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Charles N Serhan Selected Research

Autacoids

10/2014Aging delays resolution of acute inflammation in mice: reprogramming the host response with novel nano-proresolving medicines.
1/2014Resolvins, specialized proresolving lipid mediators, and their potential roles in metabolic diseases.
1/2013Novel n-3 immunoresolvents: structures and actions.
11/2011Regulation of inflammation in cancer by eicosanoids.
10/2011Antimicrobial aspects of inflammatory resolution in the mucosa: a role for proresolving mediators.
7/2011Specialized proresolving mediator targets for RvE1 and RvD1 in peripheral blood and mechanisms of resolution.
9/2005Anti-inflammatory circuitry: lipoxin, aspirin-triggered lipoxins and their receptor ALX.
2/2004Novel endogenous small molecules as the checkpoint controllers in inflammation and resolution: entrée for resoleomics.
4/2003Novel docosatrienes and 17S-resolvins generated from docosahexaenoic acid in murine brain, human blood, and glial cells. Autacoids in anti-inflammation.

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Charles N Serhan Research Topics

Disease

116Inflammation
12/2015 - 01/2002
21Peritonitis
06/2014 - 10/2002
12Infection
10/2015 - 06/2005
9Pain (Aches)
09/2013 - 11/2003
5Pneumonia (Pneumonitis)
09/2015 - 09/2002
4Atherosclerosis
03/2012 - 10/2008
4Neoplasms (Cancer)
11/2011 - 02/2002
3Obesity
07/2015 - 09/2012
3Wounds and Injuries (Trauma)
12/2014 - 06/2013
3Acute Lung Injury
11/2014 - 08/2009
3Lung Injury
11/2014 - 01/2013
3Colitis
01/2010 - 05/2005
3Asthma (Bronchial Asthma)
01/2007 - 09/2002
2Fibrosis (Cirrhosis)
12/2015 - 07/2015
2Emphysema
12/2015 - 01/2013
2Chronic Obstructive Pulmonary Disease (COPD)
10/2015 - 01/2013
2Reperfusion Injury
05/2015 - 01/2012
2Ischemia
11/2014 - 10/2003
2Tuberculosis (Tuberculoses)
01/2014 - 11/2008
2Neuralgia (Stump Neuralgia)
09/2013 - 04/2012
2Hyperalgesia
09/2013 - 03/2011
2Stroke (Strokes)
07/2012 - 10/2003
2Postoperative Pain
11/2011 - 03/2011
2Cardiovascular Diseases (Cardiovascular Disease)
03/2005 - 02/2004
2Osteoporosis
12/2004 - 04/2004
1Bacterial Infections (Bacterial Infection)
09/2015
1Kidney Diseases (Kidney Disease)
07/2015
1Fatty Liver
07/2015
1Myocardial Infarction
07/2015
1Animal Disease Models
08/2013
1Vascular System Injuries
06/2013

Drug/Important Bio-Agent (IBA)

35LipoxinsIBA
12/2015 - 01/2002
22Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
10/2014 - 01/2002
205S,12R,18R- trihydroxy- 6Z,8E,10E,14Z,16E- eicosapentaenoic acidIBA
01/2013 - 03/2005
15Eicosapentaenoic AcidIBA
09/2015 - 03/2005
14Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA
12/2015 - 01/2006
13resolvin D1IBA
12/2015 - 10/2008
11ZymosanIBA
06/2014 - 09/2004
10lipoxin A4IBA
07/2015 - 01/2002
10neuroprotectin D1IBA
09/2013 - 10/2005
9LeukotrienesIBA
02/2015 - 09/2002
9AutacoidsIBA
10/2014 - 04/2003
8ProstaglandinsIBA
09/2015 - 09/2002
8EicosanoidsIBA
09/2013 - 01/2006
6CytokinesIBA
10/2015 - 03/2006
5MicroRNAs (MicroRNA)IBA
11/2013 - 02/2011
5Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA
02/2013 - 07/2006
4Leukotriene B4IBA
09/2015 - 04/2003
4LipidsIBA
11/2012 - 01/2007
4Arachidonate 15-Lipoxygenase (Arachidonate 15 Lipoxygenase)IBA
01/2011 - 12/2003
4Prostaglandins E (PGE)IBA
11/2008 - 09/2004
4Arachidonic Acid (Vitamin F)IBA
10/2007 - 02/2004
3SmokeIBA
12/2015 - 01/2013
3Carbon MonoxideIBA
09/2015 - 06/2013
3resolvin D2IBA
07/2015 - 10/2009
3Interleukin-5 (Interleukin 5)IBA
02/2015 - 09/2002
37,14- dihydroxydocosa- 4,8,10,12,16,19- hexaenoic acidIBA
02/2015 - 04/2012
3Interleukin-13IBA
02/2015 - 09/2002
3Interleukin-10 (Interleukin 10)IBA
12/2014 - 05/2012
3EnzymesIBA
09/2013 - 12/2003
317- hydroxy- 4,7,10,13,15,19- docosahexaenoic acidIBA
06/2013 - 01/2009
3glucuronyl glucosamine glycan sulfate (Vessel)IBA
10/2010 - 02/2002
3Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
05/2010 - 05/2005
3Fatty Acids (Saturated Fatty Acids)IBA
03/2010 - 01/2007
3LipoxygenasesIBA
10/2008 - 02/2004
3Interleukin-12 (IL 12)IBA
06/2005 - 03/2005
2Immunoglobulin G (IgG)IBA
10/2014 - 05/2005
2CD59 AntigensIBA
06/2014 - 01/2009
2Biological Markers (Surrogate Marker)IBA
01/2014 - 01/2006
2Analgesics (Analgesic Drugs)IBA
09/2013 - 05/2010
2Capsaicin (Zostrix)FDA Link
04/2012 - 05/2010
2Proteins (Proteins, Gene)IBA
01/2012 - 01/2008
2Opioid Analgesics (Opioids)IBA
12/2011 - 05/2010
2Formaldehyde (Formol)FDA Link
12/2011 - 05/2010
2CarrageenanIBA
05/2010 - 08/2009
2Dinoprostone (PGE2)FDA Link
11/2008 - 04/2003
2C-Reactive ProteinIBA
11/2007 - 02/2004
2OxygenIBA
07/2007 - 06/2002
2Polyisoprenyl PhosphatesIBA
10/2005 - 09/2005
2Lipoxygenase (Lipoxygenase-1)IBA
12/2004 - 02/2004
2Anti-Inflammatory Agents (Anti-Inflammatories)IBA
08/2004 - 11/2002
1atorvastatin (Lipitor)FDA Link
09/2015
1Glucose (Dextrose)FDA LinkGeneric
07/2015
1S 6 (S-6)IBA
07/2015
1CollagenIBA
07/2015
1amphiregulin (schwannoma-derived growth factor)IBA
02/2015
1Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA
12/2014
1Antigen-Antibody Complex (Immune Complex)IBA
10/2014
1netrin-1IBA
06/2014
1Dihydrotachysterol (AT 10)IBA
01/2014
1Mixed Function Oxygenases (Monooxygenases)IBA
09/2013
1leukotriene A4 hydrolaseIBA
07/2013
1Heme Oxygenase-1IBA
06/2013
1Insulin (Novolin)FDA Link
06/2013

Therapy/Procedure

4Therapeutics
12/2014 - 04/2004
2Angioplasty (Angioplasty, Transluminal)
06/2013 - 10/2010
2Ligation
01/2013 - 10/2009
2Spinal Injections
10/2011 - 03/2011
1Critical Care
11/2014
1Vagotomy
06/2014