/2008
1Purinergic AgentsIBA
08/2008
1Dipyridamole (Persantine)FDA LinkGeneric
08/2008
1Allopurinol (Remid)FDA LinkGeneric
08/2008
1Phosphotransferases (Kinase)IBA
09/2007
1Staphylococcal Protein A (A, Protein)IBA
09/2007
1AMPA Receptors (AMPA Receptor)IBA
04/2007

Therapy/Procedure

21Therapeutics
03/2015 - 01/2002
5Drug Therapy (Chemotherapy)
09/2015 - 06/2006
1Aftercare (After-Treatment)
10/2013
1Electrodes (Electrode)
01/2013
1Intravenous Infusions
10/2012
1Individualized Medicine
11/2010