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Eric Van Cutsem Selected Research

panitumumab (Vectibix)

12/2015Analysis of KRAS/NRAS Mutations in a Phase III Study of Panitumumab with FOLFIRI Compared with FOLFIRI Alone as Second-line Treatment for Metastatic Colorectal Cancer.
6/2015Safety and Activity of the First-in-Class Sym004 Anti-EGFR Antibody Mixture in Patients with Refractory Colorectal Cancer.
8/2014Randomized phase Ib/II trial of rilotumumab or ganitumab with panitumumab versus panitumumab alone in patients with wild-type KRAS metastatic colorectal cancer.
6/2013An analysis of the treatment effect of panitumumab on overall survival from a phase 3, randomized, controlled, multicenter trial (20020408) in patients with chemotherapy refractory metastatic colorectal cancer.
4/2013Massively parallel tumor multigene sequencing to evaluate response to panitumumab in a randomized phase III study of metastatic colorectal cancer.
2/2013Mutant KRAS codon 12 and 13 alleles in patients with metastatic colorectal cancer: assessment as prognostic and predictive biomarkers of response to panitumumab.
11/2010Randomized phase III study of panitumumab with fluorouracil, leucovorin, and irinotecan (FOLFIRI) compared with FOLFIRI alone as second-line treatment in patients with metastatic colorectal cancer.
8/2010Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis.
4/2009Association of progression-free survival, overall survival, and patient-reported outcomes by skin toxicity and KRAS status in patients receiving panitumumab monotherapy.
1/2009Acute and long-term gastrointestinal consequences of chemotherapy.
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Eric Van Cutsem Research Topics

Disease

75Colorectal Neoplasms (Colorectal Cancer)
12/2015 - 04/2002
58Neoplasms (Cancer)
11/2015 - 07/2004
20Colonic Neoplasms (Colon Cancer)
11/2015 - 04/2002
19Stomach Neoplasms (Stomach Cancer)
07/2015 - 01/2002
19Disease Progression
05/2015 - 01/2004
15Neutropenia
05/2015 - 01/2004
14Adenocarcinoma
10/2014 - 08/2005
12Neoplasm Metastasis (Metastasis)
11/2015 - 01/2007
9Pancreatic Neoplasms (Pancreatic Cancer)
10/2013 - 03/2004
8Neuroendocrine Tumors (Neuroendocrine Tumor)
12/2015 - 01/2010
8Hypertension (High Blood Pressure)
06/2015 - 09/2009
8Fatigue
05/2015 - 02/2011
7Diarrhea
02/2015 - 01/2007
6Stomatitis
02/2015 - 01/2004
6Exanthema (Rash)
02/2015 - 10/2007
6Carcinoma (Carcinomatosis)
12/2012 - 12/2004
5Carcinoid Tumor (Carcinoid)
12/2015 - 01/2004
5Rectal Neoplasms (Rectal Cancer)
01/2014 - 02/2005
4Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
04/2013 - 01/2005
3Thrombocytopenia (Thrombopenia)
06/2015 - 04/2013
3Abdominal Pain (Pain, Abdominal)
10/2014 - 03/2011
3Anemia
04/2013 - 02/2011
3Microsatellite Instability
11/2012 - 09/2009
3Nausea
02/2011 - 01/2004
3Vomiting
02/2011 - 01/2007
3Gastrointestinal Neoplasms (Gastrointestinal Cancer)
09/2008 - 12/2005
2Proteinuria
06/2015 - 01/2013
2Acne Vulgaris
07/2014 - 08/2005
2Peripheral Nervous System Diseases (PNS Diseases)
10/2013 - 05/2013
2Hemorrhage
01/2013 - 05/2011
2Asthenia
01/2013 - 02/2011
2Thromboembolism
01/2013 - 05/2011
2Renal Cell Carcinoma (Grawitz Tumor)
07/2012 - 01/2005
2Pain (Aches)
11/2009 - 08/2007
2Cachexia
01/2008 - 01/2005
2Eczema
10/2007 - 08/2005
2Acneiform Eruptions
10/2007 - 08/2005
2Alopecia (Baldness)
01/2007 - 01/2004
1Leukopenia
05/2015
1Primitive Neuroectodermal Tumors (PNET)
03/2015
1Deglutition Disorders (Dysphagia)
02/2015

