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Norifumi Shioda Selected Research

spiro(imidazo- (1,2- a)pyridine- 3,2- indan)- 2(3H)- one

7/2008Spiro[imidazo[1,2-a]pyridine-3,2-indan]-2(3H)-one (ZSET1446/ST101) treatment rescues olfactory bulbectomy-induced memory impairment by activating Ca2+/calmodulin kinase II and protein kinase C in mouse hippocampus.

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Norifumi Shioda Research Topics

Disease

10Ischemia
10/2015 - 01/2006
10Brain Ischemia (Cerebral Ischemia)
10/2015 - 07/2006
9Hypertrophy
01/2014 - 12/2007
4Memory Disorders (Memory Loss)
10/2015 - 07/2008
4Cardiomegaly (Heart Hypertrophy)
01/2014 - 01/2009
3Alzheimer Disease (Alzheimer's Disease)
06/2011 - 02/2007
3Myocardial Infarction
11/2010 - 01/2008
3Myocardial Ischemia (Ischemic Heart Diseases)
10/2008 - 10/2007
2Body Weight (Weight, Body)
12/2011 - 12/2007
2Thalassemia
06/2011 - 01/2011
2X-Linked Mental Retardation (Mental Retardation, X Linked)
06/2011 - 01/2011
2Schizophrenia (Dementia Praecox)
04/2011 - 01/2009
2Catalepsy
04/2011 - 02/2010
2Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
01/2011 - 07/2006
2Aortic Valve Stenosis (Aortic Stenosis)
01/2009 - 12/2007
2Embolism (Embolus)
01/2008 - 09/2006
1Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
12/2014
1Cardiovascular Diseases (Cardiovascular Disease)
07/2013
1Neurodegenerative Diseases (Neurodegenerative Disease)
06/2011
1Mental Retardation (Idiocy)
01/2011
1T-Cell Lymphoma (Lymphoma, T Cell)
01/2011
1Neoplasm Metastasis (Metastasis)
01/2011
1Heart Failure
01/2011
1Neuroblastoma
02/2010
1Mental Disorders (Mental Disorder)
01/2010
1Bipolar Disorder (Mania)
01/2009
1Reperfusion Injury
10/2007
1Rhabdomyosarcoma
09/2007

Drug/Important Bio-Agent (IBA)

7Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA
10/2015 - 09/2006
6CalcineurinIBA
01/2011 - 07/2006
4Fas Ligand Protein (Fas Ligand)IBA
01/2011 - 09/2007
3Adenosine Triphosphate (ATP)IBA
10/2015 - 06/2011
3Fluvoxamine (Luvox)FDA LinkGeneric
01/2014 - 10/2010
3CalpainIBA
01/2011 - 07/2006
3Calcium-Calmodulin-Dependent Protein KinasesIBA
05/2010 - 09/2006
33- (2- (4- (3- chloro- 2- methylphenyl)1- piperazinyl)ethyl)5,6- dimethoxy- 1- (4- imidazolylmethyl)- 1H- indazol dihydrochloride 3.5 hydrateIBA
01/2009 - 01/2006
3Vanadium CompoundsIBA
01/2009 - 03/2008
3Phosphotransferases (Kinase)IBA
01/2009 - 03/2008
3Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA
01/2008 - 09/2006
2sigma-1 receptor (receptor 1, sigma)IBA
10/2015 - 10/2010
2Dehydroepiandrosterone (DHEA)IBA
10/2015 - 12/2011
2Angiotensin IIIBA
01/2014 - 12/2007
2Haloperidol (Haldol)FDA LinkGeneric
04/2011 - 02/2010
2N-Methylaspartate (NMDA)IBA
01/2011 - 02/2007
2Proteins (Proteins, Gene)IBA
01/2011 - 01/2010
23- (2- (4- (3- chloro- 2- methylphenyl)- 1- piperazinyl)ethyl)- 5,6- dimethoxyindazoleIBA
01/2009 - 12/2007
2Endothelin-1 (Endothelin 1)IBA
01/2009 - 12/2007
2Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
01/2009 - 03/2008
2oxovanadium IVIBA
01/2009 - 10/2008
2Tyrosine (L-Tyrosine)FDA Link
01/2008 - 01/2006
2DystrophinIBA
12/2007 - 12/2007
1AdenosineFDA LinkGeneric
10/2015
1methyl pyruvateIBA
12/2014
1Serotonin (5 Hydroxytryptamine)IBA
01/2014
1Nitric Oxide (Nitrogen Monoxide)FDA Link
07/2013
1Arginine (L-Arginine)FDA Link
07/2013
1serum P-component (CIt)IBA
07/2013
1CitrullineIBA
07/2013
1Arachidonic Acid (Vitamin F)IBA
06/2011
1ATR-X syndromeIBA
06/2011
1SCH 23390IBA
04/2011
1Dopamine D2 Receptors (Dopamine D2 Receptor)IBA
04/2011
1Carrier Proteins (Binding Protein)IBA
04/2011
1Sucrose (Saccharose)IBA
01/2011
1Calmodulin (Calcium-Dependent Activator Protein)IBA
01/2011
1Adenosine Triphosphatases (ATPase)IBA
01/2011
1Cysteine Proteases (Cysteine Protease)IBA
01/2011
1Serotonin Uptake Inhibitors (Serotonin Reuptake Inhibitors)IBA
11/2010
1Methamphetamine (Desoxyn)FDA LinkGeneric
02/2010
1QuinpiroleIBA
02/2010
1Dopamine (Intropin)FDA LinkGeneric
01/2010
1nobiletinIBA
10/2009
1Forkhead Transcription Factors (Forkhead Box Proteins)IBA
01/2009
1Nerve Growth Factors (Neurotrophins)IBA
01/2009
1U 0126 (UO 126)IBA
01/2009
1Bcl-2-like protein 11IBA
01/2009
1Atrial Natriuretic Factor (ANF)IBA
01/2009
1CytokinesIBA
01/2009
1Brain Natriuretic Peptide (Natrecor)FDA Link
01/2009
1Protein Tyrosine PhosphatasesIBA
10/2008
1pyridineIBA
07/2008
1spiro(imidazo- (1,2- a)pyridine- 3,2- indan)- 2(3H)- oneIBA
07/2008
1indanIBA
07/2008
1Glutamic Acid (Glutamate)FDA Link
01/2008
1vanadyl sulfateIBA
01/2008
1CASP8 and FADD-Like Apoptosis Regulating Protein (FLIP-S)IBA
01/2008
1phospholambanIBA
12/2007
1Phenylephrine (Neo-Synephrine)FDA LinkGeneric
12/2007
1Estrogens (Estrogen)FDA Link
12/2007
1salicylhydroxamic acid (SHAM)IBA
12/2007
1Nitric Oxide Synthase (NO Synthase)IBA
12/2007
1Transcription Factors (Transcription Factor)IBA
09/2007
1Tacrolimus (Prograf)FDA LinkGeneric
09/2007
1Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA
02/2007
1N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
02/2007
1LithiumIBA
09/2006

Therapy/Procedure

2Oral Administration
07/2013 - 07/2008
2Ovariectomy (Oophorectomy)
01/2009 - 12/2007
2Microspheres (Microsphere)
01/2008 - 09/2006
1Therapeutics
04/2011