HOMEPRODUCTSSERVICESCOMPANYCONTACTFAQResearchDictionaryPharmaMobileSign Up FREE or Login

Ashok K Saluja Selected Research

triptolide

10/2015Targeting HSF1 disrupts HSP90 chaperone function in chronic lymphocytic leukemia.
6/2015Triptolide abrogates growth of colon cancer and induces cell cycle arrest by inhibiting transcriptional activation of E2F.
5/2015Primary and liver metastasis-derived cell lines from KrasG12D; Trp53R172H; Pdx-1 Cre animals undergo apoptosis in response to triptolide.
3/2015Triptolide and its prodrug minnelide suppress Hsp70 and inhibit in vivo growth in a xenograft model of mesothelioma.
1/2015Minnelide effectively eliminates CD133(+) side population in pancreatic cancer.
6/2014Triptolide sensitizes pancreatic cancer cells to TRAIL-induced activation of the death receptor pathway.
6/2014Triptolide activates unfolded protein response leading to chronic ER stress in pancreatic cancer cells.
11/2013Triptolide-induced cell death in pancreatic cancer is mediated by O-GlcNAc modification of transcription factor Sp1.
7/2013Minnelide reduces tumor burden in preclinical models of osteosarcoma.
7/2013Triptolide induces the expression of miR-142-3p: a negative regulator of heat shock protein 70 and pancreatic cancer cell proliferation.
For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research network!


Choose Username:
Email:
Password:
Verify Password:
Type Validation Code Shown:


Ashok K Saluja Research Topics

Disease

18Neoplasms (Cancer)
10/2015 - 10/2007
17Pancreatitis
10/2014 - 01/2002
15Pancreatic Neoplasms (Pancreatic Cancer)
06/2015 - 10/2007
5Inflammation
09/2012 - 11/2002
4Necrosis
12/2011 - 11/2002
3Shock
10/2015 - 04/2013
3Neoplasm Metastasis (Metastasis)
06/2015 - 10/2007
3Chronic Pancreatitis
09/2013 - 10/2011
3Lung Injury
09/2013 - 09/2002
3Neuroblastoma
04/2013 - 08/2009
2Adenocarcinoma
07/2013 - 08/2010
2Cholangiocarcinoma
06/2011 - 10/2010
2Hyperamylasemia
04/2008 - 01/2007
2Edema
04/2008 - 01/2007
1Leukemia
10/2015
1Aneuploidy (Aneuploid)
10/2015
1Colonic Neoplasms (Colon Cancer)
06/2015
1Colorectal Neoplasms (Colorectal Cancer)
06/2015
1Mesothelioma
03/2015
1Osteosarcoma (Osteogenic Sarcoma)
07/2013
1Residual Neoplasm
09/2010
1Pneumonia (Pneumonitis)
05/2009

Drug/Important Bio-Agent (IBA)

21triptolideIBA
10/2015 - 10/2007
11Caerulein (Ceruletide)IBA
10/2014 - 01/2002
8TrypsinogenIBA
10/2014 - 01/2002
4TrypsinIBA
09/2013 - 11/2002
4HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA
07/2013 - 01/2002
3Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
06/2014 - 02/2010
3NF-kappa B (NF-kB)IBA
09/2013 - 09/2012
3Small Interfering RNA (siRNA)IBA
01/2012 - 09/2010
3Cholecystokinin (Pancreozymin)IBA
04/2007 - 09/2002
2Heat-Shock Proteins (Heat-Shock Protein)IBA
10/2015 - 08/2009
2L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
06/2015 - 11/2002
2Transcription Factors (Transcription Factor)IBA
05/2015 - 12/2011
2Caspase 3 (Caspase-3)IBA
05/2015 - 02/2010
2DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA
05/2015 - 09/2010
2Messenger RNA (mRNA)IBA
04/2013 - 07/2007
2Cathepsin BIBA
01/2012 - 09/2002
2ChemokinesIBA
10/2010 - 01/2007
2Peroxidase (Myeloperoxidase)IBA
07/2008 - 09/2002
2Arginine (L-Arginine)FDA Link
04/2008 - 04/2007
1Proteins (Proteins, Gene)IBA
05/2015
1Annexin A5IBA
05/2015
1Sodium Chloride (Saline Solution)FDA LinkGeneric
03/2015
1Staphylococcal Protein A (A, Protein)IBA
03/2015
1Peptide Initiation Factors (Initiation Factor)IBA
06/2014
1Inositol (Myoinositol)IBA
06/2014
1Phosphotransferases (Kinase)IBA
06/2014
1Sp1 Transcription FactorIBA
11/2013
1Interleukin-6 (Interleukin 6)IBA
09/2013
1MicroRNAs (MicroRNA)IBA
07/2013
1Molecular Chaperones (Chaperone, Molecular)IBA
07/2013
1Apoptosis Regulatory ProteinsIBA
01/2013
1Glycoproteins (Glycoprotein)IBA
01/2012
1RNA (Ribonucleic Acid)IBA
01/2012
1GO 201IBA
01/2012
1Transcription Factor AP-1 (Transcription Factor AP 1)IBA
10/2010
1Death Domain ReceptorsIBA
10/2010
1Chemotactic FactorsIBA
10/2010
1Interleukin-13IBA
08/2010
1Interleukin-13 Receptors (Interleukin 13 Receptor)IBA
08/2010
1Epidermal Growth Factor (EGF)IBA
08/2010
1Caspase 9IBA
02/2010
1Ritonavir (Norvir)FDA Link
05/2009
1Cytochromes c (Cytochrome c)IBA
05/2009
1CalciumIBA
05/2009
1QuercetinIBA
05/2009
1HIV Protease InhibitorsIBA
05/2009
1Nelfinavir (Viracept)FDA Link
05/2009
11- palmitoyl- 2- (10- (4- ((trifluoromethyl)diazirinyl)phenyl)- 8- oxadecanoyl)- sn- glycero- 3- phosphocholineIBA
05/2009
1sodium arseniteIBA
04/2008
1HydrolasesIBA
01/2007
1tebufenozide (Mimic)IBA
01/2007
1Enzyme Precursors (Zymogens)IBA
01/2007
1CytokinesIBA
01/2007
1Ethanol (Ethyl Alcohol)IBA
11/2003
1AmylasesFDA Link
11/2002
1Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA
11/2002
1Cyclooxygenase 2 (Cyclooxygenase-2)IBA
11/2002
1Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
09/2002
1CA 074 methyl esterIBA
09/2002
1AntibodiesIBA
09/2002

Therapy/Procedure

4Heterologous Transplantation (Xenotransplantation)
06/2015 - 10/2012
4Injections
03/2015 - 11/2002
4Drug Therapy (Chemotherapy)
07/2013 - 10/2007
2Intraperitoneal Injections
05/2013 - 09/2002
1Therapeutics
06/2015
1Aftercare (After-Treatment)
03/2015
1Induced Hyperthermia (Thermotherapy)
01/2002