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Merav Yogev-Falach Selected Research

rasagiline (Azilect)

1/2009Multifunctional neuroprotective derivatives of rasagiline as anti-Alzheimer's disease drugs.
10/2006A multifunctional, neuroprotective drug, ladostigil (TV3326), regulates holo-APP translation and processing.
1/2005Rasagiline: neurodegeneration, neuroprotection, and mitochondrial permeability transition.
6/2004Regulation of protein kinase C by the anti-Parkinson drug, MAO-B inhibitor, rasagiline and its derivatives, in vivo.
12/2003The importance of propargylamine moiety in the anti-Parkinson drug rasagiline and its derivatives in MAPK-dependent amyloid precursor protein processing.
5/2003Amyloid processing and signal transduction properties of antiparkinson-antialzheimer neuroprotective drugs rasagiline and TV3326.
10/2002Involvement of MAP kinase in the regulation of amyloid precursor protein processing by novel cholinesterase inhibitors derived from rasagiline.

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Merav Yogev-Falach Research Topics

Disease

5Alzheimer Disease (Alzheimer's Disease)
01/2009 - 10/2002
5Neuroblastoma
10/2006 - 10/2002
2Lewy Body Disease (Lewy Body Dementia)
01/2008 - 10/2006
2Parkinson Disease (Parkinson's Disease)
01/2005 - 12/2003
1Amyloid Plaque
09/2009
1Nervous System Diseases (Neurological Disorders)
09/2009
1Neoplasms (Cancer)
03/2009
1Dementia (Dementias)
01/2008
1Craniocerebral Trauma (Head Injury)
01/2005
1Anoxia (Hypoxia)
01/2005
1Ischemia
01/2005

Drug/Important Bio-Agent (IBA)

7rasagiline (Azilect)FDA Link
01/2009 - 10/2002
6Amyloid (Amyloid Fibrils)IBA
09/2009 - 10/2002
5Cholinesterases (Cholinesterase)IBA
01/2008 - 10/2002
5Monoamine Oxidase (MAO)IBA
01/2008 - 12/2003
5(N-propargyl-(3R) aminoindan-5-yl)-ethyl methyl carbamateIBA
01/2008 - 10/2002
3N-propargylIBA
06/2004 - 05/2003
3(N-propargyl-(3R) and (3S) aminoindan-5-yl)-ethyl methyl carbamateIBA
06/2004 - 10/2002
2methyl carbamateIBA
05/2003 - 10/2002
1N-(2-mercaptoethyl)dansylamideIBA
09/2009
1Congo RedIBA
09/2009
1ML 9IBA
03/2009
1Caspase 3 (Caspase-3)IBA
03/2009
1rivastigmine (Exelon)FDA LinkGeneric
10/2006
1Levodopa (L Dopa)FDA LinkGeneric
01/2005
1NeurotoxinsIBA
01/2005
1Phosphotransferases (Kinase)IBA
06/2004
1Staphylococcal Protein A (A, Protein)IBA
06/2004

Therapy/Procedure

1Drug Therapy (Chemotherapy)
03/2009