Drug/Important Bio-Agent (IBA)

39Fluorouracil (Carac)FDA LinkGeneric
12/2015 - 04/2002
32Epidermal Growth Factor Receptor (EGF Receptor)IBA
07/2015 - 07/2004
26Leucovorin (Folinic Acid)FDA Link
12/2015 - 04/2002
25cetuximab (Erbitux)FDA Link
06/2015 - 07/2004
24irinotecan (Camptosar)FDA LinkGeneric
12/2015 - 04/2002
24oxaliplatin (Eloxatin)FDA LinkGeneric
11/2015 - 04/2002
21bevacizumabFDA Link
05/2015 - 12/2004
14panitumumab (Vectibix)FDA Link
12/2015 - 01/2007
14capecitabine (Xeloda)FDA Link
11/2015 - 04/2002
13Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2015 - 01/2007
10gemcitabineFDA Link
10/2013 - 03/2004
9Cisplatin (Platino)FDA LinkGeneric
07/2014 - 08/2005
7Biological Markers (Surrogate Marker)IBA
08/2015 - 01/2004
7DNA (Deoxyribonucleic Acid)IBA
08/2015 - 04/2008
7docetaxel (Taxotere)FDA Link
01/2008 - 01/2004
6XELOXIBA
11/2015 - 06/2004
6afliberceptIBA
09/2015 - 10/2012
6everolimusFDA Link
03/2015 - 01/2010
5ParaffinIBA
04/2014 - 01/2007
5Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
10/2012 - 08/2005
4Octreotide (Sandostatin)FDA LinkGeneric
12/2015 - 04/2010
4erlotinib (CP 358,774)FDA Link
07/2012 - 08/2005
4AntibodiesIBA
12/2010 - 05/2007
4thymidine 5'-triphosphate (TTP)IBA
08/2010 - 06/2004
3Angiogenesis InhibitorsIBA
09/2015 - 01/2011
3trastuzumab (Herceptin)FDA Link
07/2015 - 08/2010
3Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
05/2015 - 03/2011
3Codon (Codons)IBA
03/2015 - 10/2010
3Sodium Glutamate (Accent)IBA
10/2013 - 07/2013
3CytotoxinsIBA
06/2010 - 01/2004
3Formaldehyde (Formol)FDA Link
10/2009 - 01/2007
3Monoclonal AntibodiesIBA
05/2009 - 01/2007
3gefitinib (Iressa)FDA Link
09/2006 - 10/2005
2Somatostatin (Somatotropin Release-Inhibiting Factor)IBA
12/2015 - 01/2015
2ramucirumabIBA
05/2015 - 10/2014
2PlatinumIBA
10/2014 - 04/2012
2Epidermal Growth Factor (EGF)IBA
07/2014 - 04/2002
2Sirolimus (Rapamycin)FDA Link
11/2013 - 02/2011
2sorafenib (BAY 43-9006)FDA Link
05/2013 - 02/2013
2sunitinib (Sutent)FDA Link
04/2013 - 02/2011
2N-methylsuccinimideIBA
11/2012 - 01/2010
2HormonesIBA
03/2011 - 01/2005
2EmollientsIBA
10/2007 - 08/2005
1Dihydrouracil Dehydrogenase (NADP) (Dihydropyrimidine Dehydrogenase)IBA
11/2015
1Lipase (Acid Lipase)FDA Link
06/2015
1Trifluridine (Viroptic)FDA LinkGeneric
05/2015
1TAS 102IBA
05/2015
1Alanine Transaminase (SGPT)IBA
02/2015
1Creatine Kinase (Creatine Phosphokinase)IBA
02/2015
1Aspartate Aminotransferases (Aspartate Transaminase)IBA
02/2015
1Paclitaxel (Taxol)FDA LinkGeneric
10/2014
1Vascular Endothelial Growth Factor CIBA
10/2014
1Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA
10/2014

Therapy/Procedure

50Drug Therapy (Chemotherapy)
11/2015 - 01/2002
8Adjuvant Chemotherapy
07/2014 - 08/2004
4Radiotherapy
01/2014 - 12/2004
2Neoadjuvant Therapy
09/2008 - 03/2004
2Combination Drug Therapy (Combination Chemotherapy)
01/2008 - 08/2005
2Heterologous Transplantation (Xenotransplantation)
11/2007 - 06/2004