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Hironobu Sasano Selected Research

Estrogens (Estrogen)

11/2015Intracrine steroid production and mammalian target of rapamycin pathways in pulmonary lymphangioleiomyomatosis.
10/2015Immunolocalization of thymidylate synthase as a favorable prognostic marker in estrogen receptor-positive breast carcinoma.
4/2015Androgen receptor and enzymes in lymph node metastasis and cancer reoccurrence in triple-negative breast cancer.
4/2015Clinical significance of subtype classification in metastatic lymph nodes of breast cancer patients undergoing neoadjuvant chemotherapy.
2/2015Prostaglandin E2 inhibits p53 in human breast adipose stromal cells: a novel mechanism for the regulation of aromatase in obesity and breast cancer.
1/2015The intracrinology of breast cancer.
1/2015Prognostic significance of proline, glutamic acid, leucine rich protein 1 (PELP1) in triple-negative breast cancer: a retrospective study on 129 cases.
10/2014Increased androgen receptor activity and cell proliferation in aromatase inhibitor-resistant breast carcinoma.
8/2014Evaluating the 21-gene assay Recurrence Score® as a predictor of clinical response to 24 weeks of neoadjuvant exemestane in estrogen receptor-positive breast cancer.
7/2014Tissue concentrations of estrogens and aromatase immunolocalization in interstitial pneumonia of human lung.
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Hironobu Sasano Research Topics

Disease

135Neoplasms (Cancer)
11/2015 - 06/2002
105Carcinoma (Carcinomatosis)
10/2015 - 01/2002
92Breast Neoplasms (Breast Cancer)
11/2015 - 01/2002
49Adenoma (Adenomas)
10/2015 - 03/2002
31Hyperaldosteronism (Conn Syndrome)
10/2015 - 03/2002
22Hyperplasia
10/2015 - 03/2002
21Cushing Syndrome
10/2015 - 07/2002
21Neoplasm Metastasis (Metastasis)
04/2015 - 02/2004
14Noninfiltrating Intraductal Carcinoma (DCIS)
10/2015 - 03/2006
14Adrenocortical Carcinoma
06/2015 - 04/2006
14Ductal Carcinoma
11/2014 - 02/2004
12Endometrial Neoplasms (Endometrial Cancer)
11/2014 - 06/2002
11Hypertension (High Blood Pressure)
09/2015 - 07/2002
11Adenocarcinoma
03/2015 - 06/2002
11Adrenocortical Adenoma (Disease, Conn's)
01/2015 - 08/2003
10Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2014 - 07/2005
9Hypokalemia
01/2014 - 03/2002
8Prostatic Neoplasms (Prostate Cancer)
05/2013 - 07/2004
7Ovarian Neoplasms (Ovarian Cancer)
07/2011 - 07/2002
6Neuroendocrine Tumors (Neuroendocrine Tumor)
01/2015 - 07/2007
6Pheochromocytoma
01/2009 - 05/2002
5Squamous Cell Carcinoma (Epidermoid Carcinoma)
01/2015 - 03/2004
4Hepatocellular Carcinoma (Hepatoma)
03/2014 - 08/2002
4Lung Neoplasms (Lung Cancer)
10/2012 - 07/2011
4Fibrosis (Cirrhosis)
07/2010 - 01/2003
4Atherosclerosis
07/2006 - 10/2003
3Inflammation
09/2015 - 02/2002
3Obesity
02/2015 - 01/2013
3Residual Neoplasm
01/2015 - 03/2007
3Anoxia (Hypoxia)
01/2015 - 01/2013
3Endometrioid Carcinoma
08/2012 - 06/2003
3Insulin Resistance
07/2011 - 12/2007
3Diabetes Mellitus
07/2011 - 12/2007
3Chronic Kidney Failure (Chronic Renal Failure)
07/2010 - 08/2003

Drug/Important Bio-Agent (IBA)

