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D C Whitcomb Selected Research

Hereditary pancreatitis

5/2006A 93 year old man with the PRSS1 R122H mutation, low SPINK1 expression, and no pancreatitis: insights into phenotypic non-penetrance.
8/2001Lessons from hereditary pancreatitis.
7/2001Cigarette smoking as a risk factor for pancreatic cancer in patients with hereditary pancreatitis.
1/2001SPINK1 mutations are associated with multiple phenotypes.
1/2001Hereditary pancreatitis: a model for understanding the genetic basis of acute and chronic pancreatitis.
5/2000Risk factors for cancer in hereditary pancreatitis. International Hereditary Pancreatitis Study Group.

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D C Whitcomb Research Topics

Disease

8Chronic Pancreatitis
05/2011 - 09/2000
8Pancreatitis
06/2010 - 05/2000
3Inflammation
06/2010 - 05/2006
2Obesity
11/2005 - 07/2004
2Pancreatic Neoplasms (Pancreatic Cancer)
07/2001 - 05/2000
2Wounds and Injuries (Trauma)
11/2000 - 03/2000
1Necrosis
01/2013
1Weight Loss (Weight Reduction)
05/2011
1Exocrine Pancreatic Insufficiency
05/2011
1Weight Gain
05/2011
1Fibrosis (Cirrhosis)
07/2007
1Body Weight (Weight, Body)
07/2004
1Autolysis
02/2002
1Pancreatic Diseases (Pancreatic Disease)
01/2001
1Neoplasms (Cancer)
05/2000
1Cicatrix (Scar)
03/2000

Drug/Important Bio-Agent (IBA)

6Hereditary pancreatitisIBA
05/2006 - 05/2000
4TrypsinIBA
08/2001 - 09/2000
3Serine Proteases (Serine Protease)IBA
06/2005 - 01/2001
2Interleukin-6 (Interleukin 6)IBA
06/2010 - 09/2000
2Messenger RNA (mRNA)IBA
05/2006 - 11/2000
2Complementary DNA (cDNA)IBA
11/2000 - 03/2000
1Caspase 1 (ICE Protease)IBA
01/2013
1HMGB1 Protein (HMG1)IBA
01/2013
1Pancrelipase (Creon)FDA Link
05/2011
1Octreotide (Sandostatin)FDA LinkGeneric
01/2011
1AntioxidantsIBA
01/2011
1VitaminsIBA
01/2011
1AdipokinesIBA
06/2010
1LeptinIBA
06/2010
1ResistinIBA
06/2010
1AdiponectinIBA
06/2010
1Nicotinamide PhosphoribosyltransferaseIBA
06/2010
1Biological Markers (Surrogate Marker)IBA
07/2007
1TrypsinogenIBA
05/2006
1Acute-Phase Proteins (Acute-Phase Protein)IBA
05/2006
1Neuropeptide YIBA
11/2005
1Peptide YYIBA
11/2005
1HormonesIBA
07/2004
1Arginine (L-Arginine)FDA Link
02/2002
1EP4 Subtype Prostaglandin E ReceptorsIBA
11/2000
1C-Reactive ProteinIBA
09/2000
1GelsIBA
03/2000
1Chaperonin Containing TCP-1IBA
03/2000
1CosmeticsIBA
03/2000
1DNA (Deoxyribonucleic Acid)IBA
03/2000

Therapy/Procedure

2Enzyme Replacement Therapy
05/2011 - 01/2011
1Role Playing (Playing, Role)
08/2001