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Yoshiya Tanaka Selected Research

Rheumatoid Arthritis

1/2016	Efficacy and safety of olokizumab in Asian patients with moderate-to-severe rheumatoid arthritis, previously exposed to anti-TNF therapy: Results from a randomized phase II trial.
1/2016	The first double-blind, randomised, parallel-group certolizumab pegol study in methotrexate-naive early rheumatoid arthritis patients with poor prognostic factors, C-OPERA, shows inhibition of radiographic progression.
11/2015	Disease control by regulation of P-glycoprotein on lymphocytes in patients with rheumatoid arthritis.
11/2015	Evaluation of the pharmacokinetic equivalence and 54-week efficacy and safety of CT-P13 and innovator infliximab in Japanese patients with rheumatoid arthritis.
7/2015	Trend of patient characteristics and its impact on the response to adalimumab in patients with rheumatoid arthritis: post hoc time-course analysis of an all-case PMS in Japan.
7/2015	Efficacy and safety of tofacitinib as monotherapy in Japanese patients with active rheumatoid arthritis: a 12-week, randomized, phase 2 study.
5/2015	A multi-biomarker disease activity score tracks clinical response consistently in patients with rheumatoid arthritis treated with different anti-tumor necrosis factor therapies: A retrospective observational study.
5/2015	Longterm Safety and Efficacy of Subcutaneous Tocilizumab Monotherapy: Results from the 2-year Open-label Extension of the MUSASHI Study.
4/2015	Biologic-free remission of established rheumatoid arthritis after discontinuation of abatacept: a prospective, multicentre, observational study in Japan.
3/2015	Efficacy and safety of abatacept for patients with Sjögren's syndrome associated with rheumatoid arthritis: rheumatoid arthritis with orencia trial toward Sjögren's syndrome Endocrinopathy (ROSE) trial-an open-label, one-year, prospective study-Interim analysis of 32 patients for 24 weeks.

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Yoshiya Tanaka Research Topics

Disease

97	Rheumatoid Arthritis 01/2016 - 12/2002
18	Osteoporosis 05/2015 - 06/2005
16	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2016 - 10/2003
13	Inflammation 07/2015 - 03/2002
11	Infection 07/2015 - 02/2004
11	Autoimmune Diseases (Autoimmune Disease) 02/2015 - 02/2002
11	Neoplasms (Cancer) 12/2014 - 01/2002
10	Pathologic Processes 09/2015 - 03/2002
8	Bone Resorption 05/2015 - 08/2002
7	Hypercalcemia (Milk Alkali Syndrome) 03/2015 - 01/2004
7	Type 2 Diabetes Mellitus (MODY) 01/2015 - 01/2004
6	Arthritis (Polyarthritis) 07/2015 - 02/2004
6	Diabetes Mellitus 05/2014 - 06/2006
6	Atherosclerosis 01/2013 - 05/2003
5	Rheumatic Diseases (Rheumatism) 07/2013 - 01/2007
4	Drug Toxicity (Drug Safety) 01/2016 - 10/2011
4	Pneumonia (Pneumonitis) 11/2013 - 03/2009
4	Insulin Resistance 01/2013 - 01/2004
3	Graves Disease (Basedow Disease) 03/2015 - 01/2014
3	Hypophosphatemia 09/2014 - 01/2012
3	Lung Diseases (Lung Disease) 05/2014 - 11/2012
3	Hyperglycemia 01/2014 - 06/2005
3	Body Weight (Weight, Body) 01/2014 - 10/2008
3	Hypertension (High Blood Pressure) 01/2014 - 07/2012
3	Hypoglycemia (Reactive Hypoglycemia) 12/2012 - 02/2006
3	Dermatomyositis (Dermatopolymyositis) 06/2012 - 01/2008
3	Synovitis 06/2012 - 05/2003
3	Gastroesophageal Reflux (GERD) 02/2008 - 09/2005
2	Necrosis 09/2015 - 12/2014
2	Thyroiditis 06/2015 - 09/2003
2	Nausea 03/2015 - 01/2012
2	Vitamin D Deficiency 01/2015 - 12/2012
2	Primary Hyperparathyroidism 12/2014 - 01/2013
2	Neoplasm Metastasis (Metastasis) 09/2013 - 01/2012
2	Fibrosis (Cirrhosis) 07/2013 - 10/2009
2	Nasopharyngitis 05/2013 - 08/2011
2	Renal Tubular Acidosis (Distal Renal Tubular Acidosis) 03/2013 - 01/2012
2	Osteomalacia 03/2013 - 01/2012
2	Iron-Deficiency Anemia (Anemia, Iron Deficiency) 03/2013 - 01/2012
2	Hypocalcemia 03/2013 - 01/2013

