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Norbert F Voelkel Selected Research

Idiopathic pulmonary hypertension

3/2015The need to recognize the pulmonary circulation and the right ventricle as an integrated functional unit: facts and hypotheses (2013 Grover Conference series).
1/2015Increased eicosanoid levels in the Sugen/chronic hypoxia model of severe pulmonary hypertension.
9/2014Treatment for pulmonary arterial hypertension-associated right ventricular dysfunction.
7/2014SuHx rat model: partly reversible pulmonary hypertension and progressive intima obstruction.
6/2014Histone deacetylase inhibition with trichostatin A does not reverse severe angioproliferative pulmonary hypertension in rats (2013 Grover Conference series).
1/2014IL-32 promotes angiogenesis.
8/2013Blocking macrophage leukotriene b4 prevents endothelial injury and reverses pulmonary hypertension.
5/2013Antioxidants for the treatment of patients with severe angioproliferative pulmonary hypertension?
1/2013Thyroid hormone is highly permissive in angioproliferative pulmonary hypertension in rats.
1/2013Metabolic gene remodeling and mitochondrial dysfunction in failing right ventricular hypertrophy secondary to pulmonary arterial hypertension.
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Norbert F Voelkel Research Topics

Disease

36Pulmonary Hypertension (Ayerza Syndrome)
12/2015 - 04/2002
30Anoxia (Hypoxia)
11/2015 - 04/2002
24Emphysema
08/2014 - 05/2002
14Inflammation
12/2015 - 10/2004
12Chronic Obstructive Pulmonary Disease (COPD)
09/2014 - 06/2003
7Heart Failure
03/2015 - 05/2002
6Infection
09/2014 - 09/2003
6Neoplasms (Cancer)
06/2014 - 12/2005
6Hypertrophy
08/2013 - 04/2002
6Acute Lung Injury
07/2012 - 05/2003
5Fibrosis (Cirrhosis)
02/2015 - 12/2007
4Vascular Diseases (Vascular Disease)
03/2015 - 08/2005
4Right Ventricular Hypertrophy
06/2014 - 08/2005
4Lung Injury
02/2012 - 03/2006
3Sepsis (Septicemia)
09/2014 - 06/2011
3Connective Tissue Diseases (Connective Tissue Disease)
08/2013 - 06/2009
3Thrombosis (Thrombus)
07/2011 - 06/2004
3Lung Diseases (Lung Disease)
08/2006 - 05/2002
2Right Ventricular Dysfunction
09/2014 - 05/2011
2Cardiomegaly (Heart Hypertrophy)
06/2014 - 06/2013
2Thyroid Diseases (Thyroid Disease)
01/2013 - 09/2009
2Hypothyroidism
01/2013 - 04/2012
2Rare Diseases (Rare Disease)
12/2012 - 06/2004
2Systolic Heart Failure
01/2012 - 09/2010
2Hypertension (High Blood Pressure)
02/2011 - 05/2006
2Obesity
09/2009 - 05/2006
2HIV Infections (HIV Infection)
09/2008 - 08/2006
2Ischemia
12/2007 - 01/2007
1Chronic Disease (Chronic Diseases)
03/2015
1Multiple Organ Failure (MODS)
09/2014
1Hemorrhage
08/2014
1Glioblastoma (Glioblastoma Multiforme)
01/2014

Drug/Important Bio-Agent (IBA)

