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Cynthia Sung Selected Research

MDL 28574

8/2014Efficacy and safety of celgosivir in patients with dengue fever (CELADEN): a phase 1b, randomised, double-blind, placebo-controlled, proof-of-concept trial.
10/2012Dose- and schedule-dependent protective efficacy of celgosivir in a lethal mouse model for dengue virus infection informs dosing regimen for a proof of concept clinical trial.
12/2011Celgosivir treatment misfolds dengue virus NS1 protein, induces cellular pro-survival genes and protects against lethal challenge mouse model.

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Cynthia Sung Research Topics

Disease

4Infection
08/2014 - 11/2002
4Neoplasms (Cancer)
05/2004 - 06/2002
3Dengue (Dengue Fever)
08/2014 - 12/2011
2Stevens-Johnson Syndrome
11/2015 - 09/2012
2Toxic Epidermal Necrolysis (Lyell's Syndrome)
11/2015 - 09/2012
1Drug Toxicity (Drug Safety)
11/2015
1Gout
11/2015
1Hypersensitivity (Allergy)
02/2015
1Fever (Fevers)
08/2014
1Virus Diseases (Viral Diseases)
08/2014
1Epilepsy (Aura)
09/2012
1Neutropenia
12/2011
1Viremia
12/2011
1Asthma (Bronchial Asthma)
10/2011
1Multiple Myeloma
03/2003
1B-Cell Lymphoma (Lymphoma, B Cell)
03/2003
1Melanoma (Melanoma, Malignant)
11/2002
1Hepatitis B
11/2002

Drug/Important Bio-Agent (IBA)

3HLA-B Antigens (HLA-B)IBA
11/2015 - 09/2012
3MDL 28574IBA
08/2014 - 12/2011
1Biological Markers (Surrogate Marker)IBA
11/2015
1Probenecid (Benemid)FDA LinkGeneric
11/2015
1Uric Acid (Urate)IBA
11/2015
1Allopurinol (Remid)FDA LinkGeneric
11/2015
1abacavir (Ziagen)FDA Link
02/2015
1GlucosidasesIBA
08/2014
1Antiviral Agents (Antivirals)IBA
08/2014
1Phenytoin (Dilantin)FDA LinkGeneric
09/2012
1Carbamazepine (Tegretol)FDA LinkGeneric
09/2012
1Anticonvulsants (Antiepileptic Drugs)IBA
09/2012
1irinotecan (Camptosar)FDA LinkGeneric
12/2011
1AMG 317IBA
10/2011
1Interleukin-2 (IL2)IBA
05/2004
1B-Cell Activating FactorIBA
03/2003
1Interferon-alpha (Interferon Alfa)FDA Link
11/2002
1AntigensIBA
06/2002

Therapy/Procedure

1Aftercare (After-Treatment)
12/2011
1Intravenous Injections
03/2003