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David Weinshenker Selected Research

Disulfiram (Antabuse)

7/2014Effects of pharmacologic dopamine β-hydroxylase inhibition on cocaine-induced reinstatement and dopamine neurochemistry in squirrel monkeys.
1/2012Chronic inhibition of dopamine β-hydroxylase facilitates behavioral responses to cocaine in mice.
11/2010Disulfiram attenuates drug-primed reinstatement of cocaine seeking via inhibition of dopamine β-hydroxylase.
8/2009mechanisms of disulfiram-induced cocaine abstinence: antabuse and cocaine relapse.
6/2008Effects of disulfiram and dopamine beta-hydroxylase knockout on cocaine-induced seizures.
7/2007There and back again: a tale of norepinephrine and drug addiction.
10/2006Dopamine beta-hydroxylase knockout mice have alterations in dopamine signaling and are hypersensitive to cocaine.

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David Weinshenker Research Topics

Disease

11Seizures (Seizure)
10/2013 - 06/2002
9Epilepsy (Aura)
10/2013 - 06/2002
8Cocaine-Related Disorders (Cocaine Addiction)
07/2014 - 10/2006
4Alzheimer Disease (Alzheimer's Disease)
01/2015 - 01/2013
3Schizophrenia (Dementia Praecox)
10/2015 - 03/2005
3Substance-Related Disorders (Drug Abuse)
04/2015 - 10/2006
2Memory Disorders (Memory Loss)
02/2014 - 01/2013
2Alcoholism (Alcohol Abuse)
01/2012 - 08/2009
2Psychotic Disorders (Schizoaffective Disorder)
09/2006 - 03/2005
1Dystonia (Limb Dystonia)
10/2015
1Dyskinesias (Dyskinesia)
10/2015
1Dystonic Disorders (Writer's Cramp)
10/2015
1Menkes Kinky Hair Syndrome (Menkes Disease)
10/2015
1Generalized Epilepsy
07/2013
1Genetic Predisposition to Disease (Genetic Predisposition)
07/2013
1Febrile Seizures (Febrile Seizure)
07/2013
1Status Epilepticus (Complex Partial Status Epilepticus)
12/2012
1Lesch-Nyhan Syndrome (Choreoathetosis Self Mutilation Hyperuricemia Syndrome)
01/2011
1Nervous System Diseases (Neurological Disorders)
01/2011
1Sleep Disorders
03/2010
1Sleep Initiation and Maintenance Disorders (Insomnia)
03/2010
1Infection
03/2010
1Neurodegenerative Diseases (Neurodegenerative Disease)
06/2009
1Parkinson Disease (Parkinson's Disease)
06/2009
1Tremor (Tremors)
06/2009
1Olfaction Disorders (Anosmia)
06/2009
1Hypokinesia (Bradykinesia)
06/2009
1Hypothermia
05/2009
1Tachycardia (Tachyarrhythmias)
02/2007
1Hypersensitivity (Allergy)
10/2006
1Brain Injuries (Brain Injury)
09/2006
1Birth Injuries (Birth Injury)
09/2006
1Bipolar Disorder (Mania)
06/2005
1Mood Disorders (Mood Disorder)
06/2005
1Bradycardia
01/2004

Drug/Important Bio-Agent (IBA)

10Norepinephrine (Noradrenaline)FDA LinkGeneric
01/2015 - 01/2002
9Dopamine beta-HydroxylaseIBA
03/2010 - 01/2002
8Dopamine (Intropin)FDA LinkGeneric
10/2015 - 01/2002
7Cocaine (Cocaine HCl)IBA
04/2015 - 10/2006
7Disulfiram (Antabuse)FDA Link
07/2014 - 10/2006
4Flurothyl (Flurotyl)IBA
07/2013 - 06/2005
3Antidepressive Agents (Antidepressants)IBA
01/2013 - 04/2006
2Amyloid (Amyloid Fibrils)IBA
06/2014 - 01/2013
2Pilocarpine (Ocusert)FDA LinkGeneric
10/2013 - 12/2012
2GalaninIBA
10/2013 - 06/2005
2Morphine (MS Contin)FDA LinkGeneric
07/2007 - 01/2002
2Tyrosine 3-Monooxygenase (Tyrosine Hydroxylase)IBA
09/2006 - 03/2005
2Catechol O-Methyltransferase (Methyltransferase, Catechol)IBA
09/2006 - 03/2005
2Norepinephrine Plasma Membrane Transport Proteins (Norepinephrine Transporter)IBA
04/2006 - 03/2006
1CopperIBA
10/2015
1Dopamine Agonists (Dopamine Agonist)IBA
10/2015
1MicronutrientsIBA
10/2015
1Levodopa (L Dopa)FDA LinkGeneric
10/2015
1Trihexyphenidyl (Artane)FDA LinkGeneric
10/2015
1Dopamine AntagonistsIBA
10/2015
1Presenilin-1IBA
06/2014
16,7-dihydroxyflavoneIBA
02/2014
1gamma-Aminobutyric Acid (GABA)IBA
07/2013
1Ion Channels (Ion Channel)IBA
07/2013
1Sodium Channels (Sodium Channel)IBA
07/2013
1Glutamic Acid (Glutamate)FDA Link
07/2013
1nepicastatIBA
05/2013
1Anticonvulsants (Antiepileptic Drugs)IBA
01/2013
1Carbon MonoxideIBA
12/2012
1Hypoxanthine Phosphoribosyltransferase (Hypoxanthine Guanine Phosphoribosyltransferase)IBA
01/2011
1lambda Spi-1IBA
03/2010
1Aldehyde DehydrogenaseIBA
08/2009
1Kainic Acid (Kainate)IBA
05/2007
1HormonesIBA
02/2007
1Serotonin ReceptorsIBA
10/2006
1Dopamine D4 Receptors (Dopamine D4 Receptor)IBA
09/2006
1GTP-Binding Proteins (G-Protein)IBA
09/2006
1Phosphotransferases (Kinase)IBA
09/2006
1Street Drugs (Illicit Drugs)IBA
09/2006
1Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA
09/2006
1reboxetine (Vestra)IBA
04/2006
1venlafaxine (Effexor)FDA LinkGeneric
04/2006
1Bupropion (Wellbutrin)FDA LinkGeneric
04/2006
1Imipramine (Janimine)FDA LinkGeneric
04/2006
1Pentylenetetrazole (Metrazol)IBA
04/2006
1Desipramine (Pertofrane)FDA LinkGeneric
04/2006
1Sertraline (Zoloft)FDA LinkGeneric
04/2006
1ConvulsantsIBA
03/2006
1NeuropeptidesIBA
06/2005
1Valproic Acid (Valproate, Semisodium)FDA LinkGeneric
06/2005
1G-protein-coupled receptor kinase 6IBA
03/2005
1Phencyclidine (Angel Dust)IBA
03/2005
1Ethanol (Ethyl Alcohol)IBA
03/2005
1Amphetamine (Amfetamine)FDA LinkGeneric
03/2005
1Antipsychotic Agents (Antipsychotics)IBA
03/2005

Therapy/Procedure

6Drug Therapy (Chemotherapy)
07/2014 - 10/2006
2Analgesia
05/2009 - 01/2002
2Ketogenic Diet
11/2008 - 03/2006
1Oral Administration
02/2014
1Induced Hyperthermia (Thermotherapy)
07/2013
1Therapeutics
12/2012
1Sympathectomy (Sympathectomies)
06/2009
1Protein-Restricted Diet (Diet, Protein Restricted)
11/2008
1Cesarean Section (Caesarean Section)
03/2005
1Caloric Restriction
01/2004