29Idiopathic pulmonary hypertensionIBA
03/2015 - 05/2002
21Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
03/2015 - 05/2002
19Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
03/2015 - 05/2002
14SU 5416 (SU5416)IBA
02/2015 - 04/2002
10SmokeIBA
08/2014 - 03/2005
5MonocrotalineIBA
11/2015 - 12/2010
5glucuronyl glucosamine glycan sulfate (Vessel)IBA
09/2014 - 06/2004
5Proteins (Proteins, Gene)IBA
06/2013 - 12/2004
4Messenger RNA (mRNA)IBA
02/2015 - 05/2002
4AntibodiesIBA
05/2012 - 04/2005
4Epoprostenol (Prostacyclin)FDA LinkGeneric
04/2009 - 12/2005
3Leukotriene B4IBA
12/2015 - 05/2003
3Phosphotransferases (Kinase)IBA
03/2015 - 05/2002
3CollagenIBA
02/2015 - 03/2006
3OxygenIBA
09/2014 - 01/2009
3Ascorbic Acid (Vitamin C)FDA LinkGeneric
09/2014 - 06/2011
3Peroxidase (Myeloperoxidase)IBA
08/2014 - 01/2007
3Histone Deacetylases (Histone Deacetylase)IBA
06/2014 - 03/2011
3Heme Oxygenase-1IBA
05/2013 - 04/2004
3Caspase 3 (Caspase-3)IBA
02/2012 - 04/2004
3Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
07/2011 - 07/2007
3prostacyclin synthetase (prostacyclin synthase)IBA
04/2007 - 12/2005
2Adrenergic Receptors (Adrenergic Receptor)IBA
09/2014 - 09/2010
2trichostatin A (A 300)IBA
06/2014 - 03/2011
2Interleukin-1 (Interleukin 1)IBA
04/2014 - 01/2012
2carvedilol (Coreg)FDA LinkGeneric
06/2013 - 09/2010
2ProtandimIBA
05/2013 - 11/2009
2EnzymesIBA
05/2013 - 12/2011
2AntioxidantsIBA
05/2013 - 02/2011
2Thyroid HormonesIBA
01/2013 - 04/2012
2Estrogens (Estrogen)FDA Link
01/2013 - 09/2009
2OvalbuminIBA
11/2012 - 10/2012
2MicroRNAs (MicroRNA)IBA
09/2012 - 03/2011
2Dehydroascorbic AcidIBA
07/2012 - 06/2011
2CopperIBA
05/2012 - 01/2012
2Bone Morphogenetic Proteins (Bone Morphogenetic Protein)IBA
09/2011 - 12/2004
2CyclinsIBA
01/2009 - 09/2003
2ResistinIBA
01/2009 - 02/2008
2DNA (Deoxyribonucleic Acid)IBA
01/2009 - 09/2003
2Viral ProteinsIBA
09/2008 - 08/2006
2CytokinesIBA
07/2007 - 01/2007
2Biological Markers (Surrogate Marker)IBA
01/2007 - 03/2005
2T-Cell Antigen Receptors (T-Cell Receptor)IBA
11/2006 - 09/2005
2Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA
10/2006 - 03/2003
2benzyloxycarbonyl-asparagine (Z-Asp)IBA
03/2006 - 04/2002
2BradykininIBA
08/2005 - 04/2002
1Reactive Oxygen Species (Oxygen Radicals)IBA
12/2015
1Serotonin Plasma Membrane Transport Proteins (Serotonin Transporter)IBA
11/2015
1Serotonin (5 Hydroxytryptamine)IBA
11/2015
1Vascular Endothelial Growth Factor Receptor-3 (Flt 4)IBA
03/2015
1ProcollagenIBA
02/2015
1Iloprost (Ventavis)FDA Link
02/2015
1Connective Tissue Growth FactorIBA
02/2015
1Diethylcarbamazine (Hetrazan)FDA Link
01/2015
1Arachidonate 5-Lipoxygenase (5 Lipoxygenase)IBA
01/2015
1Cyclooxygenase 2 (Cyclooxygenase-2)IBA
01/2015
1Glutathione (Reduced Glutathione)IBA
08/2014
1caffeic acidIBA
08/2014
1Phenobarbital (Luminal)FDA Link
08/2014
1Pancreatic Elastase (Elastase)IBA
08/2014
1Histone Deacetylase InhibitorsIBA
06/2014
1CXCR ReceptorsIBA
01/2014
1JM 3100FDA Link
01/2014
1CXCR4 Receptors (CXCR4 Receptor)IBA
01/2014
1von Willebrand FactorIBA
01/2014

Therapy/Procedure

3Subcutaneous Injections
08/2014 - 03/2007
2Transplants (Transplant)
12/2007 - 05/2006
1Parenteral Infusions
09/2014