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R M Tanguay Selected Research

B 581

8/2001Fumarylacetoacetate, the metabolite accumulating in hereditary tyrosinemia, activates the ERK pathway and induces mitotic abnormalities and genomic instability.

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R M Tanguay Research Topics

Disease

4Tyrosinemias (Tyrosinemia)
08/2001 - 01/2001
2Hepatocellular Carcinoma (Hepatoma)
05/2001 - 12/2000
2Fibrosis (Cirrhosis)
05/2001 - 12/2000
1Atherosclerosis
10/2006
1Hypertension (High Blood Pressure)
10/2001
1Chromosomal Instability (Chromosome Stability)
08/2001
1Liver Neoplasms (Liver Cancer)
08/2001
1Genomic Instability
08/2001
1Metabolic Diseases (Metabolic Disease)
08/2001
1Carcinoma (Carcinomatosis)
05/2001
1Shock
04/2001
1Liver Diseases (Liver Disease)
12/2000
1Liver Failure
12/2000
1Infection
04/2000

Drug/Important Bio-Agent (IBA)

4fumarylacetoacetase (fumarylacetoacetate hydrolase)IBA
08/2001 - 12/2000
3AntibodiesIBA
10/2001 - 04/2000
3Tyrosine (L-Tyrosine)FDA Link
05/2001 - 12/2000
2Heat-Shock Proteins (Heat-Shock Protein)IBA
10/2001 - 04/2001
1Benzo(a)pyreneIBA
10/2006
1PD 98059IBA
08/2001
1Glutathione (Reduced Glutathione)IBA
08/2001
1fumarylacetoacetateIBA
08/2001
1B 581IBA
08/2001
1Tyrosinemia type 1IBA
05/2001

Therapy/Procedure

1Liver Transplantation
05/2001