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Paul M Stewart Selected Research

11-beta-Hydroxysteroid Dehydrogenase Type 2 (11 beta-Hydroxysteroid Dehydrogenase Type 2)

6/2009The hypertensiogenetic steroid 19-nor-progesterone does not influence cortisol inactivation by 11beta-hydroxysteroid dehydrogenase type 2.
9/2006Cortisol metabolism in hypertension.
8/2005Expression of renal 11beta-hydroxysteroid dehydrogenase type 2 is decreased in patients with impaired renal function.
8/2005Analysis of the 11beta-hydroxysteroid dehydrogenase type 2 gene (HSD11B2) in human essential hypertension.
10/2004Apparent mineralocorticoid excess syndrome: an overview.
9/2003Tissue-specific Cushing's syndrome, 11beta-hydroxysteroid dehydrogenases and the redefinition of corticosteroid hormone action.
8/2003Late-onset apparent mineralocorticoid excess caused by novel compound heterozygous mutations in the HSD11B2 gene.
6/2003Hypertension and the cortisol-cortisone shuttle.
4/2002Association studies between the HSD11B2 gene (encoding human 11beta-hydroxysteroid dehydrogenase type 2), type 1 diabetes mellitus and diabetic nephropathy.
1/2002Prereceptor regulation of glucocorticoid action by 11beta-hydroxysteroid dehydrogenase: a novel determinant of cell proliferation.

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Paul M Stewart Research Topics

Disease

21Obesity
10/2014 - 03/2002
17Hypertension (High Blood Pressure)
06/2014 - 04/2003
16Insulin Resistance
07/2015 - 09/2003
15Cushing Syndrome
06/2014 - 01/2002
8Kidney Diseases (Kidney Disease)
03/2012 - 11/2008
8Inflammation
01/2012 - 09/2005
7Neoplasms (Cancer)
01/2013 - 01/2003
7Abdominal Obesity
07/2012 - 04/2002
6Muscular Diseases (Myopathy)
06/2014 - 01/2002
6Acromegaly
02/2014 - 09/2002
6Osteoporosis
07/2012 - 06/2002
5Polycystic Ovary Syndrome (Syndrome, Stein-Leventhal)
03/2014 - 08/2003
4Arthritis (Polyarthritis)
02/2015 - 01/2012
4Adenoma (Adenomas)
09/2013 - 04/2005
4Hyperaldosteronism (Conn Syndrome)
09/2013 - 08/2010
4Proteinuria
10/2010 - 08/2005
3Hypopituitarism (Sheehan's Syndrome)
11/2015 - 03/2008
3Rheumatoid Arthritis
02/2015 - 01/2006
3Adrenal Insufficiency (Adrenal Gland Hypofunction)
09/2014 - 01/2006
3Glucose Intolerance
06/2014 - 10/2008
3Type 2 Diabetes Mellitus (MODY)
08/2012 - 02/2008
3Congenital Adrenal Hyperplasia (Hyperplasia, Congenital Adrenal)
06/2011 - 06/2004
3Cardiovascular Diseases (Cardiovascular Disease)
01/2011 - 01/2006
3Hypoglycemia (Reactive Hypoglycemia)
01/2011 - 12/2007
3Hyperplasia
12/2010 - 04/2005
3Weight Loss (Weight Reduction)
12/2010 - 06/2004
3Hypokalemia
09/2006 - 06/2003
3Breast Neoplasms (Breast Cancer)
04/2006 - 01/2003
2Hyperinsulinism (Hyperinsulinemia)
06/2014 - 06/2008
2Atrophy
06/2014 - 07/2013
2Weight Gain
05/2014 - 12/2007
2Liver Diseases (Liver Disease)
05/2014 - 01/2012
2Hypertrophy
09/2012 - 02/2007
2Osteosarcoma (Osteogenic Sarcoma)
08/2012 - 01/2002
2Fibrosis (Cirrhosis)
01/2012 - 09/2005
2Albuminuria
10/2010 - 08/2005
2Pituitary Diseases (Disease, Anterior Pituitary)
06/2010 - 01/2009
2Glaucoma
08/2005 - 10/2004
2Ectopic ACTH Syndrome
10/2004 - 06/2003
2Birth Weight (Birth Weights)
10/2004 - 06/2003
2Liver Cirrhosis (Hepatic Cirrhosis)
10/2004 - 06/2003
2Pre-Eclampsia (Preeclampsia)
10/2004 - 06/2003
2Prostatic Neoplasms (Prostate Cancer)
09/2004 - 01/2003
2Diabetes Mellitus
04/2003 - 09/2002
1Vitamin D Deficiency
07/2015
1Psoriatic Arthritis
02/2015
1Infection
01/2015

