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Sean P J Whelan Selected Research

Vesicular Stomatitis

12/2015Tracking the Fate of Genetically Distinct Vesicular Stomatitis Virus Matrix Proteins Highlights the Role for Late Domains in Assembly.
1/2015Recoding of the vesicular stomatitis virus L gene by computer-aided design provides a live, attenuated vaccine candidate.
8/2014A genome-wide small interfering RNA screen identifies host factors required for vesicular stomatitis virus infection.
4/2014Sensitivity of the polymerase of vesicular stomatitis virus to 2' substitutions in the template and nucleotide triphosphate during initiation and elongation.
3/2014mRNA cap methylation influences pathogenesis of vesicular stomatitis virus in vivo.
11/2013Uptake of rabies virus into epithelial cells by clathrin-mediated endocytosis depends upon actin.
8/2012Structural properties of the C terminus of vesicular stomatitis virus N protein dictate N-RNA complex assembly, encapsidation, and RNA synthesis.
7/2012Architecture and regulation of negative-strand viral enzymatic machinery.
3/2012Mechanism of RNA synthesis initiation by the vesicular stomatitis virus polymerase.
1/2012Genetic inactivation of COPI coatomer separately inhibits vesicular stomatitis virus entry and gene expression.
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Sean P J Whelan Research Topics

Disease

22Vesicular Stomatitis
12/2015 - 09/2002
7Infection
08/2014 - 01/2010
1Contagious Ecthyma (Orf)
01/2015

Drug/Important Bio-Agent (IBA)

12RNA (Ribonucleic Acid)IBA
04/2014 - 11/2005
8Messenger RNA (mRNA)IBA
03/2014 - 11/2005
4Glycoproteins (Glycoprotein)IBA
12/2015 - 10/2010
3Nucleocapsid ProteinsIBA
09/2012 - 11/2010
2Proteins (Proteins, Gene)IBA
12/2015 - 07/2012
2RNA Replicase (RNA Dependent RNA Polymerase)IBA
06/2011 - 09/2002
2ClathrinIBA
01/2010 - 04/2009
1RibonucleoproteinsIBA
12/2015
1Codon (Codons)IBA
01/2015
1Small Interfering RNA (siRNA)IBA
08/2014
1triphosphoric acid (triphosphate)IBA
04/2014
1S-Adenosylmethionine (Ademetionine)IBA
03/2014
1Dynamins (Dynamin)IBA
11/2013
1NucleoproteinsIBA
08/2012
1NucleotidesIBA
03/2012
1Coat Protein Complex I (COPI)IBA
01/2012
1Membrane Glycoproteins (Membrane Glycoprotein)IBA
08/2011
1Viral RNAIBA
01/2010
1Ribose (D-Ribose)IBA
11/2009
1Methionine (L-Methionine)FDA Link
11/2009
1sinefunginIBA
04/2007