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Yutaka Seino Selected Research

gastric inhibitory polypeptide receptor

1/2021The Insulin Response to Oral Glucose in GIP and GLP-1 Receptor Knockout Mice: Review of the Literature and Stepwise Glucose Dose Response Studies in Female Mice.
1/2018Glucose-Dependent Insulinotropic Polypeptide Suppresses Peripheral Arterial Remodeling in Male Mice.
1/2018Inactivation of the Glucose-Dependent Insulinotropic Polypeptide Receptor Improves Outcomes following Experimental Myocardial Infarction.
1/2012Gipr is essential for adrenocortical steroidogenesis; however, corticosterone deficiency does not mediate the favorable metabolic phenotype of Gipr(-/-) mice.
12/2011Transgenic rescue of adipocyte glucose-dependent insulinotropic polypeptide receptor expression restores high fat diet-induced body weight gain.
12/2007Genetic inactivation of GIP signaling reverses aging-associated insulin resistance through body composition changes.
7/2006Gastric inhibitory polypeptide as an endogenous factor promoting new bone formation after food ingestion.
7/2002Inhibition of gastric inhibitory polypeptide signaling prevents obesity.

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Yutaka Seino Research Topics

Disease

110Type 2 Diabetes Mellitus (MODY)
08/2022 - 05/2002
28Insulin Resistance
02/2019 - 07/2002
26Body Weight (Weight, Body)
12/2021 - 04/2003
23Diabetes Mellitus
09/2020 - 01/2002
21Hypoglycemia (Reactive Hypoglycemia)
07/2018 - 09/2006
16Obesity
12/2022 - 07/2002
16Hyperglycemia
10/2017 - 01/2002
15Glucose Intolerance
01/2021 - 03/2003
8Type 1 Diabetes Mellitus (Autoimmune Diabetes)
09/2018 - 08/2002
6Weight Gain
09/2021 - 04/2014
4AIDS-Related Complex (ARC)
12/2022 - 06/2019
4Cardiovascular Diseases (Cardiovascular Disease)
05/2022 - 12/2013
4Myocardial Infarction
01/2021 - 05/2017
4Constipation
01/2021 - 10/2011
4Weight Loss (Weight Reduction)
08/2020 - 10/2010
4Diabetes Complications
12/2013 - 09/2008
3Anorexia
10/2021 - 06/2019
3Albuminuria
01/2020 - 03/2014
3Heart Failure
01/2020 - 05/2017
3Hypertension (High Blood Pressure)
10/2016 - 04/2008
3Ketosis
06/2015 - 08/2008
3Diabetic Nephropathies (Diabetic Nephropathy)
03/2014 - 08/2005
3Bone Fractures (Bone Fracture)
12/2013 - 07/2006
2Neoplasms (Cancer)
10/2021 - 06/2019
2Stroke (Strokes)
01/2021 - 01/2020
2Pain (Aches)
12/2020 - 12/2018
2Infections
12/2020 - 10/2010
2Sarcopenia
06/2019 - 06/2015
2Diabetic Ketoacidosis (Ketoacidosis, Diabetic)
03/2019 - 01/2017
2Nausea
01/2018 - 11/2015
2Non-alcoholic Fatty Liver Disease
01/2015 - 03/2013
2Bone Resorption
02/2014 - 02/2008

Drug/Important Bio-Agent (IBA)