Drug/Important Bio-Agent (IBA)

23	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 05/2015 - 06/2005
20	Methotrexate (Mexate)FDA LinkGeneric 01/2016 - 12/2002
14	Antirheumatic Agents (DMARD)IBA 11/2015 - 02/2004
14	TNFR-Fc fusion protein (etanercept)FDA Link 07/2014 - 01/2009
14	CytokinesIBA 07/2013 - 01/2002
12	tocilizumab FDA Link 05/2015 - 04/2011
11	Interleukin-6 (Interleukin 6)IBA 01/2016 - 11/2007
11	infliximab (Remicade)FDA Link 11/2015 - 01/2007
11	adalimumab (Humira)FDA Link 07/2015 - 06/2012
9	P-GlycoproteinIBA 11/2015 - 12/2004
9	Glucose (Dextrose)FDA LinkGeneric 05/2014 - 06/2005
9	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2014 - 01/2005
7	rituximab (Mabthera)FDA Link 01/2016 - 01/2007
7	Prednisolone (Predate)FDA LinkGeneric 06/2015 - 02/2004
6	CDP870 FDA Link 01/2016 - 07/2014
5	DiphosphonatesIBA 05/2015 - 03/2007
5	abatacept (BELATACEPT)FDA Link 04/2015 - 01/2014
5	AutoantibodiesIBA 02/2015 - 12/2002
5	Blood Glucose (Blood Sugar)IBA 01/2014 - 06/2006
5	Cyclophosphamide (Cytoxan)FDA LinkGeneric 09/2012 - 10/2003
4	Phosphotransferases (Kinase)IBA 09/2015 - 11/2012
4	CholesterolIBA 05/2015 - 12/2006
4	denosumab FDA Link 01/2015 - 05/2010
4	CalciumIBA 12/2014 - 07/2004
4	Insulin (Novolin)FDA Link 01/2014 - 01/2004
4	CreatinineIBA 01/2014 - 09/2002
4	Tacrolimus (Prograf)FDA LinkGeneric 11/2013 - 04/2007
4	AntigensIBA 06/2009 - 08/2002
4	Cyclosporine (Ciclosporin)FDA LinkGeneric 05/2005 - 02/2002
3	Collagen Type II (Type II Collagen)IBA 07/2015 - 01/2014
3	hydroxide ionIBA 01/2015 - 08/2002
3	Parathyroid Hormone (Parathormone)IBA 12/2014 - 04/2004
3	Carbon MonoxideIBA 07/2014 - 12/2010
3	GlucocorticoidsIBA 05/2014 - 03/2013
3	SCH 23390IBA 07/2013 - 08/2008
3	Biological Markers (Surrogate Marker)IBA 03/2013 - 03/2010
3	Interleukin-17 (Interleukin 27)IBA 01/2013 - 03/2011
3	Immunosuppressive Agents (Immunosuppressants)IBA 02/2012 - 10/2006
3	Etidronic Acid (HEDP)FDA LinkGeneric 01/2012 - 01/2004
3	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2012 - 03/2010
3	Dopamine (Intropin)FDA LinkGeneric 03/2011 - 08/2008
3	lansoprazole (Prevacid)FDA LinkGeneric 02/2008 - 09/2005
3	oxidized low density lipoproteinIBA 12/2007 - 02/2002
3	Hyaluronic Acid (Hyaluronan)IBA 12/2007 - 12/2006
2	Janus KinasesIBA 09/2015 - 01/2014
2	Thyroxine (Levothyroxine)FDA LinkGeneric 06/2015 - 03/2015
2	3-benzoyl dopamine (MBDA)IBA 05/2015 - 07/2013
2	Glucagon-Like Peptide 1 (GLP 1)IBA 01/2015 - 05/2014
2	Interleukin-10 (Interleukin 10)IBA 12/2014 - 01/2012
2	Teriparatide (Parathar)FDA Link 09/2014 - 02/2013
2	Hemoglobins (Hemoglobin)IBA 05/2014 - 03/2005
2	CalcineurinIBA 11/2013 - 03/2010
2	golimumab FDA Link 09/2013 - 06/2012
2	vogliboseIBA 07/2013 - 02/2006
2	saccharated ferric oxide FDA Link 03/2013 - 01/2012
2	Vitamin D FDA LinkGeneric 03/2013 - 12/2012

Therapy/Procedure

3	Biological Therapy 01/2014 - 11/2012
2	Parathyroidectomy 12/2014 - 01/2013
2	Aftercare (After-Treatment) 09/2014 - 01/2014
2	Remission Induction 07/2013 - 02/2004