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Jay S Schneider Selected Research

G(M1) Ganglioside

1/2022GM1 ganglioside modifies microglial and neuroinflammatory responses to α-synuclein in the rat AAV-A53T α-synuclein model of Parkinson's disease.
10/2019GM1 Ganglioside Modifies α-Synuclein Toxicity and is Neuroprotective in a Rat α-Synuclein Model of Parkinson's Disease.
1/2019Gangliosides: Treatment Avenues in Neurodegenerative Disease.
9/2015GM1 ganglioside in Parkinson's disease: Pilot study of effects on dopamine transporter binding.
1/2015Intraventricular Sialidase Administration Enhances GM1 Ganglioside Expression and Is Partially Neuroprotective in a Mouse Model of Parkinson's Disease.
1/2013A randomized, controlled, delayed start trial of GM1 ganglioside in treated Parkinson's disease patients.
5/2010GM1 ganglioside in Parkinson's disease: Results of a five year open study.

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Jay S Schneider Research Topics

Disease

23Parkinson Disease (Parkinson's Disease)
01/2022 - 12/2006
9Parkinsonian Disorders (Parkinsonism)
05/2013 - 08/2002
7Cognitive Dysfunction
01/2021 - 03/2004
3Alzheimer Disease (Alzheimer's Disease)
01/2019 - 04/2013
3Neurodegenerative Diseases (Neurodegenerative Disease)
01/2019 - 08/2011
3Disease Progression
04/2017 - 02/2015
2Inflammation (Inflammations)
01/2022 - 06/2008
1Neuroinflammatory Diseases
01/2022
1Dyskinesias (Dyskinesia)
01/2021
1Stroke (Strokes)
01/2019
1Dementia (Dementias)
04/2014
1Body Weight (Weight, Body)
01/2014
1Neurobehavioral Manifestations
03/2013
1Synucleinopathies
03/2013
1Schizophrenia (Dementia Praecox)
09/2011
1Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder)
09/2011
1Nerve Degeneration
10/2010
1Pathologic Processes
12/2006
1Hypokinesia (Bradykinesia)
01/2003
1MPTP Poisoning
08/2002

Drug/Important Bio-Agent (IBA)

7G(M1) GangliosideIBA
01/2022 - 05/2010
71- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA
05/2013 - 01/2003
5Dopamine (Intropin)FDA LinkGeneric
01/2021 - 12/2006
4CreatineIBA
04/2017 - 01/2014
4ManganeseIBA
03/2013 - 12/2006
3SynucleinsIBA
01/2022 - 03/2013
3Messenger RNA (mRNA)IBA
01/2022 - 01/2003
3Levodopa (L Dopa)FDA LinkGeneric
01/2021 - 05/2013
3GangliosidesIBA
01/2019 - 01/2018
2Neuroprotective AgentsIBA
01/2022 - 12/2006
2EnzymesIBA
01/2019 - 01/2003
2Caffeine (No Doz)FDA LinkGeneric
04/2017 - 09/2015
2gamma-Aminobutyric Acid (GABA)IBA
01/2003 - 08/2002
1Norepinephrine Plasma Membrane Transport Proteins (Norepinephrine Transporter)IBA
01/2021
1Amyloid (Amyloid Fibrils)IBA
01/2019
1Phosphoric Monoester Hydrolases (Phosphatases)IBA
01/2018
1Dopamine Plasma Membrane Transport Proteins (Dopamine Transporter)IBA
09/2015
1Neuraminidase (Sialidase)IBA
01/2015
1Retinaldehyde (Retinal)IBA
10/2014
1alpha-SynucleinIBA
04/2014
1Biological ProductsIBA
04/2014
1Galantamine (Galanthamine)FDA LinkGeneric
04/2013
1Memantine (Namenda)FDA Link
04/2013
1Therapeutic UsesIBA
03/2012
1alpha-2 Adrenergic ReceptorsIBA
09/2011
1Proteins (Proteins, Gene)FDA Link
08/2011
11-Methyl-4-phenylpyridinium (1 Methyl 4 phenylpyridinium)IBA
10/2010
1Dopamine D3 ReceptorsIBA
09/2010
1N- (4- (2- (8- cyano- 1,3a,4,9b- tetrahydro(1)benzopyrano(3,4- c)pyrrol- 2(3H)- yl)ethyl)phenyl)acetamideIBA
09/2010
1UbiquitinIBA
06/2008
1CholesterolIBA
06/2008
1Proteasome Endopeptidase Complex (Proteasome)IBA
06/2008
1Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA
09/2007
1preprotachykininIBA
11/2004
1OligodeoxyribonucleotidesIBA
01/2003
1Glutamate Decarboxylase (Decarboxylase, Glutamate)IBA
01/2003
1Protein Isoforms (Isoforms)IBA
01/2003
1mu Opioid Receptors (mu Opioid Receptor)IBA
08/2002
1EnkephalinsIBA
08/2002
1GABA-A Receptors (GABA(A) Receptor)IBA
08/2002

Therapy/Procedure

6Therapeutics
01/2021 - 07/2010
1Activities of Daily Living (ADL)
01/2014
1Drug Therapy (Chemotherapy)
04/2013