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Weiguang Wang Selected Research

Disulfiram (Antabuse)

10/2015Hot melt extruded and injection moulded disulfiram-loaded PLGA millirods for the treatment of glioblastoma multiforme via stereotactic injection.
3/2015Development of disulfiram-loaded poly(lactic-co-glycolic acid) wafers for the localised treatment of glioblastoma multiforme: a comparison of manufacturing techniques.
2/2015Disulfiram-loaded immediate and extended release vaginal tablets for the localised treatment of cervical cancer.
11/2014Development of disulfiram-loaded vaginal rings for the localised treatment of cervical cancer.
9/2014Liposome encapsulated Disulfiram inhibits NFκB pathway and targets breast cancer stem cells in vitro and in vivo.
1/2014Disulfiram targeting lymphoid malignant cell lines via ROS-JNK activation as well as Nrf2 and NF-kB pathway inhibition.
12/2011Disulfiram/copper complex activated JNK/c-jun pathway and sensitized cytotoxicity of doxorubicin in doxorubicin resistant leukemia HL60 cells.
4/2010Disulfiram/copper complex inhibiting NFkappaB activity and potentiating cytotoxic effect of gemcitabine on colon and breast cancer cell lines.
4/2003Disulfiram-mediated inhibition of NF-kappaB activity enhances cytotoxicity of 5-fluorouracil in human colorectal cancer cell lines.

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Weiguang Wang Research Topics

Disease

10Neoplasms (Cancer)
02/2015 - 04/2003
5Breast Neoplasms (Breast Cancer)
10/2014 - 08/2007
4Thrombocytopenia (Thrombopenia)
03/2015 - 01/2012
4Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2015 - 12/2011
4Colorectal Neoplasms (Colorectal Cancer)
05/2010 - 11/2002
3Glioblastoma (Glioblastoma Multiforme)
10/2015 - 04/2013
3Alcoholism (Alcohol Abuse)
01/2014 - 04/2003
2Paraproteinemias (Monoclonal Gammopathy)
03/2014 - 02/2014
1Postmenopausal Osteoporosis
12/2014
1Lung Neoplasms (Lung Cancer)
11/2014
1Pathologic Neovascularization
10/2014
1B-Cell Lymphoma (Lymphoma, B Cell)
03/2014
1Membranoproliferative Glomerulonephritis (Membranoproliferative Glomerulonephritis, Type II)
02/2014
1Chronic Kidney Failure (Chronic Renal Failure)
12/2013
1Blindness (Hysterical Blindness)
12/2013
1Myeloid Leukemia (Leukemia, Myelocytic)
08/2013
1Autoimmune Diseases (Autoimmune Disease)
08/2013
1Osteopetrosis
07/2012
1Leukemia
12/2011
1Spontaneous Fractures (Pathological Fracture)
01/2011
1Pycnodysostosis
01/2011
1Adenocarcinoma
01/2009

Drug/Important Bio-Agent (IBA)

9Disulfiram (Antabuse)FDA Link
10/2015 - 04/2003
7Fluorouracil (Carac)FDA LinkGeneric
05/2010 - 11/2002
4Inosine Triphosphate (ITP)IBA
03/2015 - 01/2012
3CalcineurinIBA
10/2014 - 08/2007
3CopperIBA
01/2014 - 04/2010
3NF-kappa B (NF-kB)IBA
05/2010 - 04/2003
2polylactic acid-polyglycolic acid copolymer (PLGA)IBA
10/2015 - 03/2015
2Plasma Membrane Calcium-Transporting ATPasesIBA
10/2014 - 12/2012
2Dexamethasone (Maxidex)FDA LinkGeneric
07/2014 - 08/2013
2Immunoglobulin A (IgA)IBA
03/2014 - 02/2014
2triptolideIBA
08/2013 - 05/2010
2CalciumIBA
12/2012 - 08/2007
2DNA (Deoxyribonucleic Acid)IBA
01/2008 - 11/2004
1Interleukin-10 (Interleukin 10)IBA
03/2015
1Vaginal Creams, Foams, and Jellies (Vaginal Tablet)IBA
02/2015
1TabletsIBA
02/2015
1Histone Deacetylase InhibitorsIBA
01/2015
1N- (2- amino- 5- fluorobenzyl)- 4- (N- (pyridine- 3- acrylyl)aminomethyl)benzamideIBA
01/2015
1fludarabineIBA
12/2014
1Cytarabine (Cytosar-U)FDA LinkGeneric
12/2014
1Estrogens (Estrogen)FDA Link
12/2014
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
10/2014
1glucuronyl glucosamine glycan sulfate (Vessel)IBA
10/2014
1Liposomes (Liposome)IBA
09/2014
1familial juvenile NephronophthisisIBA
12/2013
1Interleukin-23 (Interleukin 23)IBA
08/2013
1temozolomide (Temodar)FDA LinkGeneric
04/2013
1Paclitaxel (Taxol)FDA LinkGeneric
12/2012
1Fas Ligand Protein (Fas Ligand)IBA
12/2012
1beta-apocarotenoid-14',13'-dioxygenase (ADO)IBA
07/2012
1Small Interfering RNA (siRNA)IBA
01/2012
1Doxorubicin (Adriamycin)FDA LinkGeneric
12/2011
1Cathepsin KIBA
01/2011
1Reactive Oxygen Species (Oxygen Radicals)IBA
05/2010
1gemcitabineFDA Link
04/2010
1Messenger RNA (mRNA)IBA
01/2009
1capecitabine (Xeloda)FDA Link
01/2009
1Propidium (Propidium Iodide)IBA
01/2008
1NucleotidesIBA
01/2008
1Bromodeoxyuridine (BrdU)IBA
01/2008
1Adenosine Triphosphatases (ATPase)IBA
08/2007
1UridineIBA
05/2007
1cerivastatin (Kazak)FDA Link
11/2002

Therapy/Procedure

4Drug Therapy (Chemotherapy)
04/2013 - 04/2003
2Therapeutics
09/2014 - 01/2009
1Female Contraceptive Devices (Vaginal Ring)
11/2014
1Sutures (Suture)
01/2011
1Radiotherapy
01/2009