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Ben Tseng Selected Research

K 76 carboxylic acid

7/2009Discovery of 4-anilino-N-methylthieno[3,2-d]pyrimidines and 4-anilino-N-methylthieno[2,3-d]pyrimidines as potent apoptosis inducers.
4/2009Discovery of N-(4-methoxyphenyl)-N,2-dimethylquinazolin-4-amine, a potent apoptosis inducer and efficacious anticancer agent with high blood brain barrier penetration.
4/2009Discovery and structure-activity relationships of (2-(arylthio)benzylideneamino)guanidines as a novel series of potent apoptosis inducers.
8/2008Discovery of 2-chloro-N-(4-methoxyphenyl)-N-methylquinazolin-4-amine (EP128265, MPI-0441138) as a potent inducer of apoptosis with high in vivo activity.
6/2007MPC-6827: a small-molecule inhibitor of microtubule formation that is not a substrate for multidrug resistance pumps.
8/2005Discovery and structure-activity relationship of 3-aryl-5-aryl-1,2,4-oxadiazoles as a new series of apoptosis inducers and potential anticancer agents.

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Ben Tseng Research Topics

Disease

12Neoplasms (Cancer)
05/2009 - 11/2004
4Breast Neoplasms (Breast Cancer)
07/2009 - 01/2004
2Hepatocellular Carcinoma (Hepatoma)
05/2009 - 12/2008
2Colonic Neoplasms (Colon Cancer)
05/2009 - 12/2008
1Childhood Schizophrenia
12/2011
1Colorectal Neoplasms (Colorectal Cancer)
05/2009
1Prostatic Neoplasms (Prostate Cancer)
08/2008
1Leukemia
06/2007
1Carcinoma (Carcinomatosis)
06/2007
1Severe Acute Respiratory Syndrome
02/2006
1Myocardial Infarction
09/2003
1Liver Failure
09/2003
1Reperfusion Injury
09/2003
1Brain Ischemia (Cerebral Ischemia)
09/2003

Drug/Important Bio-Agent (IBA)

6K 76 carboxylic acidIBA
07/2009 - 08/2005
3Paclitaxel (Taxol)FDA LinkGeneric
05/2005 - 11/2004
2TubulinIBA
04/2009 - 08/2008
1Protons (Proton)IBA
12/2011
1piperazineIBA
05/2009
1N'- (4- bromo- 5- methyl- 2- oxoindolin- 3- ylidene)- 3,4,5- trimethoxybenzohydrazideIBA
05/2009
1quinolineIBA
12/2008
1AminesIBA
01/2008
1ATP-Binding Cassette Transporters (ABC Transporters)IBA
06/2007
1MPC-6827IBA
06/2007
1KetonesIBA
02/2006
1Transferrin Receptors (Transferrin Receptor)IBA
08/2005
15- (3- chlorothiophen- 2- yl)- 3- (5- chloropyridin- 2- yl)- 1,2,4- oxadiazoleIBA
08/2005
1Small Interfering RNA (siRNA)IBA
05/2005
1P-GlycoproteinIBA
12/2004
1Cisplatin (Platino)FDA LinkGeneric
11/2004
1gambogic acidIBA
01/2004
1benzyloxycarbonyl-valyl-aspartic acid fluoromethyl ketoneIBA
09/2003

Therapy/Procedure

4Heterologous Transplantation (Xenotransplantation)
04/2009 - 11/2004
1Homologous Transplantation (Allograft)
06/2007