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Dennis J Stone Selected Research

9- (8- azabicyclo(3.2.1)oct- 3- ylidene)- 9H- xanthene- 3- carboxylic acid diethylamide

4/2009JNJ-20788560 [9-(8-azabicyclo[3.2.1]oct-3-ylidene)-9H-xanthene-3-carboxylic acid diethylamide], a selective delta opioid receptor agonist, is a potent and efficacious antihyperalgesic agent that does not produce respiratory depression, pharmacologic tolerance, or physical dependence.

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Dennis J Stone Research Topics

Disease

3Hyperalgesia
08/2010 - 02/2008
2Pain (Aches)
04/2009 - 02/2008
1Developmental Bone Diseases (Bone Dysplasia)
10/2010
1Hypertrophy
10/2010
1Respiratory Insufficiency (Respiratory Failure)
04/2009
1Constipation
04/2009
1Inflammation
04/2009
1Seizures (Seizure)
05/2008
1Neuralgia (Stump Neuralgia)
02/2008

Drug/Important Bio-Agent (IBA)

2Morphine (MS Contin)FDA LinkGeneric
04/2009 - 05/2008
2Analgesics (Analgesic Drugs)IBA
04/2009 - 02/2008
2TramadolFDA LinkGeneric
05/2008 - 02/2008
1Glucose (Dextrose)FDA LinkGeneric
10/2010
1Guanosine 5'-O-(3-Thiotriphosphate)IBA
08/2010
1Freund's AdjuvantIBA
08/2010
1Alfentanil (Alfenta)FDA LinkGeneric
04/2009
1delta Opioid Receptors (delta Opioid Receptor)IBA
04/2009
1Opioid Analgesics (Opioids)IBA
04/2009
19- (8- azabicyclo(3.2.1)oct- 3- ylidene)- 9H- xanthene- 3- carboxylic acid diethylamideIBA
04/2009
1Naloxone (Narcan)FDA LinkGeneric
05/2008
1Codeine (Codeine Phosphate)FDA LinkGeneric
05/2008
1Anticonvulsants (Antiepileptic Drugs)IBA
02/2008
1topiramate (Topamax)FDA LinkGeneric
02/2008

Therapy/Procedure

1Self Administration (Administration, Self)
04/2009
1Ligation
02/2008