Drug/Important Bio-Agent (IBA)

34Hydrocortisone (Cortisol)FDA LinkGeneric
11/2015 - 01/2002
2511-beta-Hydroxysteroid Dehydrogenase Type 1IBA
12/2010 - 01/2002
17GlucocorticoidsIBA
04/2013 - 03/2002
11OxidoreductasesIBA
06/2014 - 09/2003
11Insulin (Novolin)FDA Link
03/2014 - 06/2004
1011-beta-Hydroxysteroid Dehydrogenase Type 2 (11 beta-Hydroxysteroid Dehydrogenase Type 2)IBA
06/2009 - 01/2002
8Glucose (Dextrose)FDA LinkGeneric
03/2014 - 09/2002
8Mineralocorticoid Receptors (Mineralocorticoid Receptor)IBA
03/2012 - 09/2003
8Messenger RNA (mRNA)IBA
01/2011 - 09/2004
7Adrenocorticotropic Hormone (ACTH)FDA Link
11/2015 - 08/2003
7hydroxide ionIBA
07/2015 - 01/2003
7CortisoneIBA
12/2010 - 01/2002
7HormonesIBA
11/2010 - 01/2003
6AldosteroneIBA
09/2013 - 04/2005
6Apparent mineralocorticoid excessIBA
06/2011 - 06/2003
5Insulin-Like Growth Factor I (IGF-1)IBA
07/2015 - 05/2003
5EnzymesIBA
10/2014 - 05/2005
5Growth Hormone (Somatotropin)IBA
02/2014 - 04/2003
5Spironolactone (Aldactone)FDA LinkGeneric
03/2012 - 08/2009
4methylamphotericin B (AME)IBA
08/2010 - 08/2003
411-beta-Hydroxysteroid Dehydrogenases (11beta Hydroxysteroid Dehydrogenase)IBA
01/2010 - 08/2005
3Vitamin DFDA LinkGeneric
07/2015 - 05/2005
3AndrogensIBA
03/2014 - 06/2004
3CorticosteroneIBA
09/2012 - 12/2007
3Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
03/2012 - 08/2009
3trichostatin A (A 300)IBA
04/2006 - 01/2003
3Calcitriol Receptors (Calcitriol Receptor)IBA
04/2006 - 09/2004
3SodiumIBA
08/2005 - 06/2003
2Non-alcoholic Fatty Liver DiseaseIBA
05/2014 - 01/2012
2Steroid 11-beta-Hydroxylase (11 beta-Hydroxylase)IBA
09/2013 - 01/2013
2Aldosterone Synthase (CYP11B2)IBA
09/2013 - 01/2013
2CollagenIBA
07/2013 - 11/2010
2CytokinesIBA
07/2012 - 01/2012
2Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA
03/2012 - 08/2009
2GlycogenIBA
01/2011 - 03/2008
2Dexamethasone (Maxidex)FDA LinkGeneric
01/2011 - 01/2002
2Angiotensin Receptor AntagonistsIBA
11/2010 - 08/2009
2Interleukin-6 (Interleukin 6)IBA
10/2010 - 09/2005
21,25-dihydroxyvitamin DIBA
11/2008 - 01/2006
2galactose-6-phosphate dehydrogenaseIBA
03/2008 - 12/2007
2Estrogen Receptor alphaIBA
12/2007 - 04/2006
2SteroidsIBA
12/2007 - 09/2006
2Cortisone reductase deficiencyIBA
07/2006 - 08/2003
2Histones (Histone)IBA
04/2006 - 01/2003
2Histone Deacetylase InhibitorsIBA
09/2004 - 01/2003
2Somatostatin (Somatotropin Release-Inhibiting Factor)IBA
03/2004 - 09/2002
1CholesterolIBA
07/2015
1TNFR-Fc fusion protein (etanercept)FDA Link
02/2015
1infliximab (Remicade)FDA Link
02/2015
1A-factor (Streptomyces)IBA
01/2015
1Biological Markers (Surrogate Marker)IBA
10/2014

Therapy/Procedure

4Radiotherapy
07/2014 - 03/2004
2Adrenalectomy
12/2010 - 04/2005