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S Yoshino Selected Research

bucillamine (SA 96)

5/2006Treatment continuation rate in relation to efficacy and toxicity in long-term therapy with low-dose methotrexate, sulfasalazine, and bucillamine in 1,358 Japanese patients with rheumatoid arthritis.
1/2005The ability of disease modifying antirheumatic drugs to induce and maintain improvement in patients with rheumatoid arthritis. epidemiology of DMARDs treatment in Japan.
11/2000Effects of combinations of anti-rheumatic drugs on the production of vascular endothelial growth factor and basic fibroblast growth factor in cultured synoviocytes and patients with rheumatoid arthritis.

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S Yoshino Research Topics

Disease

20Rheumatoid Arthritis
05/2006 - 01/2000
9Neoplasms (Cancer)
12/2014 - 01/2000
8Osteoarthritis
04/2005 - 01/2000
5Arthritis (Polyarthritis)
11/2010 - 10/2000
5Inflammation
11/2010 - 04/2000
3Hyperplasia
10/2012 - 07/2005
3Experimental Arthritis
11/2007 - 04/2000
3Pulmonary Embolism
04/2005 - 12/2001
2Food Hypersensitivity (Food Allergy)
10/2012 - 01/2012
2Hypothermia
10/2012 - 01/2012
2Diarrhea
10/2012 - 01/2012
2Anaphylaxis (Anaphylactic Shock)
10/2012 - 01/2012
2Lung Injury
07/2008 - 07/2003
2Necrosis
08/2005 - 04/2000
2Venous Thrombosis (Deep-Vein Thrombosis)
04/2005 - 12/2001
2Esophageal Neoplasms (Esophageal Cancer)
03/2004 - 09/2000
2Stomach Neoplasms (Stomach Cancer)
12/2001 - 10/2000
2Pain (Aches)
09/2000 - 01/2000
1Asthma (Bronchial Asthma)
05/2013
1Hypersensitivity (Allergy)
01/2012
1Leukemia
01/2012
1Pneumonia (Pneumonitis)
01/2007
1Ulcer
06/2005
1Cicatrix (Scar)
06/2005
1Peptic Ulcer (Peptic Ulcers)
06/2005
1Suppuration
06/2005
1Thromboembolism
04/2005
1Acute Lung Injury
07/2003
1Systemic Lupus Erythematosus (Libman-Sacks Disease)
01/2003
1Fibrosis (Cirrhosis)
11/2002
1Protein S Deficiency (Deficiency, Protein S)
12/2001
1Synovitis
08/2001
1Wounds and Injuries (Trauma)
08/2001

Drug/Important Bio-Agent (IBA)

7AntigensIBA
05/2013 - 01/2005
4Interleukin-6 (Interleukin 6)IBA
07/2008 - 09/2000
4Methotrexate (Mexate)FDA LinkGeneric
05/2006 - 11/2000
3OvalbuminIBA
10/2012 - 03/2006
3Vehicle Emissions (Emissions, Vehicle)IBA
01/2007 - 07/2003
31-(2-(dodecyloxy)ethyl)pyrrolidine hydrochloride (DEP)IBA
01/2007 - 07/2003
3bucillamine (SA 96)IBA
05/2006 - 11/2000
3Immunoglobulin G (IgG)IBA
03/2006 - 03/2000
3CytokinesIBA
02/2006 - 04/2000
3Interferon-gamma (Interferon, gamma)IBA
08/2005 - 04/2000
3Messenger RNA (mRNA)IBA
12/2001 - 01/2000
2AntibodiesIBA
11/2010 - 01/2005
2Sulfasalazine (Azulfidine)FDA LinkGeneric
05/2006 - 02/2002
2Organic ChemicalsIBA
03/2006 - 07/2003
2Insulin-Like Growth Factor I (IGF-1)IBA
09/2005 - 11/2002
2RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
07/2005 - 01/2000
2Antirheumatic Agents (DMARD)IBA
01/2005 - 11/2000
2Gold Sodium Thiomalate (Sodium Aurothiomalate)IBA
01/2005 - 11/2000
2Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
09/2001 - 01/2000
2Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA
11/2000 - 10/2000
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
11/2000 - 10/2000
1Epidermal Growth Factor Receptor (EGF Receptor)IBA
12/2014
1Sirolimus (Rapamycin)FDA Link
10/2012
1tyrosine receptor (receptor, tyrosine)IBA
01/2012
1Immunoglobulins (Immunoglobulin)IBA
01/2012
1sunitinib (Sutent)FDA Link
01/2012
1Phosphotransferases (Kinase)IBA
01/2012
1Immunoglobulin E (IgE)IBA
01/2012
1Eosine Yellowish-(YS) (Eosin)IBA
11/2010
1Immunoglobulin Fab FragmentsIBA
11/2010
1Complement System Proteins (Complement)IBA
11/2010
1InterleukinsIBA
07/2008
1sinomenineIBA
11/2007
1CarbonIBA
10/2007
1ChemokinesIBA
01/2007
1CXC ChemokinesIBA
01/2007
1Chemotactic FactorsIBA
01/2007
1Interleukin-5 (Interleukin 5)IBA
03/2006
1Growth Hormone (Somatotropin)IBA
09/2005
1Substance PIBA
09/2005
1Interleukin-1beta (Interleukin 1 beta)IBA
08/2005
1enhanced green fluorescent proteinIBA
07/2005
1AngiostatinsIBA
07/2005
1Kanamycin KinaseIBA
07/2005
1Anti-Ulcer AgentsIBA
06/2005
1lansoprazole (Prevacid)FDA LinkGeneric
06/2005
1Famotidine (Pepcid)FDA LinkGeneric
06/2005
1Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
06/2005
1Leukocyte Elastase (Neutrophil Elastase)IBA
04/2005
1antithrombin III-protease complexIBA
04/2005
1fibrin fragment D (D-dimer)IBA
04/2005
1protein-arginine deiminaseIBA
01/2005
1AutoantibodiesIBA
01/2003
1Fibronectins (Fibronectin)IBA
11/2002
1Procollagen-Proline Dioxygenase (Prolyl Hydroxylase)IBA
09/2001
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
09/2001
1Stem Cell FactorIBA
09/2001
1Interleukin-12 (IL 12)IBA
08/2001
1Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA
08/2001
1HGF activatorIBA
08/2001

Therapy/Procedure

5Arthroplasty
04/2005 - 03/2001
2General Anesthesia
11/2004 - 03/2001
2Esophagectomy
03/2004 - 06/2000
1Oral Administration
08/2005
1Tourniquets
04/2005
1Mediastinoscopes
03/2004
1Distraction Osteogenesis
11/2002