59Glucose (Dextrose)FDA LinkGeneric
12/2022 - 11/2002
35Insulin (Novolin)FDA Link
12/2021 - 01/2002
20Glucagon-Like Peptide 1 (GLP 1)IBA
12/2022 - 02/2008
19Hypoglycemic Agents (Hypoglycemics)IBA
11/2020 - 12/2004
18LiraglutideFDA Link
08/2022 - 01/2011
17IncretinsIBA
05/2017 - 01/2007
161,5- anhydro- 1- (5- (4- ethoxybenzyl)- 2- methoxy- 4- methylphenyl)- 1- thioglucitolIBA
01/2020 - 07/2014
14Glucagon-Like Peptide-1 ReceptorIBA
01/2021 - 02/2008
13Pharmaceutical PreparationsIBA
10/2021 - 12/2006
12Blood Glucose (Blood Sugar)IBA
12/2021 - 07/2004
12Glycated Hemoglobin (Glycosylated Hemoglobin)IBA
09/2021 - 04/2003
10Glucagon (Glukagon)FDA Link
12/2021 - 11/2008
10Sitagliptin Phosphate (Januvia)FDA Link
01/2021 - 01/2011
9Triglycerides (Triacylglycerol)IBA
01/2018 - 10/2003
9alogliptinIBA
05/2017 - 09/2011
8Sodium-Glucose Transporter 2 InhibitorsIBA
05/2022 - 12/2014
8Dipeptidyl-Peptidase IV InhibitorsIBA
05/2022 - 06/2009
8gastric inhibitory polypeptide receptorIBA
01/2021 - 07/2002
7SodiumIBA
05/2022 - 04/2016
7lixisenatideIBA
12/2021 - 01/2015
7Glucagon-Like Peptide-1 Receptor AgonistsIBA
12/2021 - 05/2011
7AdiponectinIBA
02/2013 - 10/2005
6Peptides (Polypeptides)IBA
10/2021 - 05/2011
6LeptinIBA
02/2013 - 02/2004
5glimepiride (Amarel)FDA LinkGeneric
01/2021 - 10/2011
5Sodium-Glucose Transport ProteinsIBA
01/2020 - 07/2014
5Hormones (Hormone)IBA
01/2017 - 02/2004
5C-PeptideIBA
11/2015 - 08/2008
5LipidsIBA
01/2015 - 03/2005
4empagliflozinIBA
05/2022 - 03/2019
4semaglutideIBA
01/2022 - 01/2018
4AutoantibodiesIBA
10/2021 - 07/2003
4LinagliptinIBA
01/2021 - 10/2016
4rGLP-1 proteinIBA
09/2017 - 12/2009
4C-Reactive ProteinIBA
02/2013 - 12/2002
3GhrelinIBA
10/2021 - 06/2019
3ninjin'yoeitoIBA
10/2021 - 06/2019
3Cisplatin (Platino)FDA LinkGeneric
10/2021 - 06/2019
3Proteins (Proteins, Gene)FDA Link
08/2020 - 03/2008
3AlbuminsIBA
01/2020 - 02/2013
3Metformin (Glucophage)FDA LinkGeneric
07/2018 - 12/2012
3Japanese peopleIBA
01/2018 - 01/2003
3Glyburide (Glibenclamide)FDA LinkGeneric
04/2016 - 07/2014
3Carbon MonoxideIBA
01/2015 - 01/2002
3Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA
02/2013 - 10/2005
3Streptozocin (Streptozotocin)FDA Link
09/2011 - 02/2002
3Gastric Inhibitory Polypeptide (Glucose Dependent Insulinotropic Peptide)IBA
06/2009 - 07/2002
3corosolic acidIBA
04/2008 - 07/2004
3Adenosine Triphosphate (ATP)IBA
08/2006 - 12/2004
2Fura-2 (Fura 2)IBA
12/2022 - 06/2019
2ipragliflozinIBA
01/2021 - 01/2021
2omega-Chloroacetophenone (Mace)IBA
01/2021 - 01/2020
2Mason-Type DiabetesIBA
09/2020 - 05/2002
2Dietary FiberFDA Link
08/2020 - 06/2013
2CarbohydratesIBA
08/2020 - 01/2017
2Fatty Acids (Saturated Fatty Acids)IBA
08/2020 - 08/2014
2Appetite Depressants (Anorectics)IBA
01/2020 - 06/2019
22,4-thiazolidinedione (thiazolidinedione)IBA
07/2018 - 01/2018
2saxagliptinFDA Link
12/2017 - 05/2017
2EnzymesIBA
01/2015 - 09/2014
2Insulin Glargine (Lantus)FDA Link
12/2014 - 12/2013
2Hemoglobins (Hemoglobin)IBA
07/2014 - 05/2007
2Biological ProductsIBA
12/2013 - 03/2013

Therapy/Procedure

29Glycemic Control
09/2021 - 10/2005
27Therapeutics
01/2021 - 03/2003
3Kampo Medicine (Kampo)
10/2021 - 06/2019
3Transplantation
10/2011 - 02/2002
3Islets of Langerhans Transplantation
03/2008 - 09/2006