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Coen A Stegeman Selected Research

Myeloblastin (Proteinase 3)

12/2013Pathogenesis of ANCA-associated vasculitis: new possibilities for intervention.
10/2013Renal survival in proteinase 3 and myeloperoxidase ANCA-associated systemic vasculitis.
7/2012Genetically distinct subsets within ANCA-associated vasculitis.
7/2010IgG glycan hydrolysis attenuates ANCA-mediated glomerulonephritis.
9/2009Urinary CD4+ effector memory T cells reflect renal disease activity in antineutrophil cytoplasmic antibody-associated vasculitis.
10/2007Standardised assessment of membrane proteinase 3 expression. Analysis in ANCA-associated vasculitis and controls.
12/2006Mechanisms of Disease: pathogenesis and treatment of ANCA-associated vasculitides.
2/2005Occurrence of antineutrophil cytoplasmic antibodies and associated vasculitis in patients with hyperthyroidism treated with antithyroid drugs: A long-term followup study.
6/2004Renal expression of matrix metalloproteinases in human ANCA-associated glomerulonephritis.
4/2004Positive classic antineutrophil cytoplasmic antibody (C-ANCA) titer at switch to azathioprine therapy associated with relapse in proteinase 3-related vasculitis.
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Coen A Stegeman Research Topics

Disease

27Vasculitis (Vasculitides)
01/2016 - 01/2002
16Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
10/2014 - 05/2002
9Glomerulonephritis
12/2013 - 01/2002
8Inflammation
04/2013 - 01/2002
8Wegener Granulomatosis (Wegener's Granulomatosis)
07/2012 - 02/2002
6Microscopic Polyangiitis
12/2013 - 02/2002
6Systemic Vasculitis
10/2013 - 10/2003
5Proteinuria
01/2013 - 02/2003
3Infection
12/2013 - 02/2009
3Chronic Kidney Failure (Chronic Renal Failure)
10/2013 - 05/2004
2Granuloma
12/2013 - 02/2009
2Autoimmune Diseases (Autoimmune Disease)
04/2013 - 07/2008
2Nephritis
04/2013 - 07/2004
2Systemic Lupus Erythematosus (Libman-Sacks Disease)
01/2013 - 10/2007
2Churg-Strauss Syndrome (Allergic Angiitis)
01/2013 - 02/2002
2Renal Insufficiency (Renal Failure)
03/2012 - 07/2007
2Anti-Glomerular Basement Membrane Disease (Goodpasture's Syndrome)
06/2011 - 07/2004
2Necrosis
05/2010 - 06/2004
2Fibrosis (Cirrhosis)
12/2008 - 08/2006
1Lung Diseases (Lung Disease)
10/2014
1Atherosclerosis
01/2014
1Carotid Artery Diseases
01/2014
1Fatigue
01/2013
1Critical Illness (Critically Ill)
03/2012
1Acute Kidney Injury (Acute Renal Failure)
06/2011
1Hemorrhage
06/2011
1Bacterial Infections (Bacterial Infection)
01/2011
1Hematuria
07/2010
1Albuminuria
07/2010
1Cardiovascular Diseases (Cardiovascular Disease)
01/2010
1Rheumatoid Arthritis
10/2007
1Nephrosis
11/2005
1Hyperthyroidism
02/2005
1Secondary Hyperparathyroidism
05/2004
1Malnutrition
05/2004
1Kidney Diseases (Kidney Disease)
03/2003
1Hypertension (High Blood Pressure)
03/2003

Drug/Important Bio-Agent (IBA)

32Antineutrophil Cytoplasmic Antibodies (ANCA)IBA
01/2016 - 01/2002
17Myeloblastin (Proteinase 3)IBA
12/2013 - 01/2002
13Peroxidase (Myeloperoxidase)IBA
12/2013 - 02/2002
12AutoantibodiesIBA
12/2013 - 02/2002
11glucuronyl glucosamine glycan sulfate (Vessel)IBA
01/2016 - 05/2002
5AntibodiesIBA
02/2014 - 03/2002
4CreatinineIBA
10/2014 - 02/2003
3Cyclophosphamide (Cytoxan)FDA LinkGeneric
10/2014 - 04/2004
2antiglomerular basement membrane antibodyIBA
02/2014 - 07/2004
2HMGB1 Protein (HMG1)IBA
01/2014 - 01/2013
2C-Reactive ProteinIBA
01/2013 - 01/2010
2Immunoglobulin G (IgG)IBA
02/2011 - 07/2010
2Interleukin-17 (Interleukin 27)IBA
02/2009 - 07/2008
2Tissue Inhibitor of Metalloproteinase-1IBA
12/2007 - 06/2004
2Matrix MetalloproteinasesIBA
12/2007 - 06/2004
2AntigensIBA
07/2007 - 05/2002
2Adrenal Cortex Hormones (Corticosteroids)IBA
06/2007 - 01/2002
2Leukocyte Elastase (Neutrophil Elastase)IBA
02/2005 - 06/2004
1SteroidsIBA
10/2014
1rituximab (Mabthera)FDA Link
06/2014
1Advanced Glycosylation End ProductsIBA
01/2014
1Silicon Dioxide (Sand)FDA LinkGeneric
12/2013
1Immunodominant EpitopesIBA
04/2013
1Testosterone (Sustanon)FDA Link
01/2013
1PotassiumIBA
03/2012
1Glucose (Dextrose)FDA LinkGeneric
03/2012
1Insulin (Novolin)FDA Link
03/2012
1Rapidly progressive glomerulonephritis with pulmonary hemorrhageIBA
06/2011
1Bacterial DNAIBA
04/2011
1Toll-Like Receptors (Toll-Like Receptor)IBA
01/2011
1Chemokine ReceptorsIBA
01/2011
1Interleukin-2 (IL2)IBA
05/2010
1Interferon-gamma (Interferon, gamma)IBA
05/2010
1ThrombomodulinIBA
01/2010
1Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA
01/2010
1von Willebrand FactorIBA
01/2010
1HLA-DR4 Antigen (HLA DR4 Antigen)IBA
06/2009
1Immunoglobulins (Immunoglobulin)IBA
02/2009
1anti-endothelial cell antibodyIBA
02/2009
1CollagenIBA
12/2008
1Transforming Growth Factor beta (TGF-beta)IBA
12/2008
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
10/2007
1MethylprednisoloneFDA LinkGeneric
07/2007
1mycophenolate mofetil (Cellcept)FDA LinkGeneric
06/2007
1OsteopontinIBA
08/2006
1VimentinIBA
08/2006
1Fatty Acids (Saturated Fatty Acids)IBA
11/2005
1Oleic Acid (Oleate)IBA
11/2005
1Bovine Serum AlbuminIBA
11/2005
1Nonesterified Fatty Acids (NEFA)IBA
11/2005
1Antithyroid Agents (Antithyroid Drugs)IBA
02/2005
1Cathepsin GIBA
06/2004
1Dietary ProteinsIBA
05/2004
1Azathioprine (Imuran)FDA LinkGeneric
04/2004
1STF 62247IBA
03/2003

Therapy/Procedure

3Renal Replacement Therapy (Therapies, Renal Replacement)
10/2013 - 05/2004
3Transplants (Transplant)
12/2007 - 02/2003
2Remission Induction
06/2007 - 04/2004
1Plasmapheresis
10/2014
1Kidney Transplantation
10/2013
1Plasma Exchange
07/2007
1Parathyroidectomy
05/2004
1Transplantation (Transplant Recipients)
03/2003