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Paolo Simioni Selected Research

Factor V Deficiency

11/2013Antisense-based RNA therapy of factor V deficiency: in vitro and ex vivo rescue of a F5 deep-intronic splicing mutation.
1/2010Residual platelet factor V ensures thrombin generation in patients with severe congenital factor V deficiency and mild bleeding symptoms.
11/2008Low plasma levels of tissue factor pathway inhibitor in patients with congenital factor V deficiency.

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Paolo Simioni Research Topics

Disease

16Thrombosis (Thrombus)
12/2015 - 01/2003
14Thrombophilia
12/2015 - 10/2003
11Venous Thromboembolism
10/2013 - 03/2002
10Venous Thrombosis (Deep-Vein Thrombosis)
08/2014 - 10/2003
7Activated Protein C Resistance (APC Resistance)
08/2014 - 06/2002
6Neoplasms (Cancer)
01/2015 - 10/2009
5Fibrosis (Cirrhosis)
02/2015 - 07/2012
5Hemorrhage
03/2014 - 07/2008
5Stroke (Strokes)
10/2013 - 01/2007
4Protein S Deficiency (Deficiency, Protein S)
09/2010 - 01/2008
3Factor V Deficiency
11/2013 - 11/2008
2Necrosis
09/2015 - 01/2014
2Antiphospholipid Syndrome (Antiphospholipid Antibody Syndrome)
06/2015 - 06/2015
2Hepatitis B
02/2015 - 01/2015
2Liver Cirrhosis (Hepatic Cirrhosis)
01/2015 - 06/2014
1Thyroid Neoplasms (Thyroid Cancer)
09/2015
1Obesity
03/2015
1Sensorineural Hearing Loss
03/2015
1Overweight
01/2015
1Hepatocellular Carcinoma (Hepatoma)
01/2015
1Hepatitis
01/2015
1Pulmonary Embolism
08/2014
1Sepsis (Septicemia)
06/2014
1Infection
06/2014
1Shock
03/2014
1Ischemia
10/2013
1Edema
10/2013
1Glioma (Gliomas)
08/2013
1Asymptomatic Diseases
11/2012
1Spontaneous Abortion (Miscarriage)
03/2012
1Chickenpox
11/2011
1Thromboembolism
10/2011
1Lymphangioma (Cavernous Lymphangioma)
05/2010
1Protein C Deficiency
04/2010

Drug/Important Bio-Agent (IBA)

14factor V LeidenIBA
12/2015 - 03/2002
10Protein CIBA
12/2015 - 10/2002
10Prothrombin (Factor II)IBA
12/2015 - 10/2002
7Protein SIBA
12/2015 - 05/2006
7Factor V (Coagulation Factor V)IBA
08/2014 - 06/2002
5ThrombinFDA Link
01/2015 - 10/2005
5Fibrinogen (Factor I)FDA Link
08/2014 - 04/2005
5Factor VIIa (Activated Factor VII)IBA
08/2012 - 06/2010
4AntibodiesIBA
06/2015 - 07/2009
4Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA
11/2012 - 07/2008
3Thromboplastin (Tissue Factor)IBA
01/2015 - 05/2011
3AnticoagulantsIBA
04/2013 - 05/2006
3lipoprotein-associated coagulation inhibitor (TFPI)IBA
01/2012 - 11/2008
3Antiphospholipid AntibodiesIBA
10/2011 - 04/2010
2Glycoproteins (Glycoprotein)IBA
06/2015 - 06/2015
2Blood Coagulation Factors (Coagulation Factor)IBA
03/2015 - 01/2012
2Proteins (Proteins, Gene)IBA
02/2015 - 01/2015
2Annexin A5IBA
01/2015 - 01/2014
2Carbon MonoxideIBA
08/2014 - 03/2009
2glucuronyl glucosamine glycan sulfate (Vessel)IBA
10/2013 - 11/2012
2Factor IX (PTC)FDA LinkGeneric
04/2013 - 10/2009
2AntigensIBA
04/2013 - 04/2005
2ORALIT (ORS)IBA
10/2011 - 04/2010
2HomocysteineIBA
02/2011 - 01/2003
1medullary Thyroid cancerIBA
09/2015
1ZSTK474IBA
09/2015
1Immunoglobulin G (IgG)IBA
06/2015
1beta 2-Glycoprotein I (Apolipoprotein H)IBA
06/2015
1Cardiolipins (Cardiolipin)IBA
06/2015
1Dalteparin (Dalteparin Sodium)FDA Link
02/2015
1EndostatinsIBA
01/2015
1Platelet-Derived Growth FactorIBA
01/2015
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2015
1Angiogenic ProteinsIBA
01/2015
1Adenosine Monophosphate (AMP)IBA
01/2015
1Platelet Factor 4IBA
01/2015
1Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA
01/2015
1Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA
01/2015
1ThrombospondinsIBA
01/2015
1Benzene (Benzole)IBA
08/2014
1NickelIBA
08/2014
1ArsenicIBA
08/2014
1tigecycline (Tygacil)FDA Link
06/2014
1CaspasesIBA
01/2014
1ThymidineIBA
01/2014
1Fluorescein-5-isothiocyanate (FITC)IBA
01/2014
1everolimusFDA Link
01/2014
1Propidium (Propidium Iodide)IBA
01/2014
1Ouabain (G Strophanthin)IBA
01/2014
1RNA (Ribonucleic Acid)IBA
11/2013
1tebufenozide (Mimic)IBA
10/2013
1Blood Group Antigens (Blood Groups)IBA
04/2013
1Vitamin KFDA Link
11/2012
1Heparin (Liquaemin)FDA LinkGeneric
07/2012
1Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
03/2012
1SteroidsIBA
11/2011
1Antiviral Agents (Antivirals)IBA
11/2011
1AutoantibodiesIBA
11/2011
1plasma protein Z (protein Z)IBA
11/2011
1Factor VII (Proconvertin)IBA
02/2011
1fibrin fragment D (D-dimer)IBA
05/2010
1Lipoprotein(a)IBA
04/2010
1platelet factor VIBA
01/2010

Therapy/Procedure

2Transplants (Transplant)
11/2012 - 01/2012
1Surgical Portasystemic Shunt (Portosystemic Shunt)
07/2012
1Heterologous Transplantation (Xenotransplantation)
01/2012