113Estrogens (Estrogen)FDA Link
11/2015 - 01/2002
65Aromatase (CYP19)IBA
11/2015 - 01/2002
57Messenger RNA (mRNA)IBA
05/2015 - 03/2002
53EnzymesIBA
11/2015 - 01/2002
53AldosteroneIBA
10/2015 - 03/2002
39HormonesIBA
11/2015 - 01/2003
37Hydrocortisone (Cortisol)FDA LinkGeneric
10/2015 - 07/2002
27Aromatase InhibitorsIBA
10/2014 - 09/2003
26SteroidsIBA
06/2015 - 01/2002
24Progesterone Receptors (Progesterone Receptor)IBA
10/2015 - 07/2002
22Adrenocorticotropic Hormone (ACTH)FDA Link
10/2015 - 03/2002
22AndrogensIBA
02/2015 - 03/2005
21OxidoreductasesIBA
11/2015 - 04/2005
19Androgen Receptors (Androgen Receptor)IBA
11/2015 - 06/2002
18Estradiol (Estrace)FDA LinkGeneric
05/2013 - 05/2003
15Steryl-Sulfatase (Steroid Sulfatase)IBA
07/2011 - 01/2002
153 (or 17)-beta-hydroxysteroid dehydrogenaseIBA
06/2010 - 01/2002
13Biological Markers (Surrogate Marker)IBA
04/2015 - 10/2007
12Estrogen Receptor alphaIBA
04/2009 - 05/2003
11Estrogen Receptor betaIBA
05/2013 - 03/2004
10ProgesteroneFDA LinkGeneric
01/2015 - 07/2002
10estrone sulfotransferaseIBA
07/2011 - 01/2002
9ReninIBA
01/2014 - 03/2002
9TamoxifenFDA LinkGeneric
09/2010 - 07/2004
8Protein Isoforms (Isoforms)IBA
06/2015 - 05/2002
8Epidermal Growth Factor Receptor (EGF Receptor)IBA
04/2015 - 12/2008
8Dehydroepiandrosterone (DHEA)IBA
01/2015 - 09/2003
8Testosterone (Sustanon)FDA Link
09/2014 - 06/2002
8Steroid Receptors (Steroid Receptor)IBA
11/2011 - 05/2003
7MicroRNAs (MicroRNA)IBA
04/2015 - 01/2010
7Phenobarbital (Luminal)FDA Link
04/2015 - 03/2006
7ParaffinIBA
11/2014 - 01/2004
7Formaldehyde (Formol)FDA Link
11/2014 - 09/2005
7Proteins (Proteins, Gene)IBA
11/2014 - 01/2006
7Aldosterone Synthase (CYP11B2)IBA
08/2014 - 08/2004
7Estrone (Folliculin)FDA Link
05/2011 - 05/2003
711-beta-Hydroxysteroid Dehydrogenase Type 2 (11 beta-Hydroxysteroid Dehydrogenase Type 2)IBA
01/2008 - 11/2002
6Transcription Factors (Transcription Factor)IBA
11/2015 - 09/2003
6Carbon MonoxideIBA
01/2015 - 01/2004
6exemestane (Aromasin)FDA Link
08/2014 - 06/2010
6Estrogen ReceptorsIBA
10/2012 - 03/2008
6RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
09/2012 - 06/2002
5LigandsIBA
09/2015 - 07/2006
5dehydroepiandrosterone sulfotransferaseIBA
01/2015 - 08/2003
5PotassiumIBA
01/2011 - 07/2002
4Sirolimus (Rapamycin)FDA Link
11/2015 - 03/2012
4Somatostatin (Somatotropin Release-Inhibiting Factor)IBA
05/2015 - 07/2007
4Adenocarcinoma of lungIBA
04/2015 - 08/2010
4Keratins (Keratin)IBA
03/2015 - 05/2006
4Steroid 21-Hydroxylase (21 Hydroxylase)IBA
01/2015 - 01/2010
4GlucocorticoidsIBA
01/2013 - 01/2003
4PPAR gammaIBA
07/2011 - 07/2006
4Glucose (Dextrose)FDA LinkGeneric
01/2011 - 07/2006
3Vasopressins (Vasopressin)IBA
10/2015 - 02/2004
3MineralocorticoidsIBA
10/2015 - 01/2003
3Small Interfering RNA (siRNA)IBA
04/2014 - 02/2009
3anastrozole (Arimidex)FDA LinkGeneric
06/2013 - 03/2008
3Steroid 17-alpha-Hydroxylase (17 alpha Hydroxylase)IBA
01/2013 - 06/2007
3Epidermal Growth Factor (EGF)IBA
12/2012 - 03/2008
3letrozole (Femara)FDA LinkGeneric
07/2012 - 01/2009
3CytokinesIBA
08/2010 - 01/2008

Therapy/Procedure

19Adrenalectomy
01/2015 - 03/2002
12Lasers (Laser)
11/2013 - 06/2003
11Drug Therapy (Chemotherapy)
04/2015 - 10/2005
4Aftercare (After-Treatment)
05/2014 - 08/2007
3Neoadjuvant Therapy
03/2012 - 04/2010